JAMA Oncology:长达7年随访表明,遵守ACS营养和运动指南,能使中期肠癌患者术后5年生存率提高9%

2018-04-27 苑腊静,谭硕 奇点网

近期发表在《美国医学会杂志-肿瘤学》(JAMA Oncology)上的一项临床研究结果显示显示:如果严格遵循美国癌症协会制定的营养和运动指南,诊断时处于病情中期的结肠癌患者(III期),术后5年生存率可以从76%提高到85%,死亡风险相对下降了42%!

近期发表在《美国医学会杂志-肿瘤学》(JAMA Oncology)上的一项临床研究结果显示显示:如果严格遵循美国癌症协会制定的营养和运动指南,诊断时处于病情中期的结肠癌患者(III期),术后5年生存率可以从76%提高到85%,死亡风险相对下降了42%!

得了癌症想吃什么就吃什么?别想这种好事……

结直肠癌,本来就是一种与食物关系密切的癌症。众所周知,食物中的膳食纤维能够有效地降低肠癌的发病率,每天吃90克的谷物,能把患肠癌的风险降低17%。

而坚果则有益结直肠癌患者的术后恢复,耶鲁癌症中心的研究人员开展了一项大型临床研究发现,吃坚果对结肠癌患者好处多多!对于每周至少吃2次,每次约28g坚果的Ⅲ期结肠癌患者来说,在6.5年的随访期内,无病生存率提高了42%,总体生存率提高了57%。

不过这些研究,主要针对的是单一食物或营养素对肠癌的影响,患者总不能只吃一种食物过日子吧?好在美国癌症协会(ACS)也为癌症患者们专门量身打造了营养和运动指南。指南虽好,也得在患者严格遵从的状况下才能取得效果。

说什么食物治愈癌症肯定是假的,但说食物能帮得上忙肯定是真的

为了全面评价患者对饮食和运动指南依从性在生存率方面的影响,由加州大学旧金山分校领衔的研究团队对肠癌临床试验CALGB 89803的受试者进行了平均为期7年的随访,这一接受过根治手术和术后化疗的受试者群体,已经成为评价饮食和运动对癌症患者影响的重要数据来源之一,坚果抗癌数据就出自于此。

研究团队以问卷的形式对992名受试者的运动和饮食情况进行调查,然后对比ACS指南进行打分,从0到6分的不同分值反映了患者的依从性,分数越高,依从性越好。在随访期间,有335名受试者癌症复发,299人死亡,其中256人因复发而死。

总体来看,26%的参与者ACS指南依从性评分为0-1分,9%的参与者评分为5至6分。而数据统计的结果表明,依从指南最好(5-6分)的肠癌患者,比依从性低(0-4分)的患者五年生存率提高了9%,死亡风险下降了42%,并且具有更好的无病和无复发生存期。

讲到这儿,估计又是一大波询问具体食谱的问题要向奇点糕袭来了……秉承着勤学好问、造福群众的态度,奇点糕总结了一下ACS指南的精华,感兴趣的朋友们,现在可以拿出你的的小本本准备做笔记了。

当前ACS营养和运动指南主要分为以下几部分:

·达到并保持健康的体重

如果是超重或肥胖,一定要限制摄入高热量的食物和饮料并增加体力活动以促进体重的减轻。专家认为18.5~24.9范围内的BMI是健康的, 25~29.9之间是超重,>30则是肥胖。

·定期参加体力锻炼

确诊癌症后尽量避免不活动,并尽快恢复正常的日常活动。

每周至少锻炼150分钟。

包括每周至少2天的力量训练。

·实现蔬菜,水果和全谷物的膳食模式

限制食用加工肉类和红肉

每天至少2.5杯(1杯=250ml)蔬菜和水果

选择全谷类代替精制谷物

·限制饮酒

建议常饮酒者减少酒量,至少降至男性每天10盎司(约280g)白酒或24盎司(约680g)啤酒,女性每天5盎司(约140g)白酒或12盎司(约340g)啤酒。

每次唠叨肥胖的话题,奇点糕都要说经典的六字经:“管住嘴,迈开腿”。但谁说这一套就不能用到癌症患者身上呢?努力吧~

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    2018-10-03 minlingfeng
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    2018-04-30 神功盖世

    0

  4. 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content=^_^^_^^_^, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/Swp2ehfHpiciczeTntUyQOlIGMzQ705ic67sdMTVMbwTv7KbmlUvxrGvRSvQZjPkz7ib5tEDfIaORgczPtmHDpwojg/0, createdBy=c54b2163125, createdName=wqkm, createdTime=Fri Apr 27 23:56:27 CST 2018, time=2018-04-27, status=1, ipAttribution=)]
    2018-04-30 sunfeifeiyang

