JAMA刊登上海第一人民医院杨文艺博士为第-作者文章:夜间血压预测心血管事件风险有重要价值

2019-08-13 中国循环杂志 中国循环杂志

近日,上海市第一人民医院杨文艺博士以第一作者的身份在美国医学杂志(JAMA)发表文章称,与诊室血压相比,24小时动态血压监测中夜间和24小时平均血压的水平与心血管事件更为相关。JAMA刊登上海第一人民医院杨文艺博士为第一作者文章:夜间血压预测心血管事件风险有重要价值作者认为,夜间血压对心血管事件风险有重要预测价值,超过了日间血压。之前欧洲心脏杂志也有研究称,在血压的相关指标中,夜间收缩压高是预测心

近日,上海市第一人民医院杨文艺博士以第一作者的身份在美国医学杂志(JAMA)发表文章称,与诊室血压相比,24小时动态血压监测中夜间和24小时平均血压的水平与心血管事件更为相关。
JAMA刊登上海第一人民医院杨文艺博士为第一作者文章:夜间血压预测心<a class=

作者认为,夜间血压对心血管事件风险有重要预测价值,超过了日间血压。

之前欧洲心脏杂志也有研究称,在血压的相关指标中,夜间收缩压高是预测心血管事件中最重要的指标。平均睡眠收缩压值预测心血管病复合事件的效果,优于诊室血压和日间收缩压。

该文的通讯作者为比利时Jan A. Staessen教授,他在亚洲、欧洲及南美洲等地共建立有13个中心的动态血压人群数据库,跟踪随访总人数达13000多人。我国瑞金医院的王继光教授、李燕教授也参与了这项研究。

该研究显示,关于夜间收缩压水平,总死亡率HR为1.23(95%CI:1.17-1.28),心血管事件HR为1.36(95%CI:1.30~1.43)。24小时收缩压水平,总死亡率HR为1.22(95%CI:1.16~1.28),CV事件HR为1.45(95%CI:1.37~1.54)。通过校正其他血压指数,夜间和24小时SBP与主要结果的关系仍具有统计学意义[HR范围为:1.17(95%CI:1.10~1.25)到1.87(95%CI:1.62~2.16)]。

研究提示, 24小时和夜间血压可被认为是评估心血管病风险的最佳测量值,尽管统计学上,与其他血压指标相比,模型改善很小。

来源:

1、Wen-Yi Yang, et al. Association of Office and Ambulatory Blood Pressure With Mortality and Cardiovascular Outcomes. JAMA. August 6, 2019.

2、Ramón CHermida, et al. Asleep blood pressure: significant prognostic marker of vascular risk and therapeutic target for prevention.Eur Heart J. 2018.https://doi.org/10.1093/eurheartj/ehy475.

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