Clin Oral Investig:微生物学分析和有或无辅助全身抗生素的牙周治疗结果

2018-03-01 MedSci MedSci原创

本回顾性研究旨在评估微生物诊断对伴或不伴辅助全身应用抗生素治疗牙周治疗结局的影响。材料和方法:非手术牙周治疗之前(T1)和之后(T2)对患者进行微生物分析。从病人档案中提取病史、诊断、临床数据和微生物分析结果。描述性统计之后,进行logistic回归分析以模拟T2(90%-PD5和50%-PD5)时探针深度(PD)≥5mm的部位数目减少90%和50%。结果:研究共纳入了18名侵袭性牙周炎的患者(A

本回顾性研究旨在评估微生物诊断对伴或不伴辅助全身应用抗生素治疗牙周治疗结局的影响。

材料和方法:
非手术牙周治疗之前(T1)和之后(T2)对患者进行微生物分析。从病人档案中提取病史、诊断临床数据和微生物分析结果。描述性统计之后,进行logistic回归分析以模拟T2(90%-PD5和50%-PD5)时探针深度(PD)≥5mm的部位数目减少90%和50%。

结果:
研究共纳入了18名侵袭性牙周炎的患者(AP,17例辅助性抗生素)和84例慢性牙周炎(CP,31例辅助性抗生素)。T1至90%-PD5的细菌Logistic模型显示不存在明显的统计学差异。使用50%-PD5,在T1时存在所有牙龈卟啉单胞菌,福赛坦氏菌和齿垢密螺旋体,特别是齿垢密螺旋体与对治疗的良好反应有关。在T2时,细菌存在至90%-PD5和50%-PD5的模拟发现与福赛坦氏菌(90%PD5和50%PD5)以及福赛坦氏菌和直肠弯曲菌(50%-PD5 )不存在相关。对T1,抗生素组和T2期口腔卫生进行模拟,结果显示50%-PD5时,辅助抗生素组的比值比(OR)在2.70和52.4之间,口腔卫生在3.27和4.11之间,在T1时可达28.6(牙龈卟啉单胞菌,福赛坦氏菌或齿垢密螺旋体)。

结论:
与牙周病相关的最重要的微生物分析似乎支持临床决定辅助使用全身性抗生素。

原始出处:

Eick S, Nydegger J, et al., Microbiological analysis and the outcomes of periodontal treatment with or without adjunctive systemic antibiotics-a retrospective study. Clin Oral Investig. 2018 Feb 21. doi: 10.1007/s00784-018-2392-3.

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    2019-01-28 小几洁
  4. 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status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1535918, encodeId=bac4153591877, content=<a href='/topic/show?id=ae716469300' target=_blank style='color:#2F92EE;'>#治疗结果#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=64693, encryptionId=ae716469300, topicName=治疗结果)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=fa8e12645559, createdName=jiadan198786, createdTime=Sat Mar 03 05:38:00 CST 2018, time=2018-03-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1617857, encodeId=f4ba161e8576b, content=<a href='/topic/show?id=e88f6930185' target=_blank style='color:#2F92EE;'>#生物学#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=69301, encryptionId=e88f6930185, topicName=生物学)], attachment=null, authenticateStatus=null, 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  5. 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  6. 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  7. 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    2018-03-01 1ddf0692m34(暂无匿称)

    学习了.谢谢分享

    0