BMJ:白肉比红肉有益的证据来啦!

2017-05-10 xing.T MedSci原创

这些结果显示由于与红肉摄入相关的九种不同原因,全因死亡率和死亡风险增加,考虑到,部分与血红素铁和加工肉类中的硝酸盐/亚硝酸盐相关。研究人员还发现摄入白色与减少的风险相关,特别是未经加工的白肉。

近日,顶级杂志BMJ上发表了一篇研究文章,研究人员旨在明确不同类型肉类摄入量和肉类相关混合物与整体和病因特异性死亡率之间的相关性。

该研究为以人群为基础的队列研究,并且基于NIH-AARP饮食与健康研究(在美国六个州和两个大都市地区一般人群的前瞻性队列研究)的基础饮食数据和16年随访(直至2011年12月31日)数据。参与者为536969名50-71岁的AARP成员,暴露因素为根据膳食调查得到的总肉类、加工和未加工的红肉(牛肉、羊肉和猪肉)和白肉(家禽和鱼)、血红素铁以及在肉类加工过程中加入的硝酸盐/亚硝酸盐摄入量。研究人员所用的调整后Cox比例风险回归模型中以最低五分位数热量作为对照。该研究的主要观察指标为随访期间任何原因引起的死亡。

由于与红肉摄入相关的九种不同原因,研究人员观察到全因死亡风险增加(最高五分位数比上最低五分位数的风险比为1.26,95%可信区间为1.23-1.29)。加工和未加工的红肉摄入量均与全因和病因特异性死亡率相关。血红素铁和加工肉类中硝酸盐/亚硝酸盐与全因和病因特异性死亡率风险增加之间存在独立相关性。模型估计死亡率的增加与加工红肉相关,并受硝酸盐的摄入量影响(37.0-72.0%),而受血红素铁的影响程度较小(20.9-24.1 %)。当总的肉类摄入量恒定时,白肉摄入量位于最高五分位数范围的参与者全因死亡率风险相比于最低五分位数范围的参与者减少了25%。几乎所有的死亡原因与白肉摄入量呈负相关性。

这些结果显示由于与红肉摄入相关的九种不同原因,全因死亡率和死亡风险增加,考虑到,部分与血红素铁和加工肉类中的硝酸盐/亚硝酸盐相关。研究人员还发现摄入白色与减少的风险相关,特别是未经加工的白肉。

原始出处:


Arash Etemadi, et al. Mortality from different causes associated with meat, heme iron, nitrates, and nitrites in the NIH-AARP Diet and Health Study: population based cohort study.BMJ 2017; 357. http://www.bmj.com/content/357/bmj.j1957

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    2018-01-31 gaoxiaoe
  2. 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    2017-06-23 1e1263e3m20(暂无匿称)

    有理有力,学习了

    0

  3. 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    2017-06-20 lofter

    学习了,感谢分享

    0

  4. 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status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=197799, encodeId=d24b19e79977, content=认真学习,把间接经验应用到临床实践中去,然后再总结出新思路。给点赞啦……, beContent=null, objectType=article, channel=null, level=null, likeNumber=20, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Sun May 14 06:52:15 CST 2017, time=2017-05-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=197598, encodeId=b40919e5986b, content=学习了,谢谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, 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topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Fri May 12 07:09:10 CST 2017, time=2017-05-12, status=1, ipAttribution=)]
    2017-05-18 I come

    好文章,学习了,谢谢分享

    0

  5. 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topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Fri May 12 07:09:10 CST 2017, time=2017-05-12, status=1, ipAttribution=)]
    2017-05-16 cuiyejia

    学习了,谢谢

    0

  6. 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topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Fri May 12 07:09:10 CST 2017, time=2017-05-12, status=1, ipAttribution=)]
    2017-05-16 ylzr123

    好文,值得点赞!认真学习,应用于实践!谢谢分享给广大同好!

