Diabetes Obes Metab:糖尿病患者死亡率的有利变化!

2017-06-23 xing.T MedSci原创

由此可见,相比于1999年至2010年期间,2005年至2010年期间糖尿病患者总的、心血管和心脏死亡的结局有了大大的改善。

糖尿病相关并发症在过去20年中有所下降。近日,代谢内分泌疾病领域权威杂志Diabetes Obesity & Metabolism上发表了一篇研究文章,研究人员旨在评估在1999年至2010年期间糖尿病患者的死亡率是否随着时间推移有所改善。

研究人员使用国家健康和营养调查问卷中1999年-2004年和2005年-2010年的数据进行了前瞻性队列研究。初步分析中,研究人员使用Cox比例风险模型比较了糖尿病患者与无糖尿病参与者未经调整的、年龄调整后以及多变量调整后死亡结局(总的、心血管、心脏和癌症死亡)的风险比(HR)。

对于每一个死亡结局,在2005年-2010年期间糖尿病患者的HR(95%可信区间)要低于1999年–2004年期间的HR(全因死亡为2.76 [1.87-4.08] vs. 4.23[2.57-6.98];心血管死亡为2.70[1.20-6.04] vs. 8.82[3.28-23.70];心源性死亡为2.45[0.98-6.09] vs. 15.55[7.01-34.50];癌症死亡为2.33[0.87-6.23] vs. [1.20-7.65])。与1999年-2004年期间相比,在2005年-2010年期间的死亡率在心血管死亡(-54%)和心脏死亡(-64.8%)的跌幅更大。在年龄调整和多变量调整模型中,2005年至2004年期间在有和无糖尿病的参与者中总的、心血管、心脏死亡的累积事件发生率没有显著差异,在1999年至2010年期间的糖尿病患者中没有差异。在2005年至2010年期间,死亡的主要原因是恶性肿瘤。

由此可见,相比于1999年至2010年期间,2005年至2010年期间糖尿病患者总的、心血管和心脏死亡的结局有了大大的改善。

原始出处:

Tetsuro Tsujimoto,et al. Favourable Changes in Mortality in People with Diabetes – U.S. NHANES 1999–2010. Diabetes Obesity & Metabolism.2017. http://onlinelibrary.wiley.com/doi/10.1111/dom.13039/full

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    2017-10-03 柳叶一刀
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    2017-09-08 一闲
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  5. 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  6. 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  7. 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objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c0a61971598, createdName=往日如昨, createdTime=Sat Jun 24 11:29:39 CST 2017, time=2017-06-24, status=1, ipAttribution=)]
    2017-07-08 虈亣靌

    不错的文章值得学习

    0

  8. 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channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5917, encryptionId=c097591ed5, topicName=Diabetes)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0045169, createdName=木头人513, createdTime=Wed Nov 08 21:31:00 CST 2017, time=2017-11-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=220033, encodeId=3ba02200333b, content=不错的文章值得学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zMoyicyo6ia9f4IuLQAwZoxD6Hx4ibd5CMcOCYhStY6oDibbKK6O2X8iaicldO5ib8j1iapOIobIKCGiczU2A/0, createdBy=56251941490, createdName=虈亣靌, createdTime=Sat Jul 08 19:19:09 CST 2017, time=2017-07-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1474220, encodeId=799e14e42201d, content=<a 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  9. [GetPortalCommentsPageByObjectIdResponse(id=1983519, encodeId=ad431983519b9, content=<a href='/topic/show?id=628553048e3' target=_blank style='color:#2F92EE;'>#患者死亡#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=53048, encryptionId=628553048e3, topicName=患者死亡)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=12de429, createdName=sunylz, createdTime=Sat Mar 31 00:31:00 CST 2018, time=2018-03-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1887653, encodeId=7875188e65381, content=<a href='/topic/show?id=d56611584ec' target=_blank style='color:#2F92EE;'>#Meta#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11584, encryptionId=d56611584ec, topicName=Meta)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=778d36, 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channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5917, encryptionId=c097591ed5, topicName=Diabetes)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0045169, createdName=木头人513, createdTime=Wed Nov 08 21:31:00 CST 2017, time=2017-11-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=220033, encodeId=3ba02200333b, content=不错的文章值得学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zMoyicyo6ia9f4IuLQAwZoxD6Hx4ibd5CMcOCYhStY6oDibbKK6O2X8iaicldO5ib8j1iapOIobIKCGiczU2A/0, createdBy=56251941490, createdName=虈亣靌, createdTime=Sat Jul 08 19:19:09 CST 2017, time=2017-07-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1474220, encodeId=799e14e42201d, content=<a href='/topic/show?id=935fe6718e3' target=_blank style='color:#2F92EE;'>#糖尿病患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76718, encryptionId=935fe6718e3, topicName=糖尿病患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a38f7243741, createdName=xue8604, createdTime=Sun Jun 25 06:31:00 CST 2017, time=2017-06-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=214790, encodeId=d6f2214e90db, content=继续学习中谢谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c0a61971598, createdName=往日如昨, createdTime=Sat Jun 24 11:29:43 CST 2017, time=2017-06-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=214789, encodeId=ab26214e8936, content=学习了谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c0a61971598, createdName=往日如昨, createdTime=Sat Jun 24 11:29:39 CST 2017, time=2017-06-24, status=1, ipAttribution=)]
    2017-06-24 往日如昨

    继续学习中谢谢

    0

  10. 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    2017-06-24 往日如昨

    学习了谢谢分享

    0

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