Fam Pract：抗抑郁药可改善血糖控制

2016-01-19 Mechront 译 MedSci原创

糖尿病患者中抑郁并不少见，此外抑郁还会增加高血糖、发病率和死亡率风险。而目前关于抗抑郁药物（ADM）对血糖控制的影响仍不明确。研究者对同时患有抑郁和2型糖尿病的患者进行了一项研究，探究ADM对血糖控制的影响。该回顾性队列研究共纳入了1399名参与者，根据ICD-9-CM对参与者进行抑郁的诊断；从参与者的处方中识别ADM使用者；当 A1c < 7.0% (53 mmol/mol)时定义为血糖控

糖尿病患者中抑郁并不少见，此外抑郁还会增加高血糖的发病率和死亡率风险。而目前关于抗抑郁药物（ADM）对血糖控制的影响仍不明确。研究者对同时患有抑郁和2型糖尿病的患者进行了一项研究，探究ADM对血糖控制的影响。

该回顾性队列研究共纳入了1399名参与者，根据ICD-9-CM对参与者进行抑郁的诊断；从参与者的处方中识别ADM使用者；当 A1c < 7.0% (53 mmol/mol)时定义为血糖控制良好。

研究数据形式，使用ADM治疗的抑郁患者中有50.9%的患者血糖控制好，没有使用ALM治疗的抑郁患者中该值为34.6%。校正混杂因素后，接受ADM治疗的抑郁患者血糖控制好的可能性是不使用ADM治疗抑郁症患者的两倍左右(OR= 1.95; 95% CI: 1.02-3.71)。

该大样本的回顾性队列研究表明，2型糖尿病患者中抑郁症者使用抗抑郁药物，可改善血糖控制情况。

原始出处：

Brieler JA1, Lustman PJ.et al.Antidepressant medication use and glycaemic control in co-morbid type 2 diabetes and depression.Fam Pract. 2016 Jan 7. pii: cmv100. [Epub ahead of print]

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#插入话题

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2016-11-05 wetgdt

#抑郁药#

29 0
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2016-01-29 circlegirl

综合管理

161 0
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2016-01-27 doctording1

不错，赞一个

102 0
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2016-01-27 doctording1

这篇文章有一定深度

134 0
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2016-01-27 doctording1

是一篇不错的文章

114 0
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2016-01-27 doctording1

值得进一步关注

101 0
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2016-01-27 李继凯

好好学习

79 0
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2016-01-27 李继凯

赞一个

102 0
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2016-01-27 mingliqinmian

我仔细看看

79 0
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2016-01-25 I come

客观

94 0

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