J Rheumatol:银屑病关节炎的医师全面评估:多中心GRAPPA研究

2018-06-16 xiangting MedSci原创

通过VAS评估PGA是评价MSK和皮肤病疾病活动性的可靠工具。

对疾病活动性的医师全面评估(PGA)是治疗决策的主要决定因素。这项研究评估了银屑病关节炎(PsA)患者中PGA的可靠性,通过0-100mm视觉模拟量表(VAS),和对肌肉骨骼(PhysMSK)和皮肤病学(PhysSk)表现单独使用VAS量表来衡量。

纳入来自8个国家16个中心的319名连续性PsA患者。在入组时(W0)和1周后(W1)完成PGA、PhysMSK和PhysSk评估表。记录关于肌肉骨骼(MSK)表现和皮肤病学评估的详细临床数据。

W0和W1评分比较没有显著差异(组内相关系数分别为PGA 0.87,PhysMSK 0.86,PhysSk 0.78),证明了仪器的可靠性。与皮肤(B = 0.32)相比,PGA评分依赖于PhysMSK和PhysSk(p<0.0001),其中MSK成分起主要作用(B = 0.69)。PhysMSK与肿胀关节、触痛关节的数目和存在指炎相关(p<0.0001)。PhysSk评分与皮肤银屑病的程度和面部、臀部或臀间或脚部受累相关(p<0.0001)。最后,比较了医师评价和患者自我评估,发现不匹配频繁和散点图:PGA vs.患者全面评估(r=0.36),PhysMSK vs.患者MSK(r=0.39)以及PhysSk vs.患者皮肤(r=0.49)。

通过VAS评估PGA是评价MSK和皮肤病疾病活动性的可靠工具。PGA不同于患者的自我评估。由于MSK和皮肤/指甲疾病活动性可能不同,因此建议同时进行PhysMSK和PhysSk评估。

原始出处:

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    2018-09-21 luoxiaog
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    2018-06-21 jihuaijun1112

    学习学习学习

    0

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    2018-06-18 lmm397
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    2018-06-16 changjiu

    学习一下谢谢

    0

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    2018-06-16 清风拂面

    谢谢分享学习

    0

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    2018-06-16 邓启付

    银屑病关节炎是银屑病比较严重的临床症状.

    0

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    2018-06-16 三生有幸9135

    学习一下谢谢

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    2018-06-16 1e0f8808m18(暂无匿称)

    好文章.学习了.

    0

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