Diabetic Med：巨细胞病毒血清阳性与2型糖尿病之间的关联如何解释？

2018-12-28 MedSci MedSci原创

近日，国际杂志《Diabetic Med》上在线发表一项关于巨细胞病毒血清阳性与2型糖尿病之间的关联的国家健康与营养调查研究。评估来自国家健康和营养调查的6664名参与者中巨细胞病毒与2型糖尿病之间的关联。研究人员使用了1999年至2004年参加国家健康和营养调查的20-49岁成人的现有数据。使用巨细胞病毒特异性免疫球蛋白G抗体测定巨细胞病毒状态。通过自我报告或≥7mmol/l的血浆空

近日，国际杂志《Diabetic Med》上在线发表一项关于巨细胞病毒血清阳性与2型糖尿病之间的关联的国家健康与营养调查研究。评估来自国家健康和营养调查的6664名参与者中巨细胞病毒与2型糖尿病之间的关联。

研究人员使用了1999年至2004年参加国家健康和营养调查的20-49岁成人的现有数据。使用巨细胞病毒特异性免疫球蛋白G抗体测定巨细胞病毒状态。通过自我报告或≥7mmol/l的血浆空腹血糖评估普遍存在的2型糖尿病。在校正年龄，性别，种族/民族，吸烟状况，教育，BMI和身体活动后，使用Logistic回归模型评估2型糖尿病与巨细胞病毒血清阳性之间的关联。

在单变量模型中，2型糖尿病的原始几率中巨细胞病毒血清阳性较细胞病毒血清阴性的患者高47％。在校正年龄和其他协变量后，这种关联减弱并且不再显著：对于巨细胞病毒血清反应阳性和阴性的个体糖的尿病的优势比为1.09（95％CI 0.71-1.66）。

研究表明，巨细胞病毒和2型糖尿病之间的关联可以通过年龄和糖尿病的其他危险因素来解释。

原始出处：

L. Schmidt，H. H. Nelson，B. Thyagarajan，et al. Association between cytomegalovirus seropositivity and Type 2 diabetes is explained by age and other demographic characteristics: the National Health and Nutrition Examination Survey

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2019-10-01 ms5439512287675881

#BET#

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2019-05-26 ms9608593228839890

#DIA#

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2019-06-23 chenzhuanggui

#Diabetic#

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2018-12-30 wwzzly

#巨细胞#

30 0
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2018-12-30 仁者大医

#血清阳性#

33 0
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2018-12-30 ms3994565386320060

#Med#

15 0
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2018-12-28 misszhang

谢谢MedSci提供最新的资讯

43 0

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Diabetic Med：巨细胞病毒血清阳性与2型糖尿病之间的关联如何解释？

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