J Periodontal Res:甘氨酸粉末空气抛光作为慢性牙周炎患者非手术牙周治疗方法的效果

2018-04-01 MedSci MedSci原创

甘氨酸粉末空气抛光(GPAP)是去除龈下菌斑生物膜以进行有效牙周治疗的替代方法。本研究旨在探讨龈下GPAP作为慢性牙周炎患者非手术牙周治疗方法的效果。招募了二十七名不吸烟的受试者。将每个受试者的两个象限随机分配,根据分口设计,在探诊深度≥5mm的部位进行洁治和根面平整(SRP)和GPAP(试验组)或SRP和空气冲洗(对照组)。在基线和治疗后1、3和6个月测量龈沟液的临床参数,包括龈沟液量和白细胞介

甘氨酸粉末空气抛光(GPAP)是去除龈下菌斑生物膜以进行有效牙周治疗的替代方法。本研究旨在探讨龈下GPAP作为慢性牙周炎患者非手术牙周治疗方法的效果。

招募了二十七名不吸烟的受试者。将每个受试者的两个象限随机分配,根据分口设计,在探诊深度≥5mm的部位进行洁治和根面平整(SRP)和GPAP(试验组)或SRP和空气冲洗(对照组)。在基线和治疗后1、3和6个月测量龈沟液的临床参数,包括龈沟液量和白细胞介素-1β和白细胞介素-1ra的浓度。

结果显示,基线时,试验组和对照组之间未发现牙周和龈沟液参数存在明显地统计学差异。总体而言,所有受试者的牙周状况在治疗后得到明显改善。值得注意的是,试验组3个月时龈沟液体积(0.37±0.26μL)较对照组(0.23±0.30μL)明显降低(P <0.05)。 6个月时两组龈沟液中白细胞介素-1β和白细胞介素-1ra水平均明显下降,组间差异无统计学意义。

这些初步结果表明,作为非手术牙周治疗的另一种方法,GPAP可能有利于亚临床炎症的短期改善。需要更大样本量的进一步纵向研究来阐明GPAP治疗控制炎症和维持长期牙周健康的确切益处。

原始出处:


Tsang YC, Corbet EF, Jin LJ. Subgingival glycine powder air-polishing as an additional approach to nonsurgical periodontal therapy in subjects with untreated chronic periodontitis. J Periodontal Res. 2018 Mar 25. doi: 10.1111/jre.12532

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    2018-10-20 feather89
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    2018-06-30 徐岩
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    2018-04-01 清风拂面

    谢谢分享学习

    0

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已知纤溶酶原基因(PLG)中的内含子变体rs4252120与侵袭性牙周炎(AgP)和动脉粥样硬化有关。此次我们研究了跨PLG的染色体区域与慢性牙周炎(CP)和AgP的关联。

J Endod:通过电和冷热刺激测试评估慢性牙周炎对牙髓活力的影响

研究已证实,在牙髓与牙周组织之间存在信号通讯。然而,牙周疾病是否会引起牙髓组织产生临床反应还未可知。这篇研究的目的是通过电和冷热刺激测试评估牙周疾病的严重程度对牙髓活力的影响。

J Periodontol:健康人与慢性牙周炎、心肌梗死患者内皮功能的比较

重度牙周病患者内皮细胞会有损害,内皮功能的破坏有助于动脉粥样硬化斑块的形成,进而可能成为冠状动脉疾病的风险。本研究的目的是通过血管舒张功能(FMD)评估牙周健康和疾病中的内皮功能。