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Am J Clin Nutr：低血糖负荷或富含谷物纤维的饮食能减重！

2017-08-22 徐晓涵 环球医学

低血糖负荷富含谷物纤维饮食减重
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2017年8月，发表在《Am J Clin Nutr》的一项由荷兰、法国和丹麦科学家进行的研究，发现超重患者可通过消耗低血糖负荷或富含纤维和全谷物的饮食而成功减重和维持体重

2017年8月，发表在《Am J Clin Nutr》的一项由荷兰、法国和丹麦科学家进行的研究，发现超重患者可通过消耗低血糖负荷或富含纤维和全谷物的饮食而成功减重和维持体重

背景：对减重和维持体重来说，哪种饮食是最优的存在争议，同时也意味着没有适合所有患者的饮食。

目的：研究人员对空腹血糖（FPG）浓度和空腹胰岛素（FI）浓度作为成功减重和维持体重的预后标志物进行了研究，通过不同的血糖负荷或不同的纤维和全谷物含量的饮食，对超重参与者进行了3次随机试验。

设计：8周的减重后，DiOGene（饮食、肥胖和基因）试验中的参与者进行了26周的自由饮食，该饮食具有较高或较低的血糖负荷。通过对丹麦儿童进行的健康新北欧饮食（OPUS）超市干预（SHOPUS）试验，最佳福利、发育和健康试验中的参与者进行了26周的新北欧饮食或对照饮食，其中新北欧饮食富含纤维和全谷物。NUGENOB（肥胖者营养基因相互作用）试验中的参与者进行了10周的低热量低脂肪和高碳水化合物或高脂肪和低碳水化合物的饮食。基于治疗前的FPG，参与者分为血糖正常（FPG＜5.6mmol/L）、糖尿病前期（FPG为5.6~6.9mmol/L）、糖尿病（FPG≥7.0mmol/L）。治疗前，FPG和FI饮食影响的改变通过混合线性模型进行检测。

结果：DiOGene试验中，高血糖负荷饮食的糖尿病前期个体比低血糖负荷的个体，平均增重大于5.83kg（95% CI，3.34~8.32；P＜0.001），而血糖正常的个体平均增重大于1.44kg（95% CI，0.48~2.41；P=0.003）（组间平均差，4.39kg（1.76~7.02）；P=0.001）。SHOPUS中，新北欧饮食的糖尿病前期个体比对照饮食的个体平均减重大于6.04kg（95% CI，4.05~8.02；P＜0.001），而血糖正常的个体平均减重大于2.20kg（95% CI，1.21~3.18；P＜0.001）（组间平均差，3.84kg[1.62~6.06]；P=0.001）。NUGENOB中，高脂和低碳水化合物饮食的糖尿病个体比低脂和高碳水化合物饮食的个体平均减重大于2.04kg（95% CI，-0.20~4.28；P=0.07），而低脂和高碳水化合物饮食的血糖正常个体平均减重大于0.43kg（95% CI，0.03~0.83；P=0.03）（组间平均差，2.47kg[0.20~4.75]；P=0.03）。加入FI会加强这些相关性。

结论：治疗前FPG升高表明，超重患者可通过消耗低血糖负荷或富含纤维和全谷物的饮食而成功减重并维持体重。

原始出处：
Hjorth MF, Ritz C, Blaak EE, et al.Pretreatment fasting plasma glucose and insulin modify dietary weight loss success: results from 3 randomized clinical trials.Am J Clin Nutr. 2017 Aug;106(2):499-505. doi: 10.3945/ajcn.117.155200. Epub 2017 Jul 5.

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    2017-08-24 heli0118

    #血糖负荷#

    0

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    2017-12-02 licz0435

    #谷物#

    0

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    2017-09-17 186****0580(小山羊）

