JAHA:主动脉缩窄成人卒中发病年龄分析!

2018-06-02 xing.T MedSci原创

由此可见,CoA患者的缺血性卒中和出血性卒中的发生年龄明显低于一般人群。

主动脉缩窄(CoA)修复的成人与一般人群相比长期存活率有所降低。近日,心血管疾病领域权威杂志JAHA上发表了一篇研究文章,该研究旨在明确CoA是否与早发缺血性卒中和出血性卒中独立相关。

这是一个横断面研究,该研究利用了2005年到2014年期间的全国住院样本数据库。研究人员假设CoA患者比一般人群在发生因缺血性和出血性卒中而住院的年龄更小。为了检验这个假设,研究人员采用简单和多变量加权线性回归比较了患有或没有CoA患者的卒中年龄。

在4894582名脑卒中出院患者中,207名患者诊断为CoA。CoA患者的卒中发生年龄显著低于没有CoA的患者:对于所有类型脑卒中患者要年轻18.9岁(P<0.001),比缺血性卒中患者年轻15.9岁(P<0.001),比出血性脑卒中年轻28.5岁(P<0.001),在调整潜在混杂因素后。有和无CoA患者的缺血性卒中比例无显著差异(79.2% vs. 83%,P=0.50)。然而,相比于无CoA患者,CoA患者蛛网膜下腔出血比例较高(分别为11.8% vs. 4.8%,P=0.039)。在有出血性脑卒中的患者中,CoA患者未破裂颅内动脉瘤的患病率高于无CoA患者(23.3% vs. 2.5%,P=0.002)。

由此可见,CoA患者的缺血性卒中和出血性卒中的发生年龄明显低于一般人群。

原始出处:

Sarah S. Pickard.et al. Stroke in Adults With Coarctation of the Aorta: A National Population‐Based Study.JAHA.2018. https://doi.org/10.1161/JAHA.118.009072

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    2018-06-04 zhaohui6731
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    2018-06-02 健健

    卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1689954, encodeId=6512168995433, content=<a href='/topic/show?id=4dea232255a' target=_blank style='color:#2F92EE;'>#主动脉缩窄#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23225, encryptionId=4dea232255a, topicName=主动脉缩窄)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=55683, createdName=仁医06, createdTime=Tue Feb 19 13:31:00 CST 2019, time=2019-02-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1267835, encodeId=a379126e83587, content=<a href='/topic/show?id=922f21183d' target=_blank style='color:#2F92EE;'>#AHA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2118, encryptionId=922f21183d, topicName=AHA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bf3d82, createdName=zhaohui6731, createdTime=Mon Jun 04 05:31:00 CST 2018, time=2018-06-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1415319, encodeId=a6be141531912, content=<a href='/topic/show?id=04812314540' target=_blank style='color:#2F92EE;'>#主动脉#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23145, encryptionId=04812314540, topicName=主动脉)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=77603112682, createdName=circumcision, createdTime=Mon Jun 04 05:31:00 CST 2018, time=2018-06-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1620331, encodeId=4d3a1620331a8, content=<a href='/topic/show?id=6a2f3e9132a' target=_blank style='color:#2F92EE;'>#发病年龄#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37913, encryptionId=6a2f3e9132a, topicName=发病年龄)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=973220095439, createdName=showtest, createdTime=Mon Jun 04 05:31:00 CST 2018, time=2018-06-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1026063, encodeId=0fc71026063fe, content=卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=健健, createdTime=Sat Jun 02 17:31:00 CST 2018, time=2018-06-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=320874, encodeId=4cf93208e4c7, content=好文章.学习了., beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=60791943465, createdName=1e0f8808m18(暂无匿称), createdTime=Sat Jun 02 16:17:02 CST 2018, time=2018-06-02, status=1, ipAttribution=)]
    2018-06-02 1e0f8808m18(暂无匿称)

    好文章.学习了.

    0

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