Eur Heart J:体重和体重变化与房颤风险

2019-06-18 xing.T 网络

由此可见,长期肥胖和BMI变化与AF风险有关。即使在考虑到近期的BMI之后,生命早期的肥胖和体重增加随着时间的推移对AF发生发展产生累积效应。

尽管肥胖与心房颤动(AF)的风险有关,但长期肥胖、近期肥胖和体重变化与整个成年期AF风险的相关性尚不确定。

近日,心血管领域权威杂志Eur Heart J上发表了一篇研究文章,研究人员进行了一项队列研究,其中纳入了15214名参与者。该队列创建于2006年至2008年(基线),随访AF事件直至2015年。在基线时直接测量体重和身高。从基线前10年、20年和40年进行的测量中回顾性地检索先前体重和身高的数据。研究人员计算了随时间变化的平均体重指数(BMI)和体重变化。

在随访期间,1149名参与者发展为AF患者。与正常体重相比,对于平均BMI为25.0-29.9 kg/m2的参与者多变量校正风险比为1.2(95%置信区间为1.0-1.4),,平均BMI≥30kg/m2的参与者为1.6(1.2-2.0)。在调整最近的BMI后,平均B​​MI与AF风险的关联仅略微减弱。相比之下,在调整生命早期的平均BMI后,目前的BMI与AF风险相关性并不密切。与稳定的BMI相比,BMI减少和增加都与AF风险增加有关。在调整最近的BMI后,BMI增加与AF风险的关联基本没有变化,而BMI减少与AF风险的关联减弱。

由此可见,长期肥胖和BMI变化与AF风险有关。即使在考虑到近期的BMI之后,生命早期的肥胖和体重增加随着时间的推移对AF发生发展产生累积效应。 

原始出处:

Tingting Feng.et al.Weight and weight change and risk of atrial fibrillation: the HUNT study.Eur Heart J. https://doi.org/10.1093/eurheartj/ehz390

本文系梅斯医学(MedSci)原创编译整理,转载需授权!

