Stem cells:羊水干细胞的临床应用潜能

2017-07-03 qinqiyun MedSci原创

羊水,因为其广泛的潜力,被称为是尚未开发的干细胞资源,其具有免疫调节能力,并且没有胚胎干细胞所受的伦理和法律限制。

羊水,因为其广泛的潜力,被称为是尚未开发的干细胞资源,其具有免疫调节能力,并且没有胚胎干细胞所受的伦理和法律限制。羊水干细胞,容易分离和扩增。

已发现从羊水中分离出来的CD117(c-Kit)阳性细胞可以分化成三个胚层的不同细胞系,而且未形成肿瘤,这使其成为再生医学应用的理想候选者。

此外,其定植于受损器官、调节免疫和修复宿主组织应答的能力,提示这类细胞的移植或许可以有效治疗多种退行性和感染性疾病。

尽管在羊水干细胞的起源、多相性表型和发展潜力方面还有很多重要问题,但迄今为止的证据表明羊水干细胞可用于治疗退行性变这一领域的疾病。

原始出处:

Stavros P.Loukogeorgakis,Paolo De Coppi.Concise Review: Amniotic Fluid Stem Cells: The Known, the Unknown, and Potential Regenerative Medicine Applications.25 June 2017.Stem Cells. doi:10.1002/stem.2553

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    2017-12-22 heli0118
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    2017-09-25 维他命
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    2018-01-25 陈吴1243
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