JAHA:环境颗粒放射性与血压的关系!

2018-03-15 xing.T MedSci原创

由此可见,这是第一个研究PR对收缩压和舒张压的潜在不良影响的研究。这些都是独立的,类似于那些PM≤2.5µm、黑碳和颗粒数。了解粒子结合放射性核素对血压的影响可能对环境和公共卫生政策有重要影响。

低水平环境辐射暴露对心血管的影响知之甚少。虽然颗粒物(PM)已被证实与心血管疾病的发病率和死亡率以及血压升高有关,但其毒性促进的属性仍然不确定。近日,心血管疾病领域权威杂志JAHA上发表了一篇研究文章,研究人员评估了血压是否随着环境PM放射性成分的高暴露而增加,这里称为颗粒放射性(PR)。

研究人员对852名男性进行了重复测量分析,并用混合效应回归模型研究了PR暴露与血压之间的关系。作为PR的替代品,研究人员使用了由美国环境保护署辐射监测网测量的总β活性。

研究人员发现较高的PR暴露与舒张压和收缩压的增加有关,从1到28天的暴露。28天PR暴露增加一个间距范围导致舒张压增加2.95mmHg(95%可信区间为2.25-3.66;P<0.001)收缩压增加3.94mmHg(95%可信区间2.62-5.27;P<0.001)。对于包括PR和PM≤2.5µm的模型,PR与血压之间的相关性保持稳定和显著。对于包括PR和炭黑或PR和粒子数的模型,,PR与血压之间的相关性减少,但他们仍然显著。

由此可见,这是第一个研究PR对收缩压和舒张压的潜在不良影响的研究。这些都是独立的,类似于那些PM≤2.5µm、黑碳和颗粒数。了解粒子结合放射性核素对血压的影响可能对环境和公共卫生政策有重要影响。

原始出处:

Marguerite M. Nyhan,et al. Associations Between Ambient Particle Radioactivity and Blood Pressure: The NAS (Normative Aging Study).JAHA.2018.https://doi.org/10.1161/JAHA.117.008245

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    2018-03-22 大爰

    学习了谢谢分享!!

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=298578, encodeId=8ea92985e86e, content=学习了谢谢分享!!, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200816/e4675a86ea694f12b82202b320dc2654/12f6b900498349e994ce8f516a584d6a.jpg, createdBy=09431951290, createdName=大爰, createdTime=Thu Mar 22 08:24:20 CST 2018, time=2018-03-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=297318, encodeId=fcdc29e31810, content=学习了谢谢分享!!, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200816/e4675a86ea694f12b82202b320dc2654/12f6b900498349e994ce8f516a584d6a.jpg, createdBy=09431951290, createdName=大爰, createdTime=Sun Mar 18 07:49:50 CST 2018, time=2018-03-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1267771, encodeId=4f8a126e771ba, content=<a href='/topic/show?id=922f21183d' target=_blank style='color:#2F92EE;'>#AHA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2118, encryptionId=922f21183d, topicName=AHA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bf3d82, createdName=zhaohui6731, createdTime=Sat Mar 17 13:39:00 CST 2018, time=2018-03-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=296612, encodeId=54322966123a, content=学习了很有用, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib3IzoRn621JdKCFUI4XvNELcibocrAVU6aUzEVDSaf3rYH08PUYUiagGqxAEhj8g9WqqNvD1CupIpCrmnR2OrqHZh/0, createdBy=7f181365728, createdName=飛歌, createdTime=Fri Mar 16 03:00:24 CST 2018, time=2018-03-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=296596, encodeId=2363296596fa, content=学习学习学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzR8ylhYfiaoAUx2BsaYHVia1IKhG3Cg8CT84rBrn6iaVRkyAibJxBcLEXabOQ5p19vWgDe34ib5ErxNgx/0, createdBy=8a701629084, createdName=jihuaijun1112, createdTime=Fri Mar 16 00:21:51 CST 2018, time=2018-03-16, status=1, ipAttribution=)]
    2018-03-18 大爰

    学习了谢谢分享!!

    0

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    2018-03-17 zhaohui6731
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    2018-03-16 飛歌

    学习了很有用

    0

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    2018-03-16 jihuaijun1112

    学习学习学习

    0