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Clinica Chimica Acta：变性人接受稳定激素治疗的血液学参考区间

2019-08-08 Gladiator MedSci原创

血液学参考区间变性人
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全血细胞计数<span lang="EN-US" style="font-size:12.0pt;mso-bidi-font-size:14.0pt;font-family:&quot;Calibri&quot;,&quot;sans-serif&quot;; mso-fareast-font-family:宋体;mso-bidi-font-family:&quot;Times New Roma

全血细胞计数(CBC)是病人护理的基础。一般来说，CBC各组分的几个正常值会因性别而异，因此，需要男性特异性和女性特异性参考区间来解释这些实验室结果。变性人通常会接受激素治疗来维持自己的性别，其血清激素浓度与正常性别者相似。对于包括血液学在内的任何实验室测量，还没有为跨性别男性和女性建立性别特异性参考区间。本研究为接受稳定激素治疗的变性人建立了临床相关的血液学参考区间。

研究人员从专门从事跨性别医疗的内科和初级保健诊所招募处方睾酮（n = 79）或雌激素（n = 93）≥12个月的健康变性人员。并评估他们的血红蛋白、红细胞压积、MCV、MCHC和RDWCV的浓度，以及红细胞、白细胞和血小板的计数。对其结果的解释参照了整体值的分布以及相对于血清雌二醇和总睾酮浓度。将计算出的参考区间与已建立的正常性别参考区间进行比较。

研究发现，无论血清激素浓度如何，个体给药的睾酮或雌激素的血液学参数在临床上与正常性别男性和女性无明显差异。

研究表明，接受稳定激素治疗的变性男性和女性的血液学参数应分别参照正常性别男性和女性参考范围进行评估，不需要同时进行性激素分析。护理人员可以利用这一观察结果来帮助解释跨性别者的血液学实验室价值。

原始出处：

Dina N.Greene,Gabrielle WinstonMcPherson,Hematology reference intervals for transgender adults on stable hormone therapy

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    2020-01-29 windight

    #CTA#

    0

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    2019-08-10 aliceclz

    #激素治疗#

    0

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    2019-08-10 marlenexl

    #变性人#

    0

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    2019-08-10 huangdf

    #变性#

    0

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    2019-08-10 hxq78318

    #血液学#

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1849685, encodeId=b69a18496857b, content=<a href='/topic/show?id=61815385aa' target=_blank style='color:#2F92EE;'>#CTA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5385, encryptionId=61815385aa, topicName=CTA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ec9955, createdName=windight, createdTime=Wed Jan 29 07:27:00 CST 2020, time=2020-01-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1307420, encodeId=4339130e420fd, content=<a href='/topic/show?id=b1d766836e4' target=_blank style='color:#2F92EE;'>#激素治疗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=66836, encryptionId=b1d766836e4, topicName=激素治疗)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=bfa6343, createdName=aliceclz, createdTime=Sat Aug 10 06:27:00 CST 2019, time=2019-08-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1372020, encodeId=811113e2020a6, content=<a href='/topic/show?id=7b4938129c3' target=_blank style='color:#2F92EE;'>#变性人#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=38129, encryptionId=7b4938129c3, topicName=变性人)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b53f332, createdName=marlenexl, createdTime=Sat Aug 10 06:27:00 CST 2019, time=2019-08-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1463688, encodeId=d1671463688bd, content=<a href='/topic/show?id=7d27381288e' target=_blank style='color:#2F92EE;'>#变性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=38128, encryptionId=7d27381288e, topicName=变性)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f69f6545041, createdName=huangdf, createdTime=Sat Aug 10 06:27:00 CST 2019, time=2019-08-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1466315, encodeId=bab814663150d, content=<a href='/topic/show?id=765c8925904' target=_blank style='color:#2F92EE;'>#血液学#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89259, encryptionId=765c8925904, topicName=血液学)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=67c86798320, createdName=hxq78318, createdTime=Sat Aug 10 06:27:00 CST 2019, time=2019-08-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1546905, encodeId=4368154690575, content=<a href='/topic/show?id=ed723e350e0' target=_blank style='color:#2F92EE;'>#参考区间#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37350, encryptionId=ed723e350e0, topicName=参考区间)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=910c13959987, createdName=12498dabm81暂无昵称, createdTime=Sat Aug 10 06:27:00 CST 2019, time=2019-08-10, status=1, ipAttribution=)]
    2019-08-10 12498dabm81暂无昵称

    #参考区间#

    0