左束支起搏有效安全!阜外医院陈柯萍和樊晓寒等Heart Rhythm连发两篇文章

2020-01-06 文韬 中国循环杂志

近期,HeartRhythm杂志新一期杂志刊发了阜外医院陈柯萍和樊晓寒教授为通讯作者的2篇文章。本期杂志的重点是左束支起搏。近端左束支穿行于左室间隔,然后呈扇形散开,这样所形成的起搏区域比希氏束起搏的范围更大。将起搏导线穿过室间隔,放置在室间隔左侧的心内膜下区域,可以实现左束支起搏,有望成为缓慢性心律失常和房室传导阻滞的生理起搏策略。两篇文章都发现,永久性左束支起搏成功率较高,起搏阈值稳定,左心室

近期,HeartRhythm杂志新一期杂志刊发了阜外医院陈柯萍和樊晓寒教授为通讯作者的2篇文章。

本期杂志的重点是左束支起搏。

近端左束支穿行于左室间隔,然后呈扇形散开,这样所形成的起搏区域比希氏束起搏的范围更大。将起搏导线穿过室间隔,放置在室间隔左侧的心内膜下区域,可以实现左束支起搏,有望成为缓慢性心律失常和房室传导阻滞的生理起搏策略。

两篇文章都发现,永久性左束支起搏成功率较高,起搏阈值稳定,左心室同步性好,并发症少。

陈柯萍教授等纳入了87例有起搏适应证的心动过缓患者,67.8%窦房结功能障碍;32.2%房室传导阻滞。

其中,70例左束支起搏成功,其余17例接受了右室间隔起搏。

左束支起搏植入的过程时间平均为18.0分钟,荧光透视时间为3.9分钟。

左束支起搏患者的心电图QRSd较窄,为113.2±9.9 ms,而右心室间隔起搏QRSd为144.4±12.8 ms。两组患者没有严重并发症,起搏阈值很低。

樊晓寒等研究纳入了33例房室传导阻滞并且有心室起搏适应证的病人。

其中30例患者左束支起搏成功,术中QRSd为112.8±10.9 ms,3月随访时为116.8±10.4 ms。

在术后即刻和3个月随访中,夺获阈值也较低。与基线相比,在3月随访时,二维超声心动图应变成像发现,心脏功能和左心室同步略有改善。唯一的并发症是一例患者室间隔穿孔。

来源:

1、Yuqiu Li, et al. Left Bundle Branch Pacing for Symptomatic Bradycardia: Implant Success Rate, Safety, and Pacing Characteristics. Heart Rhythm. 2019; 16 (12), 1758-1765

2、Xiaofei Li, et al. Permanent Left Bundle Branch Area Pacing for Atrioventricular Block: Feasibility, Safety, and Acute Effect. Heart Rhythm; 16 (12), 1766-1773


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    2020-01-08 zhaojie88
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    2020-01-08 slcumt