JAHA:中国山东省高钠摄入导致的心血管疾病死亡人数

2018-12-19 xing.T MedSci原创

由此可见,2011年山东省25至69岁的成年人中,近20%的CVD死亡可归因于高钠摄入量所致的收缩压升高效应。人群减少钠摄入的潜在益处是相当大的。

高钠摄入会升高血压,从而引起血管疾病(CVD)。中国北方的钠摄入量很高,包括山东省,目前正在山东进行SMASH(山东省卫生厅钠和高血压行动)研究。

近日,血管疾病领域权威杂志JAHA上发表了一篇研究文章,研究人员从2011年SMASH研究基线调查中收集了通过24小时尿排泄测定的钠摄入量以及血压值,该调查使用多阶段分层整群随机抽样方法在山东20个县/区进行。研究人员在同一年从山东死亡登记系统(SDRS)中得到了病因特异性死亡率,并使用人口归因分数来估计由于高钠摄入量(通过升高收缩压来介导)导致的年度心血管疾病死亡,以及达到不同的减钠目标所避免的CVD死亡情况。

总体而言,25至69岁成人的死亡率为16100(95%不确定区间为11000-22600),其中缺血性心脏病为5600人(4000-6500),卒中为9000人(6700-11600),可归因于2011年较高的钠摄入量(2000mg/天或5.0g/天盐作为对照),占心血管疾病死亡总数的19.9%(13.7-25.0%)。如果钠摄入量从2011年的基线减少到3500mg/天、4000mg/天或减少30%,那么CVD死亡的益处相当大,分别减少8800人(6400-13600)、6700(4900-11600)和8500(6000-10800)。

由此可见,2011年山东省25至69岁的成年人中,近20%的CVD死亡可归因于高钠摄入量所致的收缩压升高效应。人群减少钠摄入的潜在益处是相当大的。

原始出处:

Jiyu Zhang.et al.Cardiovascular Diseases Deaths Attributable to High Sodium Intake in Shandong Province, China.JAHA.2018.https://www.ahajournals.org/doi/10.1161/JAHA.118.010737

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    2018-12-21 zhaohui6731
  5. [GetPortalCommentsPageByObjectIdResponse(id=1954964, encodeId=e3af195496418, content=<a href='/topic/show?id=b72896446f3' target=_blank style='color:#2F92EE;'>#钠摄入#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=96446, encryptionId=b72896446f3, topicName=钠摄入)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=55683, createdName=仁医06, createdTime=Mon Jun 17 01:30:00 CST 2019, time=2019-06-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1967526, encodeId=2d17196e52653, content=<a href='/topic/show?id=7fe36335360' target=_blank style='color:#2F92EE;'>#死亡人数#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=63353, encryptionId=7fe36335360, topicName=死亡人数)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c39f145, createdName=smlt2008, createdTime=Thu Oct 10 14:30:00 CST 2019, time=2019-10-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1908112, encodeId=de041908112cd, content=<a href='/topic/show?id=96334e74810' target=_blank style='color:#2F92EE;'>#山东省#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=47748, encryptionId=96334e74810, topicName=山东省)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=930e243, createdName=dingxiaobo, createdTime=Tue Apr 16 12:30:00 CST 2019, time=2019-04-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1268010, encodeId=377112680107e, content=<a href='/topic/show?id=922f21183d' target=_blank style='color:#2F92EE;'>#AHA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2118, encryptionId=922f21183d, topicName=AHA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bf3d82, createdName=zhaohui6731, createdTime=Fri Dec 21 13:30:00 CST 2018, time=2018-12-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1498511, encodeId=48ca1498511a2, content=<a href='/topic/show?id=bb6f89e145a' target=_blank style='color:#2F92EE;'>#血管疾病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89714, encryptionId=bb6f89e145a, topicName=血管疾病)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ccb99370406, createdName=andy2090, createdTime=Fri Dec 21 13:30:00 CST 2018, time=2018-12-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=355944, encodeId=c96a355944f6, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmhead/Q3auHgzwzM6P57Bs8gOPaY1cQP9lIia0lmZOEXraGaoicqNToIslXDKw/0, createdBy=7a041951742, createdName=衣带渐宽, createdTime=Thu Dec 20 16:41:06 CST 2018, time=2018-12-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=355927, encodeId=4df335592e5b, content=数量触目惊心, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6ef781002, createdName=topnew, createdTime=Thu Dec 20 10:31:13 CST 2018, time=2018-12-20, status=1, ipAttribution=)]
  6. [GetPortalCommentsPageByObjectIdResponse(id=1954964, encodeId=e3af195496418, content=<a href='/topic/show?id=b72896446f3' target=_blank style='color:#2F92EE;'>#钠摄入#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=96446, encryptionId=b72896446f3, topicName=钠摄入)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=55683, createdName=仁医06, createdTime=Mon Jun 17 01:30:00 CST 2019, time=2019-06-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1967526, encodeId=2d17196e52653, content=<a href='/topic/show?id=7fe36335360' target=_blank style='color:#2F92EE;'>#死亡人数#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=63353, encryptionId=7fe36335360, topicName=死亡人数)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c39f145, createdName=smlt2008, createdTime=Thu Oct 10 14:30:00 CST 2019, time=2019-10-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1908112, encodeId=de041908112cd, content=<a href='/topic/show?id=96334e74810' target=_blank style='color:#2F92EE;'>#山东省#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=47748, encryptionId=96334e74810, topicName=山东省)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=930e243, createdName=dingxiaobo, createdTime=Tue Apr 16 12:30:00 CST 2019, time=2019-04-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1268010, encodeId=377112680107e, content=<a href='/topic/show?id=922f21183d' target=_blank style='color:#2F92EE;'>#AHA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2118, encryptionId=922f21183d, topicName=AHA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bf3d82, createdName=zhaohui6731, createdTime=Fri Dec 21 13:30:00 CST 2018, time=2018-12-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1498511, encodeId=48ca1498511a2, content=<a href='/topic/show?id=bb6f89e145a' target=_blank style='color:#2F92EE;'>#血管疾病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89714, encryptionId=bb6f89e145a, topicName=血管疾病)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ccb99370406, createdName=andy2090, createdTime=Fri Dec 21 13:30:00 CST 2018, time=2018-12-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=355944, encodeId=c96a355944f6, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmhead/Q3auHgzwzM6P57Bs8gOPaY1cQP9lIia0lmZOEXraGaoicqNToIslXDKw/0, createdBy=7a041951742, createdName=衣带渐宽, createdTime=Thu Dec 20 16:41:06 CST 2018, time=2018-12-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=355927, encodeId=4df335592e5b, content=数量触目惊心, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6ef781002, createdName=topnew, createdTime=Thu Dec 20 10:31:13 CST 2018, time=2018-12-20, status=1, ipAttribution=)]
    2018-12-20 衣带渐宽

