DCR:急性重症溃疡性结肠炎早期行手术治疗效果好

2020-01-29 不详 MedSci原创

与正在进行的药物治疗相比,越来越多的证据支持在急性暴发性溃疡性结肠炎中立即进行结肠切除术可以取得理想的疗效,因此,本项研究的目的是比较早期与延迟结肠切除术的溃结患者预后的差异。

背景:
与正在进行的药物治疗相比,越来越多的证据支持在急性暴发性溃疡性结肠炎中立即进行结肠切除术可以取得理想的疗效,因此,本项研究的目的是比较早期与延迟结肠切除术的溃结患者预后的差异。

方法:
这是一项针对队列性溃疡溃疡性结肠炎患者对照研究,研究人员在美国国家外科手术质量改善计划数据库中确定了2005年至2015年因溃疡性结肠炎而接受急诊全腹腔结肠切除术的成年患者的临床数据。主要观察指标:术后30天内国家外科手术质量改善计划报告的死亡率和术后并发症,以及入院后2天内的早期手术。

结果:
倾向得分匹配后,研究人员确定了573个手术病例。早期组中位手术时间为1个住院日,而延迟组为6个院日(p <0.001)。早期手术与较低的死亡率(4.9% VS 20.3%,p <0.001)和较低的并发症发生率(64.5% VS 72.0%,p = 0.052)相关。对术前危险因素进行死亡率加权加权的多变量logistic回归表明,与延迟手术相比,早期手术可使死亡几率降低82%(p<0.001)。术前危险因素的发病率回归表明,早期手术与延迟手术的并发症几率降低35%(p = 0.034)。

结论:
立即接受手术治疗的急性溃疡性结肠炎患者的术后并发症和死亡率降低。

原始出处:

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    2020-03-31 nymo
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    2020-01-30 1478fa69m73暂无昵称

    手术毕竟患者接受程度不太满意

    0

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    2020-01-30 thm112988

    0

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    2020-01-29 内科新手

    谢谢梅斯提供这么好的信息,学到很多

    0

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    2020-01-29 CHANGE

    疗效只是效果的众多方面之一,还要看对患者的获益,包括生活质量等因素共同决定效果的

    0

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