J Periodontol:牙周炎或与偏头痛的进展相关

2018-03-11 MedSci MedSci原创

本项横断面研究旨在评估慢性牙周炎(CP)对慢性偏头痛(CM)患者血清降钙素原(proCT)水平的影响。 根据CM和牙周参数的临床特征,将138名受试者分为4组:系统和牙周健康个体(n = 37),系统健康和CP患者(n = 19),CM和牙周健康患者(n = 34)和CM + CP患者(n = 48)。收集人口统计学、神经学、临床数据以及全口牙周病记录。采集偏头痛发作期间参与者的血液样本确定Pro

本项横断面研究旨在评估慢性牙周炎(CP)对慢性偏头痛(CM)患者血清降钙素原(proCT)水平的影响。

根据CM和牙周参数的临床特征,将138名受试者分为4组:系统和牙周健康个体(n = 37),系统健康和CP患者(n = 19),CM和牙周健康患者(n = 34)和CM + CP患者(n = 48)。收集人口统计学、神经学、临床数据以及全口牙周病记录。采集偏头痛发作期间参与者的血液样本确定ProCT和高敏C反应蛋白(hs-CRP)的血清水平。

结果显示,与全身和牙周健康组(0.029±0.019 ng/mL)、CM组(0.041±0.002 ng/mL)及CP组(0.041±0.002 ng/mL)相比,CP+CM组患者血清proCT的水平明显升高(0.034±0.014ng/mL)(p <0.001)。组间hs-CRP无明显差异(p = 0.081)。多元线性回归分析显示CP与CM患者proCT的水平升高相关(R2 = 0.293,p <0.001)。

综上所述,该研究结果表明,CP可促进血清proCT水平升高,与CM无关。这些发现表明,CP可能在偏头痛慢性化中起作用。

原始出处:


Leira Y, Ameijeira P, et al., High serum procalcitonin levels in patients with periodontitis and chronic migraine. J Periodontol. 2018 Mar 9. doi: 10.1002/JPER.17-0603. [Epub ahead of print]

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    2019-01-03 feather89
  2. [GetPortalCommentsPageByObjectIdResponse(id=1727145, encodeId=2ceb1e2714583, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Thu Jan 03 14:42:00 CST 2019, time=2019-01-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1450821, encodeId=1993145082136, content=<a href='/topic/show?id=f0476e49582' target=_blank style='color:#2F92EE;'>#牙周#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67495, encryptionId=f0476e49582, topicName=牙周)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ab585558129, createdName=liuyong2982, createdTime=Tue Mar 13 09:42:00 CST 2018, time=2018-03-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=295225, encodeId=570029522553, content=了解一下.谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/12/23/2f51002e1349ccda5be11c1eea1e1e60.jpg, createdBy=a22097948, createdName=天地飞扬, createdTime=Sun Mar 11 19:19:38 CST 2018, time=2018-03-11, status=1, ipAttribution=)]
    2018-03-13 liuyong2982
  3. [GetPortalCommentsPageByObjectIdResponse(id=1727145, encodeId=2ceb1e2714583, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Thu Jan 03 14:42:00 CST 2019, time=2019-01-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1450821, encodeId=1993145082136, content=<a href='/topic/show?id=f0476e49582' target=_blank style='color:#2F92EE;'>#牙周#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67495, encryptionId=f0476e49582, topicName=牙周)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ab585558129, createdName=liuyong2982, createdTime=Tue Mar 13 09:42:00 CST 2018, time=2018-03-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=295225, encodeId=570029522553, content=了解一下.谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/12/23/2f51002e1349ccda5be11c1eea1e1e60.jpg, createdBy=a22097948, createdName=天地飞扬, createdTime=Sun Mar 11 19:19:38 CST 2018, time=2018-03-11, status=1, ipAttribution=)]
    2018-03-11 天地飞扬

    了解一下.谢谢分享!

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