Diabetic Med：1型糖尿病患者的无症状性低血糖：发病率和危险因素

2019-03-26 不详网络

<span style="font-size:9.0pt;font-family:宋体;mso-ascii-theme-font:major-fareast; mso-fareast-theme-font:major-fareast;mso-hansi-theme-font:major-fareast; color:black;mso-bidi-font-weight:bold">近日，国际杂

近日，国际杂志《Diabetic Med》上在线发表一项关于1型糖尿病患者的无症状性低血糖：发病率和危险因素的研究。

目前尚无研究充分描述无症状低血糖的流行病学。研究人员调查了1型糖尿病患者无症状性低血糖的发病率和危险因素。

一组153名患有1型糖尿病的人参加了6天的盲法连续血糖监测（CGM）和记录低血糖症状。在进入研究时，将低血糖意识分类（通过三种不同的方法）并测量HbA 1c和C-肽。低血糖发作定义为间质葡萄糖≤3.9mmol / l（IG 3.9）或≤3.0mmol/l（IG 3.0）≥15min，如果未报告低血糖症状，则认为无症状。

在阈值IG 3.9和IG 3.0，低血糖发作的发生率分别为5.0（7.9）[中位数（IQR）]和1.3（3.4）发作/人 - 周。四分之三的发作无症状。总共有77％和52％的参与者在IG 3.9和IG 3.0 [3.0（6.2）和1.0（2.3）无症状发作/人 - 周]中经历了一次或多次无症状性低血糖发作。在多变量分析中，意识降低与无症状性低血糖，特别是夜间活动呈正相关，与症状性低血糖呈负相关。高胰岛素剂量与无症状和症状性低血糖风险增加相关，而低HbA 1c 和糖尿病病程长，只是症状性低血糖的危险因素。

无症状性低血糖是1型糖尿病中大多数低血糖事件。低血糖意识降低和胰岛素剂量高是无症状低血糖的危险因素，但严重低血糖的其他常规危险因素与无症状发作的风险无关。

原始出处：

M. M. Henriksen ，H. U. Andersen，B. Thorsteinsson，et al. Asymptomatic hypoglycaemia in Type 1 diabetes: incidence and risk factors

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2020-01-18 millore

#1型糖尿病患者#

35 0
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2019-06-14 ms5439512287675881

#BET#

20 0
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2020-01-04 ms9608593228839890

#DIA#

28 0
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2019-08-26 lifestar

#发病率#

25 0
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2019-03-28 xue8604

#糖尿病患者#

32 0
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2019-03-28 12498da4m34(暂无昵称)

#无症状#

30 0
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2019-03-28 ms3994565386320060

#Med#

24 0
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2019-10-12 chenzhuanggui

#Diabetic#

31 0
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2019-03-26 misszhang

谢谢MedSci提供最新的资讯

31 0

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Diabetic Med：1型糖尿病患者的无症状性低血糖：发病率和危险因素

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