    学习

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=1954964, encodeId=e3af195496418, content=<a href='/topic/show?id=b72896446f3' target=_blank style='color:#2F92EE;'>#钠摄入#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=96446, encryptionId=b72896446f3, topicName=钠摄入)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=55683, createdName=仁医06, createdTime=Mon Jun 17 01:30:00 CST 2019, time=2019-06-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1967526, encodeId=2d17196e52653, content=<a href='/topic/show?id=7fe36335360' target=_blank style='color:#2F92EE;'>#死亡人数#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=63353, encryptionId=7fe36335360, topicName=死亡人数)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c39f145, createdName=smlt2008, createdTime=Thu Oct 10 14:30:00 CST 2019, time=2019-10-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1908112, encodeId=de041908112cd, content=<a href='/topic/show?id=96334e74810' target=_blank style='color:#2F92EE;'>#山东省#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=47748, encryptionId=96334e74810, topicName=山东省)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=930e243, createdName=dingxiaobo, createdTime=Tue Apr 16 12:30:00 CST 2019, time=2019-04-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1268010, encodeId=377112680107e, content=<a href='/topic/show?id=922f21183d' target=_blank style='color:#2F92EE;'>#AHA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2118, encryptionId=922f21183d, topicName=AHA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bf3d82, createdName=zhaohui6731, createdTime=Fri Dec 21 13:30:00 CST 2018, time=2018-12-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1498511, encodeId=48ca1498511a2, content=<a href='/topic/show?id=bb6f89e145a' target=_blank style='color:#2F92EE;'>#血管疾病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89714, encryptionId=bb6f89e145a, topicName=血管疾病)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ccb99370406, createdName=andy2090, createdTime=Fri Dec 21 13:30:00 CST 2018, time=2018-12-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=355944, encodeId=c96a355944f6, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmhead/Q3auHgzwzM6P57Bs8gOPaY1cQP9lIia0lmZOEXraGaoicqNToIslXDKw/0, createdBy=7a041951742, createdName=衣带渐宽, createdTime=Thu Dec 20 16:41:06 CST 2018, time=2018-12-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=355927, encodeId=4df335592e5b, content=数量触目惊心, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6ef781002, createdName=topnew, createdTime=Thu Dec 20 10:31:13 CST 2018, time=2018-12-20, status=1, ipAttribution=)]
    2018-12-20 topnew

    数量触目惊心

    0