JACC:过高的肺动脉高压诊断标准与死亡率增高相关

2019-05-29 不详 MedSci原创

越来越多的证据表明现有的肺动脉高压(PHT)诊断标准低估了PHT的预后影响。本研究的目的旨在一个澳大利亚人群队列中评估升高的PHT对预后的影响。本研究对157842名研究对象进行了右室收缩压(eRVSP)的检测,并随访其远期预后。该队列包含74405名男性和83437名女性,平均年龄为65.6±17.7岁,最终,根据eRVSP,有17955名(11.4%)、7016名(4.4%)和4515名(2.

越来越多的证据表明现有的肺动脉高压(PHT)诊断标准低估了PHT的预后影响。本研究的目的旨在一个澳大利亚人群队列中评估升高的PHT对预后的影响。

本研究对157842名研究对象进行了右室收缩压(eRVSP)的检测,并随访其远期预后。该队列包含74405名男性和83437名女性,平均年龄为65.6±17.7岁,最终,根据eRVSP,有17955名(11.4%)、7016名(4.4%)和4515名(2.9%)对象有轻度(40-49 mm Hg)、中度(50-59 mm Hg)和重度(≥60 mm Hg)PHT。经过平均4.2年时间的随访,这些PHT的患者死亡率更高(对于严重的PHT来说,HR:9.73; 95% Cl: 8.60-11.0; p < 0.001)。经年龄、性别和心脏病史等因素调整分析后,eRVSP高的死亡风险依旧更高。因此,右室收缩压在30mmHg附近时,患者的死亡率有明显的增高。

研究结果显示,肺动脉高压的右室收缩压诊断标准可以降至30mmHg,新的标准对患者的预后有更高的警示作用。

原始出处:

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    2019-07-10 hbwxf
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    2019-05-31 爆笑小医
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    2019-05-31 liuxiaona
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    2019-05-31 liuxiaona
  7. [GetPortalCommentsPageByObjectIdResponse(id=1925283, encodeId=5df3192528323, content=<a href='/topic/show?id=26d633354c9' target=_blank style='color:#2F92EE;'>#动脉高压#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=33354, encryptionId=26d633354c9, topicName=动脉高压)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=44a360, createdName=jklm09, createdTime=Wed Jan 08 20:08:00 CST 2020, time=2020-01-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1854404, encodeId=19fe185440470, content=<a href='/topic/show?id=48351020537' target=_blank style='color:#2F92EE;'>#JACC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10205, encryptionId=48351020537, topicName=JACC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=55ce62, createdName=hbwxf, createdTime=Wed Jul 10 17:08:00 CST 2019, time=2019-07-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1326225, encodeId=d6f813262259f, content=<a href='/topic/show?id=96c71804b7' target=_blank style='color:#2F92EE;'>#ACC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1804, encryptionId=96c71804b7, topicName=ACC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=395f25, createdName=爆笑小医, createdTime=Fri May 31 01:08:00 CST 2019, time=2019-05-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1385027, encodeId=b701138502e24, content=<a href='/topic/show?id=354691625f1' target=_blank style='color:#2F92EE;'>#诊断标准#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=91625, encryptionId=354691625f1, topicName=诊断标准)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3516494, createdName=spoonycyy, createdTime=Fri May 31 01:08:00 CST 2019, time=2019-05-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1561624, encodeId=9eab1561624ec, content=<a href='/topic/show?id=118142341b1' target=_blank style='color:#2F92EE;'>#增高#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=42341, encryptionId=118142341b1, topicName=增高)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=af9415191444, createdName=liuxiaona, createdTime=Fri May 31 01:08:00 CST 2019, time=2019-05-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1567633, encodeId=2f68156e633a6, content=<a href='/topic/show?id=118142341b1' target=_blank style='color:#2F92EE;'>#增高#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=42341, encryptionId=118142341b1, topicName=增高)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=af9415191444, createdName=liuxiaona, createdTime=Fri May 31 01:08:00 CST 2019, time=2019-05-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1050846, encodeId=d521105084621, content=肺动脉高压表面是罕见病,事实上临床上并不少见,治疗药物虽然有一些,但是整体仍然不理解,可能未来需要采用综合治疗措施。, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=明天jing, createdTime=Wed May 29 13:08:00 CST 2019, time=2019-05-29, status=1, ipAttribution=)]
    2019-05-29 明天jing

    肺动脉高压表面是罕见病,事实上临床上并不少见,治疗药物虽然有一些,但是整体仍然不理解,可能未来需要采用综合治疗措施。

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