Immun Inflamm Dis:永久过敏性鼻炎患者中,MP-AzeFlu治疗效果分析

2018-10-25 AlexYang MedSci原创

大多数过敏性鼻炎(AR)患者患有中度到重度以及永久性症状。MP-AzeFlu组合鼻内盐酸氮卓斯汀(AZE)和氟替卡松丙酸酯(FP)可以作为一种新的治疗方法来治疗AR。最近,有研究人员在一个前瞻性的和非介入性研究中探索和评估了MP-AzeFlu在减轻AR症状严重度中的效果。研究人员发现,那些使用MP-AzeFlu的患者的VAS评分从开始的73.4mm(SD.20.3)快速降低到了第28天的31.5m

大多数过敏性鼻炎(AR)患者患有中度到重度以及永久性症状。MP-AzeFlu组合鼻内盐酸氮卓斯汀(AZE)和氟替卡松丙酸酯(FP)可以作为一种新的治疗方法来治疗AR。最近,有研究人员在一个前瞻性的和非介入性研究中探索和评估了MP-AzeFlu在减轻AR症状严重度中的效果。

研究人员发现,那些使用MP-AzeFlu的患者的VAS评分从开始的73.4mm(SD.20.3)快速降低到了第28天的31.5mm(SD, 25.0) (P<0.0001)和第42天的28.1mm(SD, 24.1)(P<0.0001)。平均来讲,患者在接受治疗的前7天,临床相关的VAS评分减少了50mm。另外,总的内窥镜评分从基线时间点的7.5mm(SD, 3.1)减少到了第28天的3.5mm(SD, 2.5)。内窥镜检查中的重度水肿的发生率从基线时间的53.1%下降到了第28天的3.8%。研究人员同样观察到了粘液排出的减少(从28.3%到4.8%)和重度红肿的减少(从34.9%到0%)的效果。

最后,研究人员指出,MP-AzeFlu为PER提供了有效的和快速的症状控制。症状在第一天就有所改善并持续到了第42天,并且鼻粘膜在28天治疗后也出现改善。最后,研究人员指出,他们的结果表明了MP-AzeFlu治疗效果的安全性,并且治疗效果要比阶段3临床研究的结果更好。

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    2019-01-14 lxg951
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    2018-10-27 xiaoyeshuang
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    2018-10-25 内科新手

    谢谢梅斯提供这么好的信息,学到很多

    0

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    2018-10-25 CHANGE

    疗效只是效果的众多方面之一,还要看对患者的获益,包括生活质量等因素共同决定效果的

    0

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