Ann Rheum Dis:被动吸烟与患类风湿性关节炎的风险

2018-05-04 xiangting MedSci原创

没有观察到被动吸烟与RA风险之间存在关联,这种现象可以由阈值来解释,低于该阈值时吸烟暴露与RA之间不存在关联。

吸烟与患类风湿性关节炎(RA)的风险升高相关。这项研究的目的是评估被动吸烟对抗环瓜氨酸肽抗体(ACPA)阳性和ACPA阴性RA风险的影响。

这是一项在瑞典进行的基于人群的病例对照研究,使用偶发性RA病例,研究人群限于不吸烟者(589例,1764例对照)。将暴露于被动吸烟的不吸烟者RA发病率与无暴露的不吸烟者进行比较,使用logistic回归计算OR和 95%CI。

未观察到被动吸烟与RA风险之间存在关联(ACPA阳性RA: OR 1.0,95%CI 0.8至1.2;ACPA阴性RA:OR 0.9,95%CI 0.7至1.2)。也未观察到被动吸烟持续时间和RA风险之间的关联趋势。

没有观察到被动吸烟与RA风险之间存在关联,这种现象可以由阈值来解释,低于该阈值时吸烟暴露与RA之间不存在关联。

原始出处:

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    2018-05-06 lmm397
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    2018-05-04 131****1460

    学习了受益匪浅

    0

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    2018-05-04 1ddf0692m34(暂无匿称)

    学习了.谢谢分享

    0

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