Circulation:有心脑血管病的老年人非心脏手术后心肌损伤风险高

2017-12-06 佚名 中国循环杂志

一项发表于Circulation的研究显示,在≥65岁或有冠心病、外周动脉疾病或卒中的患者中,7人中有1人在非心脏手术围手术期发生心肌损伤。

一项发表于Circulation的研究显示,在≥65岁或有冠心病、外周动脉疾病或卒中的患者中,7人中有1人在非心脏手术围手术期发生心肌损伤。

有心肌损伤者在术后30天死亡风险将升高5倍,高死亡风险将持续到术后1年。


图1 伴或不伴围术期心肌损伤者术后30天和1年的累积全因死亡率

研究者还发现,这种围术期心肌损伤较为隐蔽,仅6%的发生者有典型胸痛。

“由于大多数情况下无心脏病症状,很容易遗漏。”研究者指出。具体原因尚不清楚。

研究者指出,认识到这一问题,有助于改善非心脏手术患者的预后,不过目前尚缺乏明确的建议。

研究共纳入2018例心脏病或心脏病高危患者,中位年龄为74岁;受试者共行2546次非心脏手术,包括前列腺或膝关节等低风险手术、髋关节置换或胆囊切除等中等风险手术,和外周动脉搭桥或肺或肝脏切除等高风险手术。研究者通过检测手术前后血肌钙蛋白水平来筛查心肌损伤。

原始出处:Christian Puelacher, Giovanna Lurati Buse, Daniela Seeberger, et al. Perioperative Myocardial Injury After Noncardiac Surgery: Incidence, Mortality, and Characterization. Circulation. 2017;

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2017, time=2017-12-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=267390, encodeId=913d26e39074, content=谢谢分享谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160914/IMG57D82E721DB581755.jpg, createdBy=4fc81933929, createdName=明天会更好!, createdTime=Thu Dec 07 00:05:28 CST 2017, time=2017-12-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=267283, encodeId=ebb826e28311, content=学习了.获益匪浅!感谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/07/17/0ed05bbc4eb124766d2a39104932ec4e.jpg, createdBy=5afd2091871, createdName=情途末路, createdTime=Wed Dec 06 14:26:54 CST 2017, time=2017-12-06, status=1, ipAttribution=)]
    2017-12-07 明天会更好!

    谢谢分享谢谢分享!

    0

  9. 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2017, time=2017-12-06, status=1, ipAttribution=)]
    2017-12-06 情途末路

    学习了.获益匪浅!感谢分享

    0

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