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Trovagene在ASCO-GU会议上介绍了Onvansertib与Zytiga联合治疗mCRPC的II期研究

2019-02-18 不详 网络

OnvansertibZytiga转移性去势抵抗性前列腺癌
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Trovagene是一家临床阶段肿瘤治疗公司，采用精准医学方法开发白血病、淋巴瘤和实体瘤癌症的治疗药物，Trovagene近日在加利福尼亚州旧金山的Genitourinary Cancer Symposium（ASCO-GU）会议上公布了正在进行的第II阶段研究，该研究评估了Onvansertib与Zytiga（醋酸阿比特龙）联合治疗转移性去势抵抗性前列腺癌（mCRPC）患者的安全性和耐受性。

Trovagene是一家临床阶段肿瘤治疗公司，采用精准医学方法开发白血病、淋巴瘤和实体瘤癌症的治疗药物，Trovagene近日在加利福尼亚州旧金山的Genitourinary Cancer Symposium（ASCO-GU）会议上公布了正在进行的第II阶段研究，该研究评估了Onvansertib与Zytiga（醋酸阿比特龙）联合治疗转移性去势抵抗性前列腺癌（mCRPC）患者的安全性和耐受性。这些数据在Genitourinary Cancer Symposium（ASCO-GU）的海报中展示，证明了Onvansertib与Zytiga联合使用的安全性和耐受性。

去势抵抗性前列腺癌（CRPC）是指经过初次持续雄激素剥夺治疗（ADT）后疾病依然进展的前列腺癌，根据2014年中国泌尿科学会的指南，诊断CRPC需符合以下4个条件：1、血清睾酮达到去势水平（<50ng/dl 或<1.7nmol/L）；2、间隔一周、连续三次PSA升高，且较最低值升高大于50%；3、传统抗雄药物撤退治疗失败；4、有骨或软组织转移病变的进展。几乎所有的晚期前列腺癌患者在接受内分泌治疗后，都会最终进展为去势抵抗性前列腺癌（CPRC）。


原始出处：

http://www.firstwordpharma.com/node/1625336#axzz5fc4uA1RS

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    2020-02-03 quxin068

    #ASC#

    0

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    2019-05-16 lfcmxl

    #Trovagene#

    0

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time=2019-02-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=360949, encodeId=9f2d360949fb, content=真不错，连生物标志物的检测阀值都给出来了, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/02/18/81ff04c53a66053ece2d1fb796d2dac0.jpg, createdBy=cc1c2549075, createdName=maomao2019, createdTime=Mon Feb 18 17:13:25 CST 2019, time=2019-02-18, status=1, ipAttribution=)]
    2019-02-28 cy0324

    #Gene#

    0

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encryptionId=ca6952e52f, topicName=CRP)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e1cc90, createdName=rebeccajiejie, createdTime=Wed Feb 20 07:56:00 CST 2019, time=2019-02-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1313733, encodeId=ffdd1313e3359, content=<a href='/topic/show?id=d4cc80e128f' target=_blank style='color:#2F92EE;'>#联合治疗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=80712, encryptionId=d4cc80e128f, topicName=联合治疗)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=263b421, createdName=zhaozuguo, createdTime=Wed Feb 20 07:56:00 CST 2019, time=2019-02-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1466230, encodeId=f85a146623001, content=<a href='/topic/show?id=56fb19113a3' target=_blank style='color:#2F92EE;'>#Zytiga#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=19113, encryptionId=56fb19113a3, topicName=Zytiga)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=82186780852, createdName=lqrandywkz, createdTime=Wed Feb 20 07:56:00 CST 2019, time=2019-02-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1503921, encodeId=cf6e1503921f2, content=<a href='/topic/show?id=641d94e7eb' target=_blank style='color:#2F92EE;'>#IgA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=9477, encryptionId=641d94e7eb, topicName=IgA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c23f9697922, createdName=yibei, createdTime=Wed Feb 20 07:56:00 CST 2019, time=2019-02-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1555938, encodeId=2bb415559389b, content=<a href='/topic/show?id=641e1139ea8' target=_blank style='color:#2F92EE;'>#mCRPC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11397, encryptionId=641e1139ea8, topicName=mCRPC)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d48314676153, createdName=liuquanmn, createdTime=Wed Feb 20 07:56:00 CST 2019, time=2019-02-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1569855, encodeId=69d615698558e, content=<a href='/topic/show?id=bc1352e951' target=_blank style='color:#2F92EE;'>#CRPC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5279, encryptionId=bc1352e951, topicName=CRPC)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=5daa15584462, createdName=flyingeagle82, createdTime=Wed Feb 20 07:56:00 CST 2019, time=2019-02-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=360949, encodeId=9f2d360949fb, content=真不错，连生物标志物的检测阀值都给出来了, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/02/18/81ff04c53a66053ece2d1fb796d2dac0.jpg, createdBy=cc1c2549075, createdName=maomao2019, createdTime=Mon Feb 18 17:13:25 CST 2019, time=2019-02-18, status=1, ipAttribution=)]
    2019-02-20 rebeccajiejie

