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AJCN：富含硝酸盐的蔬菜不会降低血压轻度升高的患者的血压

2018-06-17 MedSci MedSci原创

Nitrate-richvegetablesRCTBloodpressure
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最近有研究证据表明，增加摄入富含硝酸盐的蔬菜可能是降低血压的有效方法。本项研究就此进行了前瞻性的研究。

背景
最近有研究证据表明，增加摄入富含硝酸盐的蔬菜可能是降低血压的有效方法。本项研究就此进行了前瞻性的研究。

方法
本项研究将30名患有高血压前期或未经治疗的1级高血压的受试者纳入随机对照交叉试验，治疗周期为4周，以及4周的清除期。参与者按随机顺序完成3次处理：1）增加富含硝酸盐的蔬菜（高硝酸盐（HN））的摄入量（200g / d）； 150mg硝酸盐/ d]，2）增加摄入量（200g / d）贫硝蔬菜[低硝酸盐（LN）； 22毫克硝酸盐/天]和3）不增加蔬菜（对照；6mg硝酸盐/ d）。通过使用食物日记和测量血浆硝酸盐和类胡萝卜素来评估依从性。使用血浆，唾液和尿硝酸盐和亚硝酸盐浓度评估硝酸盐代谢。主要终点是使用24小时门诊，家庭和诊所测量评估的血压。次要结局包括动脉僵硬度的测量。

结果
与LN和对照组两组相比，HN处理的血浆硝酸盐和亚硝酸盐浓度增加（P  <0.001）。与对照组相比，HN和LN处理组血浆类胡萝卜素含量增加（P <0.01）。HN治疗并未降低收缩压[24小时动态-HN：127.4±1.1mmHg； LN：128.6±1.1mm Hg； 对照：126.2±1.1mmHg（P = 0.20）； 家庭血压测量HN：127.4±0.7毫米汞柱； LN：128.7±0.7mmHg； 对照：128.3±0.7mmHg（P  = 0.36）； 临床血压测量HN：128.4±1.3 mm Hg； LN：130.3±1.3mmHg；同样，动脉硬度测量治疗之间没有观察到差异（P > 0.05）。

结论
增加摄入富含硝酸盐的蔬菜并不会降低高血压前期或未经治疗的1级高血压患者的血压。

原始出处

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    2018-10-21 paperyu

    #硝酸盐#

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    2018-06-25 tjdsyyzg

    ***

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    2018-06-25 tjdsyyzg

    ***

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createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4Nd44v3xHnnictn9UpctwtH62EPQ59TMdI9lnqHMgQ16nH7GmGCfpzicsHgjibYVk6vwSpXrC86gMibRkoaIzf5HwSz7/0, createdBy=78cc1691107, createdName=龙胆草, createdTime=Sun Jun 17 15:30:19 CST 2018, time=2018-06-17, status=1, ipAttribution=)]
    2018-06-22 zwjnj2

    好好学习天天学习认真学习

    0

  5. 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createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4Nd44v3xHnnictn9UpctwtH62EPQ59TMdI9lnqHMgQ16nH7GmGCfpzicsHgjibYVk6vwSpXrC86gMibRkoaIzf5HwSz7/0, createdBy=78cc1691107, createdName=龙胆草, createdTime=Sun Jun 17 15:30:19 CST 2018, time=2018-06-17, status=1, ipAttribution=)]
    2018-06-19 chentianping

    #低血压#

    0

  6. 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createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4Nd44v3xHnnictn9UpctwtH62EPQ59TMdI9lnqHMgQ16nH7GmGCfpzicsHgjibYVk6vwSpXrC86gMibRkoaIzf5HwSz7/0, createdBy=78cc1691107, createdName=龙胆草, createdTime=Sun Jun 17 15:30:19 CST 2018, time=2018-06-17, status=1, ipAttribution=)]
    2018-06-17 changjiu