    0

  7. 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createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuOWcPEsEP4FrvDcicue5V6rMkmXmY73KjYP59vQrEdjU89iaN4ZkOhsItlHkmGTjhV3b5S3zOQA4E0/0, createdBy=cc261682151, createdName=卡圣, createdTime=Sat May 13 15:41:05 CST 2017, time=2017-05-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=197390, encodeId=462d19e39055, content=白肉比红肉有益的证据。, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Sat May 13 07:12:46 CST 2017, time=2017-05-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=196900, encodeId=027d196900b7, content=认真学习,把间接经验应用到临床实践中去,然后再总结出新思路。点赞啦!, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Fri May 12 07:09:10 CST 2017, time=2017-05-12, status=1, ipAttribution=)]
    2017-05-14 ylzr123

    认真学习,把间接经验应用到临床实践中去,然后再总结出新思路。给点赞啦……

    0

  8. 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createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuOWcPEsEP4FrvDcicue5V6rMkmXmY73KjYP59vQrEdjU89iaN4ZkOhsItlHkmGTjhV3b5S3zOQA4E0/0, createdBy=cc261682151, createdName=卡圣, createdTime=Sat May 13 15:41:05 CST 2017, time=2017-05-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=197390, encodeId=462d19e39055, content=白肉比红肉有益的证据。, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Sat May 13 07:12:46 CST 2017, time=2017-05-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=196900, encodeId=027d196900b7, content=认真学习,把间接经验应用到临床实践中去,然后再总结出新思路。点赞啦!, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Fri May 12 07:09:10 CST 2017, time=2017-05-12, status=1, ipAttribution=)]
    2017-05-13 卡圣

    学习了,谢谢

    0

  9. 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createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuOWcPEsEP4FrvDcicue5V6rMkmXmY73KjYP59vQrEdjU89iaN4ZkOhsItlHkmGTjhV3b5S3zOQA4E0/0, createdBy=cc261682151, createdName=卡圣, createdTime=Sat May 13 15:41:05 CST 2017, time=2017-05-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=197390, encodeId=462d19e39055, content=白肉比红肉有益的证据。, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Sat May 13 07:12:46 CST 2017, time=2017-05-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=196900, encodeId=027d196900b7, content=认真学习,把间接经验应用到临床实践中去,然后再总结出新思路。点赞啦!, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Fri May 12 07:09:10 CST 2017, time=2017-05-12, status=1, ipAttribution=)]
    2017-05-13 jyzxjiangqin

    白肉比红肉有益的证据。

    0

  10. 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createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuOWcPEsEP4FrvDcicue5V6rMkmXmY73KjYP59vQrEdjU89iaN4ZkOhsItlHkmGTjhV3b5S3zOQA4E0/0, createdBy=cc261682151, createdName=卡圣, createdTime=Sat May 13 15:41:05 CST 2017, time=2017-05-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=197390, encodeId=462d19e39055, content=白肉比红肉有益的证据。, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Sat May 13 07:12:46 CST 2017, time=2017-05-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=196900, encodeId=027d196900b7, content=认真学习,把间接经验应用到临床实践中去,然后再总结出新思路。点赞啦!, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Fri May 12 07:09:10 CST 2017, time=2017-05-12, status=1, ipAttribution=)]
    2017-05-12 ylzr123

    认真学习,把间接经验应用到临床实践中去,然后再总结出新思路。点赞啦!

    0

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Ann Oncol:大量摄入红肉或使肺癌风险升高

      我国学者近期在《肿瘤学年鉴》(Ann Oncol)发表的一项研究表明,肉类摄入与肺癌风险的相关性可能随摄入肉类不同而不同。大量摄入红肉可能使肺癌风险升高约35%,而大量摄入禽肉可能使这种风险降低约10%。今后需要在更多设计良好的队列研究中评估肉类诱变剂、血红素铁、烹饪方法和成熟度等因素对这一相关性的影响。   很多流行病学研