Pain：针灸可有效预防偏头痛复发和加重
2011-10-18 MedSci原创 MedSci原创
记者从日前在京召开的2011年针灸国际研讨会上获悉，首都医科大学附属北京中医医院针灸中心经临床研究证实，传统的中医针灸疗法可有效预防偏头痛的复发和加重。相关研究论文近日发表在国际著名医学期刊《疼痛》上，成为中国大陆首篇发表于该杂志的临床研究论文。该文还被国际知名医学生物学机构 Faculty of 1000 medicine（千名医学家）收录。 据了解，作为临床常见病之一，偏头痛发病率高，且危害
记者从日前在京召开的2011年针灸国际研讨会上获悉，首都医科大学附属北京中医医院针灸中心经临床研究证实，传统的中医针灸疗法可有效预防偏头痛的复发和加重。相关研究论文近日发表在国际著名医学期刊《疼痛》上，成为中国大陆首篇发表于该杂志的临床研究论文。该文还被国际知名医学生物学机构 Faculty of 1000 medicine（千名医学家）收录。
据了解，作为临床常见病之一，偏头痛发病率高，且危害严重。目前，我国18岁~65岁人群的偏头痛患病率高达9.3%，且有逐年升高趋势。针灸治疗头痛在中国已经有数千年的历史。北京中医医院针灸中心自2004年设立头痛专家门诊，开展了基于“金针王乐亭”、国医大师贺普仁等多位著名针灸学家治痛经验的头痛研究。
据该中心主任王麟鹏介绍，该项目采取单盲、双模拟、随机对照的形式，在国内5家医院的针灸科共招募140名无先兆偏头痛患者，随机分为两组，分别为治疗组（针灸加安慰剂）和对照组（假针加氟桂利嗪）。两组患者每周针灸治疗3次，每晚口服药物。结果显示，4周后，治疗组偏头痛的有效缓解率为59%，对照组为40%；治疗组疼痛天数平均下降4.1天，对照组平均下降1.9天。16周后，治疗组有效缓解率为56%，对照组为37%；治疗组疼痛天数平均下降 4.1天，对照组平均下降2天。
研究人员据此认为，针灸可以作为偏头痛的预防复发和加重的方法，其治疗效果也优于此前国外的相关研究。由于其研究方法的新颖和重要性，该论文还被国际知名医学生物学机构“千名科学家”收录。（生物谷 Bioon.com）
Efficacy of acupuncture for migraine prophylaxis: A single-blinded, double-dummy, randomized controlled trial
Lin-Peng Wang,Xiao-Zhe Zhang,Jia Guo,Hui-Lin Liu,Yan Zhang,Cun-Zhi Liu,Jing-Hong Yi,Li-Ping Wang,Ji-Ping Zhao,Shan-Shan Li
Summary This multicenter, double-dummy trial suggested that acupuncture was more effective than flunarizine in decreasing days of migraine attacks. Abstract Insufficient clinical trial data were available to prove the efficacy of acupuncture for migraine prophylaxis. A multicenter, double-dummy, single-blinded, randomized controlled clinical trial was conducted at the outpatient departments of acupuncture at 5 hospitals in China to evaluate the effectiveness of acupuncture. A total of 140 patients with migraine without aura were recruited and assigned randomly to 2 different groups: the acupuncture group treated with verum acupuncture plus placebo and the control group treated with sham acupuncture plus flunarizine. Treated by acupuncture 3 times per week and drugs every night, patients from both groups were evaluated at week 0 (baseline), week 4, and week 16. The primary outcome was measured by the proportion of responders (defined as the proportion of patients with a reduction of migraine days by at least 50%). The secondary outcome measures included the number of migraine days, visual analogue scale (VAS, 0 to 10cm) for pain, as well as the physical and mental component summary scores of the 36-item short-form health survey (SF-36). The patients in the acupuncture group had better responder rates and fewer migraine days compared with the control group (P<.05), whereas there were no significant differences between the 2 groups in VAS scores and SF-36 physical and mental component summary scores (P>.05). The results suggested that acupuncture was more effective than flunarizine in decreasing days of migraine attacks, whereas no significantly differences were found between acupuncture and flunarizine in reduction of pain intensity and improvement of the quality of life.
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