    学习一下谢谢

    0

  7. 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createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzcjoLTEEgkSSQ8pVIiaf4a4INaoMLBV16QEk3dvvBRpicwIwmDGv0jePErJ4aE9ibVBDPtkialQLT9Bs/0, createdBy=04811949400, createdName=邓启付, createdTime=Sun Jun 17 16:18:42 CST 2018, time=2018-06-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=324962, encodeId=5d8132496289, content=学习了.谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7c592194322, createdName=1209e435m98(暂无昵称), createdTime=Sun Jun 17 15:35:14 CST 2018, time=2018-06-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=324956, encodeId=61003249568f, content=学习谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4Nd44v3xHnnictn9UpctwtH62EPQ59TMdI9lnqHMgQ16nH7GmGCfpzicsHgjibYVk6vwSpXrC86gMibRkoaIzf5HwSz7/0, createdBy=78cc1691107, createdName=龙胆草, createdTime=Sun Jun 17 15:30:19 CST 2018, time=2018-06-17, status=1, ipAttribution=)]
    2018-06-17 中医痴

    不错的.学习了.谢谢分享.

    0

  8. [GetPortalCommentsPageByObjectIdResponse(id=1756255, encodeId=c7741e56255e6, content=<a href='/topic/show?id=0249e354370' target=_blank style='color:#2F92EE;'>#硝酸盐#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73543, encryptionId=0249e354370, topicName=硝酸盐)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=29e537091297, createdName=paperyu, createdTime=Sun Oct 21 14:54:00 CST 2018, time=2018-10-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=326918, encodeId=b00b32691807, content=***, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7ad162150, createdName=tjdsyyzg, createdTime=Mon Jun 25 16:41:12 CST 2018, time=2018-06-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=326916, encodeId=20fb3269165e, content=***, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7ad162150, createdName=tjdsyyzg, createdTime=Mon Jun 25 16:37:06 CST 2018, time=2018-06-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=326165, encodeId=110032616586, content=好好学习天天学习认真学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM6DGOvNrRdcib3UmzMgpEQpl0ENSJScphsFtdgfibXX1g1IuEYGCjP23UqCd52TxTpSZibtPiclyusaHicnNXd78alaia19Qy1nAFo18/0, createdBy=50381491660, createdName=zwjnj2, createdTime=Fri Jun 22 20:39:01 CST 2018, time=2018-06-22, status=1, ipAttribution=), 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createdName=changjiu, createdTime=Sun Jun 17 22:51:50 CST 2018, time=2018-06-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=324994, encodeId=c336324994fc, content=不错的.学习了.谢谢分享., beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NdqKgfW3nMpOkC3jXxiaW2po0PtglY5ZuVjERqKADW4HyMI8bcZXWlKgH7tEP9ULBoBzuQMibia4pr1s9rQPqLvqQJ/0, createdBy=e8c02060444, createdName=中医痴, createdTime=Sun Jun 17 19:19:17 CST 2018, time=2018-06-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=324968, encodeId=540f3249688a, content=为什么之前研究和新近研究截然不同., beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzcjoLTEEgkSSQ8pVIiaf4a4INaoMLBV16QEk3dvvBRpicwIwmDGv0jePErJ4aE9ibVBDPtkialQLT9Bs/0, createdBy=04811949400, createdName=邓启付, createdTime=Sun Jun 17 16:18:42 CST 2018, time=2018-06-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=324962, encodeId=5d8132496289, content=学习了.谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7c592194322, createdName=1209e435m98(暂无昵称), createdTime=Sun Jun 17 15:35:14 CST 2018, time=2018-06-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=324956, encodeId=61003249568f, content=学习谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4Nd44v3xHnnictn9UpctwtH62EPQ59TMdI9lnqHMgQ16nH7GmGCfpzicsHgjibYVk6vwSpXrC86gMibRkoaIzf5HwSz7/0, createdBy=78cc1691107, createdName=龙胆草, createdTime=Sun Jun 17 15:30:19 CST 2018, time=2018-06-17, status=1, ipAttribution=)]
    2018-06-17 邓启付

    为什么之前研究和新近研究截然不同.

