Hepatology:儿童早期维生素E的摄入竟然还有这种好处!

2017-11-12 MedSci MedSci原创

目前,关于儿童早期维生素E(α-生育酚)的摄入量与儿童时期丙氨酸转氨酶(ALT)水平相关的程度尚不清楚。近期,一项发表在杂志Hepatology上的研究旨在评估儿童早期较高的α-生育酚摄入量是否与儿童中期ALT水平升高的几率相关,并考察了儿童体重指数(BMI)如何影响这些关系。研究者们在Viva项目中研究了528名儿童。使用经过验证的食物频率调查问卷调查了儿童的膳食摄入量(中位数为3.1岁)。在儿

目前,关于儿童早期维生素E(α-生育酚)的摄入量与儿童时期丙氨酸转氨酶(ALT)水平相关的程度尚不清楚。

近期,一项发表在杂志Hepatology上的研究旨在评估儿童早期较高的α-生育酚摄入量是否与儿童中期ALT水平升高的几率相关,并考察了儿童体重指数(BMI)如何影响这些关系。

研究者们在Viva项目中研究了528名儿童。使用经过验证的食物频率调查问卷调查了儿童的膳食摄入量(中位数为3.1岁)。在儿童中期(中位数为7.6岁),研究者们收集了儿童的血液和人体测量数据。

此项研究的主要结果是性别特异性儿童中期ALT水平的升高(女性≥22.1单位/升,男性≥25.8单位/升)。在多变量逻辑回归模型中,对儿童中期的年龄、性别、种族、饮食和年龄以及性别特异性BMIz调整后的α-生育酚摄入量与ALT水平的关系。

在这项研究的儿童中,48%是女性,63%是非西班牙裔白人,19%是非西班牙裔黑人,4%是西班牙裔/拉丁裔。儿童早期平均α-生育酚摄入量为3.7±1.0mg/天(范围1.4-9.2)。在儿童中期,平均BMIz为0.41±1.0单位并且ALT水平升高22%。

在多变量校正逻辑回归模型中,儿童早期维生素E摄入较高者的ALT中位数升高的比率较低[校正比值比(AOR)0.62(95%CI:0.39-0.99)]。在考虑到儿童早期饮食后[0.62(0.36,1.08)],研究结果仍然存在,并且在额外考虑儿童中期BMIz 后[0.56(0.32,0.99)],此种相关性更强。

此项研究结果表明:儿童早期摄入较高的α-生育酚与儿童期ALT水平升高的较低几率相关。

原始出处:
Woo Baidal JA, Cheng ER, et al. Association of Vitamin E Intake at Early Childhood with Alanine Aminotransferase Levels at Mid-Childhood. Hepatology. 2017 Nov 9. doi: 10.1002/hep.29629.

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    2017-11-26 jyzxjiangqin

    儿童早期维生素E的摄入.

    0

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    2017-11-21 虈亣靌

    谢谢分享学习了

    0

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    2017-11-14 虈亣靌

    好好看下.内容丰富

    0

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    2017-11-14 1209e435m98(暂无昵称)

    学习了.谢谢分享.

    0

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    2017-11-14 gwc384
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    2017-11-12 changjiu

    学习一下谢谢

    0

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    2017-11-12 131****1460

    学习了受益匪浅

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