Stroke:颅内动脉狭窄及其与一般人群常规危险因素的关系

2019-07-23 xing.T MedSci原创

在这个以社区为基础的日本男性样本中,ICAS估计占25.2%,除高血压和年龄外,还与代谢危险因素有关。这些结果支持全面管理常规心血管危险因素对卒中预防的重要性。

很少有基于社区的研究报道用磁共振血管造影评估颅内动脉狭窄(ICAS)的患病率。近日,心血管疾病领域权威杂志Stroke上发表了一篇研究文章,该研究旨在一般日本男性人群中使用磁共振血管造影确定ICAS的患病率,并探究ICAS与常规心血管危险因素之间的关联。 

2006年至2008年,研究人员随机招募并评估了亚临床动脉粥样硬化的志贺流行病学研究(基线,2012年至2015年)中来自日本滋贺县草津市的参与者;740名男性进行随访并接受1.5T脑磁共振血管造影检查。参与者被分类为无ICAS、轻度ICAS(1-50%)或严重ICAS(≥50%)。在排除有卒中病史的男性后,研究人员使用多变量logistic回归分析了709名男性,以评估常规心血管危险因素的独立关联,参考组为无ICAS组。 

参与者的平均年龄为68.0岁。轻度和重度ICAS的年龄标准化患病率分别为20.7%和4.5%(以2010年日本人口统计数据的人口为参考)。在同时调整常规心血管危险因素后,年龄、高血压糖尿病和血脂异常与严重ICAS的患病率较高有关。

在这个以社区为基础的日本男性样本中,ICAS估计占25.2%,除高血压和年龄外,还与代谢危险因素有关。这些结果支持全面管理常规心血管危险因素对卒中预防的重要性。 

原始出处:

Satoshi Shitara.et al.Intracranial Artery Stenosis and Its Association With Conventional Risk Factors in a General Population of Japanese Men.stroke.2019.https://www.ahajournals.org/doi/10.1161/STROKEAHA.119.025964

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    2019-07-28 一天没事干

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    2019-07-27 一天没事干

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    2019-07-26 一天没事干

    很好的学习机会

    0

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