    0

  5. 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  6. 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content=^_^^_^^_^, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/Swp2ehfHpiciczeTntUyQOlIGMzQ705ic67sdMTVMbwTv7KbmlUvxrGvRSvQZjPkz7ib5tEDfIaORgczPtmHDpwojg/0, createdBy=c54b2163125, createdName=wqkm, createdTime=Fri Apr 27 23:56:27 CST 2018, time=2018-04-27, status=1, ipAttribution=)]
    2018-04-29 yaanren
  7. 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createdBy=b63894, createdName=minlingfeng, createdTime=Wed Oct 03 00:29:00 CST 2018, time=2018-10-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=310707, encodeId=01ff310e07c3, content=阅, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/fhZdOu27e88Voqh19n8eF8cLplo8L4nicKtH0WnE3KFELXns5XDu8rsiceK2HHDZc2SEStia5VV3Pia2QLMVqlWbHw/0, createdBy=6e012139475, createdName=神功盖世, createdTime=Mon Apr 30 12:28:48 CST 2018, time=2018-04-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=310701, encodeId=d16c310e013c, content=阅, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, 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channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1882, encryptionId=316d1882bc, topicName=ACS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=102a153, createdName=yaanren, createdTime=Sun Apr 29 14:29:00 CST 2018, time=2018-04-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=310336, encodeId=149a3103369a, content=阅, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/09/07/a9772c74ffd6edc03a7f9af07b4747f6.jpg, createdBy=b3722138742, createdName=sunfeifeiyang, createdTime=Sun Apr 29 08:03:54 CST 2018, time=2018-04-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=309994, encodeId=ba713099943b, content=学了, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKcmgibQ4oCrK7Z6f4CvMcs4k7QUGCkhopcGxvxaBfVciadECSIwaRVttllIOEKumpEaRrq5PoOUxow/0, createdBy=e3bb2081203, createdName=哈哈869, createdTime=Sat Apr 28 06:54:45 CST 2018, time=2018-04-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=309910, encodeId=4a8130991086, content=谢谢分享学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM7GibvIBibibnnnvpajk2stlDF5oichYahI6Bia8uxeTBFoPbdoHWebyXf9eal9FNgUF2lNcrwoZicM3BvQ/0, createdBy=a3742066385, createdName=戒馋,懒,贪, createdTime=Sat Apr 28 00:08:30 CST 2018, time=2018-04-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=309903, encodeId=305c309903ae, content=^_^^_^^_^, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/Swp2ehfHpiciczeTntUyQOlIGMzQ705ic67sdMTVMbwTv7KbmlUvxrGvRSvQZjPkz7ib5tEDfIaORgczPtmHDpwojg/0, createdBy=c54b2163125, createdName=wqkm, createdTime=Fri Apr 27 23:56:27 CST 2018, time=2018-04-27, status=1, ipAttribution=)]
    2018-04-29 sunfeifeiyang

    0

  8. 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likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKcmgibQ4oCrK7Z6f4CvMcs4k7QUGCkhopcGxvxaBfVciadECSIwaRVttllIOEKumpEaRrq5PoOUxow/0, createdBy=e3bb2081203, createdName=哈哈869, createdTime=Sat Apr 28 06:54:45 CST 2018, time=2018-04-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=309910, encodeId=4a8130991086, content=谢谢分享学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM7GibvIBibibnnnvpajk2stlDF5oichYahI6Bia8uxeTBFoPbdoHWebyXf9eal9FNgUF2lNcrwoZicM3BvQ/0, createdBy=a3742066385, createdName=戒馋,懒,贪, createdTime=Sat Apr 28 00:08:30 CST 2018, time=2018-04-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=309903, encodeId=305c309903ae, content=^_^^_^^_^, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/Swp2ehfHpiciczeTntUyQOlIGMzQ705ic67sdMTVMbwTv7KbmlUvxrGvRSvQZjPkz7ib5tEDfIaORgczPtmHDpwojg/0, createdBy=c54b2163125, createdName=wqkm, createdTime=Fri Apr 27 23:56:27 CST 2018, time=2018-04-27, status=1, ipAttribution=)]
    2018-04-28 哈哈869

    学了

    0

  9. 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likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKcmgibQ4oCrK7Z6f4CvMcs4k7QUGCkhopcGxvxaBfVciadECSIwaRVttllIOEKumpEaRrq5PoOUxow/0, createdBy=e3bb2081203, createdName=哈哈869, createdTime=Sat Apr 28 06:54:45 CST 2018, time=2018-04-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=309910, encodeId=4a8130991086, content=谢谢分享学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM7GibvIBibibnnnvpajk2stlDF5oichYahI6Bia8uxeTBFoPbdoHWebyXf9eal9FNgUF2lNcrwoZicM3BvQ/0, createdBy=a3742066385, createdName=戒馋,懒,贪, createdTime=Sat Apr 28 00:08:30 CST 2018, time=2018-04-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=309903, encodeId=305c309903ae, content=^_^^_^^_^, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/Swp2ehfHpiciczeTntUyQOlIGMzQ705ic67sdMTVMbwTv7KbmlUvxrGvRSvQZjPkz7ib5tEDfIaORgczPtmHDpwojg/0, createdBy=c54b2163125, createdName=wqkm, createdTime=Fri Apr 27 23:56:27 CST 2018, time=2018-04-27, status=1, ipAttribution=)]
    2018-04-28 戒馋,懒,贪

    谢谢分享学习了

    0

  10. 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    0

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