    学习了谢谢了

    0

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    2017-08-23 184****9840

    学习了谢谢分享

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=2041014, encodeId=620b20410145e, content=<a href='/topic/show?id=6ef4898581e' target=_blank style='color:#2F92EE;'>#血糖负荷#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89858, encryptionId=6ef4898581e, topicName=血糖负荷)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=21015, createdName=heli0118, createdTime=Thu Aug 24 00:56:00 CST 2017, time=2017-08-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1745011, encodeId=996b1e450115f, content=<a href='/topic/show?id=c39d921e332' target=_blank style='color:#2F92EE;'>#谷物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=92173, encryptionId=c39d921e332, topicName=谷物)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=113b35497390, createdName=licz0435, createdTime=Sat Dec 02 05:56:00 CST 2017, time=2017-12-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=244933, encodeId=cc9124493380, content=学习了谢谢了, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLPeNmuNF9ibgMfMOAs7Iic5MpiaU8RLmRH67xCKuk5wzfhb7G4ib7ia6z9lrnsTicj1nAUfEOMecZDtvvu/0, createdBy=d7f91939785, createdName=186****0580(小山羊）, createdTime=Sun Sep 17 09:04:20 CST 2017, time=2017-09-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=236209, encodeId=65a1236209aa, content=学习了谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5Kzuf9u71gZhPYMiajRtENwicoAABeQtfXOlic8ibhYSy6DvJZWUDVtjRvTfqBffr1XJ6JLtFB5kHicthl/0, createdBy=d41c2055892, createdName=184****9840, createdTime=Wed Aug 23 06:48:16 CST 2017, time=2017-08-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=236057, encodeId=3adc23605ebb, content=不错的.学习了.谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NdqKgfW3nMpOkC3jXxiaW2po0PtglY5ZuVjERqKADW4HyMI8bcZXWlKgH7tEP9ULBoBzuQMibia4pr1s9rQPqLvqQJ/0, createdBy=e8c02060444, createdName=中医痴, createdTime=Tue Aug 22 17:01:09 CST 2017, time=2017-08-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=236049, encodeId=691723604969, content=学了........., beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4Neru1qt53a14aACuSzg3TZhkTcsPYVibyHibhTZ5L4k9qIBWiaej4lgomIsGptf8N16E4mTuIq2DVdJXjPjmwZKrLib/0, createdBy=5a0f2055853, createdName=135****7952平儿, createdTime=Tue Aug 22 16:33:14 CST 2017, time=2017-08-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=236041, encodeId=2a4b236041e5, content=治疗前FPG升高表明.超重患者可通过消耗低血糖负荷或富含纤维和全谷物的饮食而成功减重并维持体重., beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7cJ6ejWUr2nIia8qOvAKNdLHr32Df6G8iaoaOx6pHaoiacwp26DaslxZHCGbibZhhCGven4rvmWP60GahtzgFjgCjR/0, createdBy=6b111703011, createdName=有备才能无患, createdTime=Tue Aug 22 16:07:34 CST 2017, time=2017-08-22, status=1, ipAttribution=)]
    2017-08-22 中医痴

    不错的.学习了.谢谢分享!

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=2041014, encodeId=620b20410145e, content=<a href='/topic/show?id=6ef4898581e' target=_blank style='color:#2F92EE;'>#血糖负荷#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89858, encryptionId=6ef4898581e, topicName=血糖负荷)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=21015, createdName=heli0118, createdTime=Thu Aug 24 00:56:00 CST 2017, time=2017-08-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1745011, encodeId=996b1e450115f, content=<a href='/topic/show?id=c39d921e332' target=_blank style='color:#2F92EE;'>#谷物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=92173, encryptionId=c39d921e332, topicName=谷物)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=113b35497390, createdName=licz0435, createdTime=Sat Dec 02 05:56:00 CST 2017, time=2017-12-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=244933, encodeId=cc9124493380, content=学习了谢谢了, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLPeNmuNF9ibgMfMOAs7Iic5MpiaU8RLmRH67xCKuk5wzfhb7G4ib7ia6z9lrnsTicj1nAUfEOMecZDtvvu/0, createdBy=d7f91939785, createdName=186****0580(小山羊）, createdTime=Sun Sep 17 09:04:20 CST 2017, time=2017-09-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=236209, encodeId=65a1236209aa, content=学习了谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5Kzuf9u71gZhPYMiajRtENwicoAABeQtfXOlic8ibhYSy6DvJZWUDVtjRvTfqBffr1XJ6JLtFB5kHicthl/0, createdBy=d41c2055892, createdName=184****9840, createdTime=Wed Aug 23 06:48:16 CST 2017, time=2017-08-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=236057, encodeId=3adc23605ebb, content=不错的.学习了.谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NdqKgfW3nMpOkC3jXxiaW2po0PtglY5ZuVjERqKADW4HyMI8bcZXWlKgH7tEP9ULBoBzuQMibia4pr1s9rQPqLvqQJ/0, createdBy=e8c02060444, createdName=中医痴, createdTime=Tue Aug 22 17:01:09 CST 2017, time=2017-08-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=236049, encodeId=691723604969, content=学了........., beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4Neru1qt53a14aACuSzg3TZhkTcsPYVibyHibhTZ5L4k9qIBWiaej4lgomIsGptf8N16E4mTuIq2DVdJXjPjmwZKrLib/0, createdBy=5a0f2055853, createdName=135****7952平儿, createdTime=Tue Aug 22 16:33:14 CST 2017, time=2017-08-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=236041, encodeId=2a4b236041e5, content=治疗前FPG升高表明.超重患者可通过消耗低血糖负荷或富含纤维和全谷物的饮食而成功减重并维持体重., beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7cJ6ejWUr2nIia8qOvAKNdLHr32Df6G8iaoaOx6pHaoiacwp26DaslxZHCGbibZhhCGven4rvmWP60GahtzgFjgCjR/0, createdBy=6b111703011, createdName=有备才能无患, createdTime=Tue Aug 22 16:07:34 CST 2017, time=2017-08-22, status=1, ipAttribution=)]
    2017-08-22 135****7952平儿

    学了.........

    0

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    2017-08-22 有备才能无患

    治疗前FPG升高表明.超重患者可通过消耗低血糖负荷或富含纤维和全谷物的饮食而成功减重并维持体重.

    0