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (4)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=2079422, encodeId=f5af20e942219, content=<a href='/topic/show?id=7f7d266897b' target=_blank style='color:#2F92EE;'>#体重变化#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26689, encryptionId=7f7d266897b, topicName=体重变化)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e0a1165, createdName=jiangfeng5067, createdTime=Fri Jul 12 21:06:00 CST 2019, time=2019-07-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1357211, encodeId=f21e135e211ed, content=<a href='/topic/show?id=b0702e84b9' target=_blank style='color:#2F92EE;'>#ART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2784, encryptionId=b0702e84b9, topicName=ART)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Thu Jun 20 12:06:00 CST 2019, time=2019-06-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1532019, encodeId=b35e15320195a, content=<a href='/topic/show?id=b0885428229' target=_blank style='color:#2F92EE;'>#房颤风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=54282, encryptionId=b0885428229, topicName=房颤风险)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=6ea612304943, createdName=whmdzju, createdTime=Thu Jun 20 12:06:00 CST 2019, time=2019-06-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1563108, encodeId=cf79156310887, content=<a href='/topic/show?id=f69d864413' target=_blank style='color:#2F92EE;'>#HEART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8644, encryptionId=f69d864413, topicName=HEART)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=80d715270048, createdName=slcumt, createdTime=Thu Jun 20 12:06:00 CST 2019, time=2019-06-20, status=1, ipAttribution=)]
  2. [GetPortalCommentsPageByObjectIdResponse(id=2079422, encodeId=f5af20e942219, content=<a href='/topic/show?id=7f7d266897b' target=_blank style='color:#2F92EE;'>#体重变化#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26689, encryptionId=7f7d266897b, topicName=体重变化)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e0a1165, createdName=jiangfeng5067, createdTime=Fri Jul 12 21:06:00 CST 2019, time=2019-07-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1357211, encodeId=f21e135e211ed, content=<a href='/topic/show?id=b0702e84b9' target=_blank style='color:#2F92EE;'>#ART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2784, encryptionId=b0702e84b9, topicName=ART)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Thu Jun 20 12:06:00 CST 2019, time=2019-06-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1532019, encodeId=b35e15320195a, content=<a href='/topic/show?id=b0885428229' target=_blank style='color:#2F92EE;'>#房颤风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=54282, encryptionId=b0885428229, topicName=房颤风险)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=6ea612304943, createdName=whmdzju, createdTime=Thu Jun 20 12:06:00 CST 2019, time=2019-06-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1563108, encodeId=cf79156310887, content=<a href='/topic/show?id=f69d864413' target=_blank style='color:#2F92EE;'>#HEART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8644, encryptionId=f69d864413, topicName=HEART)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=80d715270048, createdName=slcumt, createdTime=Thu Jun 20 12:06:00 CST 2019, time=2019-06-20, status=1, ipAttribution=)]
    2019-06-20 zhaojie88
  3. [GetPortalCommentsPageByObjectIdResponse(id=2079422, encodeId=f5af20e942219, content=<a href='/topic/show?id=7f7d266897b' target=_blank style='color:#2F92EE;'>#体重变化#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26689, encryptionId=7f7d266897b, topicName=体重变化)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e0a1165, createdName=jiangfeng5067, createdTime=Fri Jul 12 21:06:00 CST 2019, time=2019-07-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1357211, encodeId=f21e135e211ed, content=<a href='/topic/show?id=b0702e84b9' target=_blank style='color:#2F92EE;'>#ART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2784, encryptionId=b0702e84b9, topicName=ART)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Thu Jun 20 12:06:00 CST 2019, time=2019-06-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1532019, encodeId=b35e15320195a, content=<a href='/topic/show?id=b0885428229' target=_blank style='color:#2F92EE;'>#房颤风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=54282, encryptionId=b0885428229, topicName=房颤风险)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=6ea612304943, createdName=whmdzju, createdTime=Thu Jun 20 12:06:00 CST 2019, time=2019-06-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1563108, encodeId=cf79156310887, content=<a href='/topic/show?id=f69d864413' target=_blank style='color:#2F92EE;'>#HEART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8644, encryptionId=f69d864413, topicName=HEART)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=80d715270048, createdName=slcumt, createdTime=Thu Jun 20 12:06:00 CST 2019, time=2019-06-20, status=1, ipAttribution=)]
  4. [GetPortalCommentsPageByObjectIdResponse(id=2079422, encodeId=f5af20e942219, content=<a href='/topic/show?id=7f7d266897b' target=_blank style='color:#2F92EE;'>#体重变化#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26689, encryptionId=7f7d266897b, topicName=体重变化)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e0a1165, createdName=jiangfeng5067, createdTime=Fri Jul 12 21:06:00 CST 2019, time=2019-07-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1357211, encodeId=f21e135e211ed, content=<a href='/topic/show?id=b0702e84b9' target=_blank style='color:#2F92EE;'>#ART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2784, encryptionId=b0702e84b9, topicName=ART)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Thu Jun 20 12:06:00 CST 2019, time=2019-06-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1532019, encodeId=b35e15320195a, content=<a href='/topic/show?id=b0885428229' target=_blank style='color:#2F92EE;'>#房颤风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=54282, encryptionId=b0885428229, topicName=房颤风险)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=6ea612304943, createdName=whmdzju, createdTime=Thu Jun 20 12:06:00 CST 2019, time=2019-06-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1563108, encodeId=cf79156310887, content=<a href='/topic/show?id=f69d864413' target=_blank style='color:#2F92EE;'>#HEART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8644, encryptionId=f69d864413, topicName=HEART)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=80d715270048, createdName=slcumt, createdTime=Thu Jun 20 12:06:00 CST 2019, time=2019-06-20, status=1, ipAttribution=)]
    2019-06-20 slcumt

相关资讯

BMJ:体重、血压以及吸烟教育对心血管风险的影响

研究认为BMI、收缩压和吸烟行为教育对降低心血管事件风险有重要作用

Journal of Internal Medicine:对于糖尿病前期,要使血糖恢复正常,控制血压和体重不可少

瑞典国家老龄化和护理研究对老年糖尿病前期患者进行了12年的随访,发现大多数人能保持稳定或恢复到正常血糖水平,只有三分之一的人发展至糖尿病或死亡。

Circulation:采用阿哌沙班预防血栓形成是否需要考虑患者体重?

指南提示:体重过重(>120kg)或过轻(<60kg)的患者慎用非维生素K拮抗剂类的口服抗凝药,因为缺乏这类人群的相关数据。ARISTOTLE试验是关于阿哌沙班(与华法林对比)降低房颤患者中风和其他血栓事件风险效应的随机性研究,共包含18201位受试者。现研究人员根据体重(≤60,>60–120,>120 kg)对ARISTOTLE试验的受试者重新分层,采用Cox回顾模型来

JAMA:孕前体重、孕期增重与母婴结局

研究发现,孕妇和婴儿不良结局的风险因妊娠体重增加和孕前体重范围不同而不同。

ADA 2019:8周内减重8%+长期维持,这么做能有效阻止糖尿病前期发展为糖尿病

2019年ADA年会上公布的PREVIEW研究提示,对于成人糖尿病前期患者,在8周期间,采用代餐首先使体重下降至少8%,然后采用包括饮食和体力活动在内的生活方式干预,可以明显减少新发2型糖尿病的发生。