    0

  9. [GetPortalCommentsPageByObjectIdResponse(id=1756255, encodeId=c7741e56255e6, content=<a href='/topic/show?id=0249e354370' target=_blank style='color:#2F92EE;'>#硝酸盐#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73543, encryptionId=0249e354370, topicName=硝酸盐)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=29e537091297, createdName=paperyu, createdTime=Sun Oct 21 14:54:00 CST 2018, time=2018-10-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=326918, encodeId=b00b32691807, content=***, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7ad162150, createdName=tjdsyyzg, createdTime=Mon Jun 25 16:41:12 CST 2018, time=2018-06-25, status=1, ipAttribution=), 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createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzcjoLTEEgkSSQ8pVIiaf4a4INaoMLBV16QEk3dvvBRpicwIwmDGv0jePErJ4aE9ibVBDPtkialQLT9Bs/0, createdBy=04811949400, createdName=邓启付, createdTime=Sun Jun 17 16:18:42 CST 2018, time=2018-06-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=324962, encodeId=5d8132496289, content=学习了.谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7c592194322, createdName=1209e435m98(暂无昵称), createdTime=Sun Jun 17 15:35:14 CST 2018, time=2018-06-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=324956, encodeId=61003249568f, content=学习谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4Nd44v3xHnnictn9UpctwtH62EPQ59TMdI9lnqHMgQ16nH7GmGCfpzicsHgjibYVk6vwSpXrC86gMibRkoaIzf5HwSz7/0, createdBy=78cc1691107, createdName=龙胆草, createdTime=Sun Jun 17 15:30:19 CST 2018, time=2018-06-17, status=1, ipAttribution=)]
    2018-06-17 1209e435m98(暂无昵称)

    学习了.谢谢分享

    0

  10. [GetPortalCommentsPageByObjectIdResponse(id=1756255, encodeId=c7741e56255e6, content=<a href='/topic/show?id=0249e354370' target=_blank style='color:#2F92EE;'>#硝酸盐#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73543, encryptionId=0249e354370, topicName=硝酸盐)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=29e537091297, createdName=paperyu, createdTime=Sun Oct 21 14:54:00 CST 2018, time=2018-10-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=326918, encodeId=b00b32691807, content=***, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7ad162150, createdName=tjdsyyzg, createdTime=Mon Jun 25 16:41:12 CST 2018, time=2018-06-25, status=1, ipAttribution=), 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createdName=changjiu, createdTime=Sun Jun 17 22:51:50 CST 2018, time=2018-06-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=324994, encodeId=c336324994fc, content=不错的.学习了.谢谢分享., beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NdqKgfW3nMpOkC3jXxiaW2po0PtglY5ZuVjERqKADW4HyMI8bcZXWlKgH7tEP9ULBoBzuQMibia4pr1s9rQPqLvqQJ/0, createdBy=e8c02060444, createdName=中医痴, createdTime=Sun Jun 17 19:19:17 CST 2018, time=2018-06-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=324968, encodeId=540f3249688a, content=为什么之前研究和新近研究截然不同., beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzcjoLTEEgkSSQ8pVIiaf4a4INaoMLBV16QEk3dvvBRpicwIwmDGv0jePErJ4aE9ibVBDPtkialQLT9Bs/0, createdBy=04811949400, createdName=邓启付, createdTime=Sun Jun 17 16:18:42 CST 2018, time=2018-06-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=324962, encodeId=5d8132496289, content=学习了.谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7c592194322, createdName=1209e435m98(暂无昵称), createdTime=Sun Jun 17 15:35:14 CST 2018, time=2018-06-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=324956, encodeId=61003249568f, content=学习谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4Nd44v3xHnnictn9UpctwtH62EPQ59TMdI9lnqHMgQ16nH7GmGCfpzicsHgjibYVk6vwSpXrC86gMibRkoaIzf5HwSz7/0, createdBy=78cc1691107, createdName=龙胆草, createdTime=Sun Jun 17 15:30:19 CST 2018, time=2018-06-17, status=1, ipAttribution=)]
    2018-06-17 龙胆草

    学习谢谢分享

    0

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