Eur Radiol:比较MRI结合MRCP与超声内镜鉴别胰腺粘液性肿瘤良恶性的价值。

2017-08-07 shaosai MedSci原创

胰腺导管内乳头状黏液肿瘤(intraductal papillary mucinous neoplasm,IPMN)是一种较少见的胰腺囊性肿瘤。其起源于胰腺导管上皮,呈乳头状生长,分泌过多的黏液,引起主胰管和(或)分支胰管进行性扩张或囊变。IPMN好发于老年人,最多见于6o~7o岁,男女之比约2:1。临床症状和体征取决于导管扩张的程度和产生黏液的量。可表现为上腹部疼痛、乏力,也可因胰液流出受阻产生

胰腺导管内乳头状黏液肿瘤(intraductal papillary mucinous neoplasm,IPMN)是一种较少见的胰腺囊性肿瘤。其起源于胰腺导管上皮,呈乳头状生长,分泌过多的黏液,引起主胰管和(或)分支胰管进行性扩张或囊变。IPMN好发于老年人,最多见于6o~7o岁,男女之比约2:1。临床症状和体征取决于导管扩张的程度和产生黏液的量。可表现为上腹部疼痛、乏力,也可因胰液流出受阻产生慢性胰腺炎甚至急性发作的临床表现。胰腺囊性肿瘤包括胰腺囊腺瘤和胰腺囊腺癌,比较少见。本研究为了比较MRI和超声内镜在鉴别IPMNs和恶性粘液性囊腺肿瘤(MCNs)良恶性的诊断价值并将结果发表在Eur Radiol上。

本研究回顾性分析了55例行增强MRI和EUS的胰腺病变患者,其中有47例经手术确认的IPMNs(12恶性和35例良性)和8例MCNs(2例恶性和6例良性)。在EUS检查中并没有全部进行对比增强。由两名观察者独立评价MRIs,另外评价EUS图像。他们对每一种技术鉴别良恶性的诊断能力进行评分。利用ROC曲线(Az)评价诊断效能,计算准确率、敏感性、特异性、阳性预测值(PPV)和阴性预测值(NPV)。

结果为,MRI的A z 要高于EUS的Az值 (0.712 和 0.688 for MRI vs. 0.543 for EUS; p = 0.007)。 两名观察者MRI诊断准确率 (74.5%)、特异性 (78.0% and 80.5%) 、PPV (50.0%) 要高于EUS(56.4%, 58.5% 和29.2%, respectively) (p = 0.013-0.049)。

本研究表明,MRI对鉴别胰腺IPMN和MCN的良恶性要优于EUS。

原始出处:


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    2017-08-12 王晓霞

    学习

    0

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    2017-08-11 王晓霞

    学习了

    0

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    2017-08-09 docwu2019
  4. 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    2017-08-09 王晓霞

    学习

    0

  5. 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    2017-08-08 月吟凤歌

    一起来学习吧

    0

  6. 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    2017-08-08 xuexin53

    学习

    0

  7. 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attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2017/04/21/72142930668371951a41ef4ea4b233e6.jpg, createdBy=dcbc1715228, createdName=刘煜, createdTime=Tue Aug 08 06:38:38 CST 2017, time=2017-08-08, status=1, ipAttribution=)]
    2017-08-08 胖红

    学习了很多的事情。

    0

  8. 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createdTime=Tue Aug 08 08:12:33 CST 2017, time=2017-08-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=231360, encodeId=d11e23136071, content=学习了很多的事情。, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NcXNhUvfhzd2dD8SUAwqrufRiaKMGaaBScoAzEicJJibuu3wCIWWQxoLgS2UOBx1vsPe3faZtAiatc0pTWlS6868zZH/0, createdBy=0a231960988, createdName=胖红, createdTime=Tue Aug 08 07:23:50 CST 2017, time=2017-08-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=231353, encodeId=04522313536c, content=学习学习学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, 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    2017-08-08 深海的鱼

    学习学习学习

    0

  9. 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attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2017/04/21/72142930668371951a41ef4ea4b233e6.jpg, createdBy=dcbc1715228, createdName=刘煜, createdTime=Tue Aug 08 06:38:38 CST 2017, time=2017-08-08, status=1, ipAttribution=)]
    2017-08-08 衣带渐宽

    学习

    0

  10. 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attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2017/04/21/72142930668371951a41ef4ea4b233e6.jpg, createdBy=dcbc1715228, createdName=刘煜, createdTime=Tue Aug 08 06:38:38 CST 2017, time=2017-08-08, status=1, ipAttribution=)]
    2017-08-08 刘煜

    学习了谢谢分享

    0