J Hypertens:原发性高血压患者抗高血压药物依从性的影响因素分析!

2017-05-27 xing.T MedSci原创

由此可见,几个患者因素被确认作为抗高血压类药物类别和治疗依从性的决定因素;因此,它们可以帮助确定有不依从性风险的患者,因此可以针对它们进行依从性改善干预。

近日,高血压领域权威杂志Journal of Hypertension上发表了一篇研究文章,研究人员旨在探讨高血压患者服用抗高血压药物的整体(治疗依从性)与特定药物类别(药物类别依从性)依从性的相关因素。

该回顾性队列研究纳入了2006年4月至2013年3月期间来自于英国临床实践研究数据链中的原发性高血压患者。参与者从第一类降压药物(药物类别依从性)进入处方之日起,以及从第一次接触抗高血压药物(治疗依从性)之日起开始随访至研究结束、或病人离开数据库或死亡。研究人员记录参与者六类抗高血压药物的使用时间(从各类药物首次进入处方到随访结束的时间)。服用抗高血药物天数复盖比例(PDC)被用来估计随访期间高血压患者抗高血压药物治疗的治疗依从性以及每一类药特定的药物类别依从性。研究人员采用广义线性模型来评估PDC的相关因素。

在176835例患者和371605个处方中,中位数治疗和药物类别PDC分别为93.9和98.3%,分别有20%的患者和38.4%的处方PDC不到80%。较高的治疗和药物类别PDC与年龄增加、使用肾素血管紧张素药物,以及既往的病人和抗高血压药物使用者相关。较高的剥夺、多发性合并症和降压药物的切换与较低的PDC相关。

由此可见,几个患者因素被确认作为抗高血压类药物类别和治疗依从性的决定因素;因此,它们可以帮助确定有不依从性风险的患者,因此可以针对它们进行依从性改善干预。

原始出处:

Kurdi, Amanj I,et al. Exploring factors associated with patients' adherence to antihypertensive drugs among people with primary hypertension in the United Kingdom.Journal of Hypertension. 2017. http://journals.lww.com/jhypertension/Abstract/publishahead/Exploring_factors_associated_with_patients_.97733.aspx

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href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=15, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Tue Mar 27 13:49:00 CST 2018, time=2018-03-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1465539, encodeId=fb1c1465539a2, content=<a href='/topic/show?id=144f5032688' target=_blank style='color:#2F92EE;'>#影响因素#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=50326, encryptionId=144f5032688, topicName=影响因素)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=80a06745918, createdName=chenzhuanggui, createdTime=Mon May 29 13:49:00 CST 2017, time=2017-05-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1545675, encodeId=bd1d15456e505, content=<a href='/topic/show?id=a383558515b' target=_blank style='color:#2F92EE;'>#抗高血压药物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=55851, encryptionId=a383558515b, topicName=抗高血压药物)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e46713811513, createdName=ms9474365431325850, createdTime=Mon May 29 13:49:00 CST 2017, time=2017-05-29, status=1, ipAttribution=)]
    2017-06-06 laoli

    学习了,谢谢分享!

    0

  8. 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href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=15, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Tue Mar 27 13:49:00 CST 2018, time=2018-03-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1465539, encodeId=fb1c1465539a2, content=<a href='/topic/show?id=144f5032688' target=_blank style='color:#2F92EE;'>#影响因素#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=50326, encryptionId=144f5032688, topicName=影响因素)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=80a06745918, createdName=chenzhuanggui, createdTime=Mon May 29 13:49:00 CST 2017, time=2017-05-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1545675, encodeId=bd1d15456e505, content=<a href='/topic/show?id=a383558515b' target=_blank style='color:#2F92EE;'>#抗高血压药物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=55851, encryptionId=a383558515b, topicName=抗高血压药物)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e46713811513, createdName=ms9474365431325850, createdTime=Mon May 29 13:49:00 CST 2017, time=2017-05-29, status=1, ipAttribution=)]
    2018-03-27 feather89
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