JAHA:妊娠期高血压与心血管疾病风险的关系!

2018-05-14 xing.T MedSci原创

由此可见,GH与随后的CVD风险增加有关,当GH合并小于胎龄儿和/或早产同时发生时,CVD的风险最高。

先兆子痫和妊娠高血压(GH)是最常见的妊娠期高血压性疾病。先兆子痫与心血管疾病(CVD)风险增加有关,但GH与其是否有类似的关联尚不明确。近日,心血管疾病领域权威杂志JAHA上发表了一篇研究文章,研究人员的目的是明确GH和随后CVD之间的关联,并探讨其对小于胎龄儿、早产和产次的附加作用。

研究人员将来自于挪威医疗出生登记中心的数据与挪威心血管疾病项目和挪威死因登记中心的数据链接,使用Cox比例风险回归计算了风险比和95%可信区间,比较了第一次和/或第二次妊娠期间有GH和没有GH的妇女。

研究人员纳入了所有从1980到2009的第一次分娩的妇女(n=617589),并对其随访中位数为14.3年(四分位数1-四分位数3为:6.9-21.5)。与没有任何妊娠高血压疾病的妇女相比,第一次妊娠的GH患者后续发生CVD的风险增加1.8倍(95%可信区间为1.7-2)。当GH与小于胎龄儿和/或早产同时发生时,风险比为2.6(95%可信区间为2.3-3)。当GH的妇女与先兆子痫的妇女相比,当妊娠并发症发生在第一或第二次妊娠时,CVD的风险相当,但在两次妊娠中发生紊乱时无并发症的先兆子痫风险显著增高。

由此可见,GH与随后的CVD风险增加有关,当GH合并小于胎龄儿和/或早产同时发生时,CVD的风险最高。

原始出处:

Hilde Kristin Refvik Riise,et al. Association Between Gestational Hypertension and Risk of Cardiovascular Disease Among 617 589 Norwegian Women, JAHA.2018. https://doi.org/10.1161/JAHA.117.008337

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    2018-05-16 仁者大医
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time=2018-05-14, status=1, ipAttribution=)]
  5. 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time=2018-05-14, status=1, ipAttribution=)]
  6. 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encodeId=d3f43153945a, content=学习一下很不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zMoyicyo6ia9f4IuLQAwZoxD6Hx4ibd5CMcOCYhStY6oDibbKK6O2X8iaicldO5ib8j1iapOIobIKCGiczU2A/0, createdBy=56251941490, createdName=虈亣靌, createdTime=Tue May 15 19:00:15 CST 2018, time=2018-05-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=315147, encodeId=54ac31514e48, content=学习了.谢谢分享., beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/xkvRjYnJzzRJ2R0y7VhicibvkjPWHjIMmu4ZpKnE9cWAu4lVicS3uDUCfF4M4JWvrkrYfpb2KehPV0Ee29tPqyPEebBUibiaKhnvD/0, createdBy=f8412001184, createdName=惠映实验室, createdTime=Mon May 14 23:42:10 CST 2018, time=2018-05-14, status=1, ipAttribution=)]
    2018-05-16 大爰

    学习了谢谢分享!!

    0

  7. 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time=2018-05-14, status=1, ipAttribution=)]
    2018-05-15 惠映实验室

    学习了.谢谢分享.

    0

  8. 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encodeId=d3f43153945a, content=学习一下很不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zMoyicyo6ia9f4IuLQAwZoxD6Hx4ibd5CMcOCYhStY6oDibbKK6O2X8iaicldO5ib8j1iapOIobIKCGiczU2A/0, createdBy=56251941490, createdName=虈亣靌, createdTime=Tue May 15 19:00:15 CST 2018, time=2018-05-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=315147, encodeId=54ac31514e48, content=学习了.谢谢分享., beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/xkvRjYnJzzRJ2R0y7VhicibvkjPWHjIMmu4ZpKnE9cWAu4lVicS3uDUCfF4M4JWvrkrYfpb2KehPV0Ee29tPqyPEebBUibiaKhnvD/0, createdBy=f8412001184, createdName=惠映实验室, createdTime=Mon May 14 23:42:10 CST 2018, time=2018-05-14, status=1, ipAttribution=)]
    2018-05-15 虈亣靌

    学习一下很不错

    0

  9. 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time=2018-05-14, status=1, ipAttribution=)]
    2018-05-14 惠映实验室

    学习了.谢谢分享.

    0

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