Eur Radiol:头颈部恶性肿瘤发生沿神经侵犯后,后果令人堪忧!

2017-12-12 shaosai MedSci原创

本研究旨在验证18F-FDG PET中的定量影像学指标是否能够提示头颈部恶性肿瘤(HNM)发生沿神经侵犯(PNS),从而提高患者危险分层的质量,并将结果发表在Eur Radiol上。

本研究旨在验证18F-FDG PET中的定量影像学指标是否能够提示头颈部恶性肿瘤(HNM)发生沿神经侵犯(PNS),从而提高患者危险分层的质量,并将结果发表在Eur Radiol上。

本病例对照研究(1:2)共纳入了81例FDG怀疑的HNM,病例组包括28例诊断为PNS的患者,包括14例鳞癌(SCC)。从PNS患者的18F-FDG PET、CT、 MRI提取数据。对照组包括53例SCC患者。利用Cox比例风险回归模型联合单变量及多变量分析评价其与总生存率的相关性。

结果为,在病例组18F-FDG PET检出 PNS的比例为100%。定量影像学指标与感觉(p>0.20)或运动(p>0.10)症状并无相关性。在SCC的患者(病例组14例,对照组53例),多变量分析显示PNS与死亡具有相关性,风险比例为5.5(95%CI: 1.4:20.9)。单变量分析显示,颅神经SUVmax增加与总生存率较差具有相关性(p=0.001)。

本研究表明能够从18F-FDG PET中提取PNS的影像学标识物。

原始出处:

Dercle L, Hartl D, Rozenblum-Beddok L. et al.Diagnostic and prognostic value of 18F-FDG PET, CT, and MRI in perineural spread of head and neck malignancies.Eur Raidol.DOI: 10.1007/s00330-017-5087-2

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    2018-05-04 1e145228m78(暂无匿称)

    学习了.谢谢作者分享!

    0

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    2018-05-01 1e145228m78(暂无匿称)

    学习了.谢谢作者分享!

    0

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    2017-12-14 wshxjq
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    2017-12-12 131****1460

    学习了受益匪浅

    0

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    2017-12-12 changjiu

    学习一下谢谢

    0

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