    #CRP#

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=1938922, encodeId=96741938922e9, content=<a href='/topic/show?id=1c292818fd' target=_blank style='color:#2F92EE;'>#ASC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2818, encryptionId=1c292818fd, topicName=ASC)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=74808, createdName=quxin068, createdTime=Mon Feb 03 02:56:00 CST 2020, time=2020-02-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2049789, encodeId=870f2049e89fc, content=<a href='/topic/show?id=05ea1e8500a' target=_blank style='color:#2F92EE;'>#Trovagene#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=17850, encryptionId=05ea1e8500a, topicName=Trovagene)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=da20314, createdName=lfcmxl, createdTime=Thu May 16 17:56:00 CST 2019, time=2019-05-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2049149, encodeId=182120491490c, content=<a href='/topic/show?id=4363e929ad' target=_blank style='color:#2F92EE;'>#Gene#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7929, encryptionId=4363e929ad, topicName=Gene)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=63a4277, createdName=cy0324, createdTime=Thu Feb 28 15:56:00 CST 2019, time=2019-02-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1269610, encodeId=8fac12696107e, content=<a href='/topic/show?id=ca6952e52f' target=_blank style='color:#2F92EE;'>#CRP#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5275, encryptionId=ca6952e52f, topicName=CRP)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e1cc90, createdName=rebeccajiejie, createdTime=Wed Feb 20 07:56:00 CST 2019, time=2019-02-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1313733, encodeId=ffdd1313e3359, content=<a href='/topic/show?id=d4cc80e128f' target=_blank style='color:#2F92EE;'>#联合治疗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=80712, encryptionId=d4cc80e128f, topicName=联合治疗)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=263b421, createdName=zhaozuguo, createdTime=Wed Feb 20 07:56:00 CST 2019, time=2019-02-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1466230, encodeId=f85a146623001, content=<a href='/topic/show?id=56fb19113a3' target=_blank style='color:#2F92EE;'>#Zytiga#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=19113, encryptionId=56fb19113a3, topicName=Zytiga)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=82186780852, createdName=lqrandywkz, createdTime=Wed Feb 20 07:56:00 CST 2019, time=2019-02-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1503921, encodeId=cf6e1503921f2, content=<a href='/topic/show?id=641d94e7eb' target=_blank style='color:#2F92EE;'>#IgA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=9477, encryptionId=641d94e7eb, topicName=IgA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c23f9697922, createdName=yibei, createdTime=Wed Feb 20 07:56:00 CST 2019, time=2019-02-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1555938, encodeId=2bb415559389b, content=<a href='/topic/show?id=641e1139ea8' target=_blank style='color:#2F92EE;'>#mCRPC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11397, encryptionId=641e1139ea8, topicName=mCRPC)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d48314676153, createdName=liuquanmn, createdTime=Wed Feb 20 07:56:00 CST 2019, time=2019-02-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1569855, encodeId=69d615698558e, content=<a href='/topic/show?id=bc1352e951' target=_blank style='color:#2F92EE;'>#CRPC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5279, encryptionId=bc1352e951, topicName=CRPC)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=5daa15584462, createdName=flyingeagle82, createdTime=Wed Feb 20 07:56:00 CST 2019, time=2019-02-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=360949, encodeId=9f2d360949fb, content=真不错，连生物标志物的检测阀值都给出来了, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/02/18/81ff04c53a66053ece2d1fb796d2dac0.jpg, createdBy=cc1c2549075, createdName=maomao2019, createdTime=Mon Feb 18 17:13:25 CST 2019, time=2019-02-18, status=1, ipAttribution=)]
    2019-02-20 zhaozuguo

    #联合治疗#

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1938922, encodeId=96741938922e9, content=<a href='/topic/show?id=1c292818fd' target=_blank style='color:#2F92EE;'>#ASC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2818, encryptionId=1c292818fd, topicName=ASC)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=74808, createdName=quxin068, createdTime=Mon Feb 03 02:56:00 CST 2020, time=2020-02-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2049789, encodeId=870f2049e89fc, content=<a href='/topic/show?id=05ea1e8500a' target=_blank style='color:#2F92EE;'>#Trovagene#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=17850, encryptionId=05ea1e8500a, topicName=Trovagene)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=da20314, createdName=lfcmxl, createdTime=Thu May 16 17:56:00 CST 2019, time=2019-05-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2049149, encodeId=182120491490c, content=<a href='/topic/show?id=4363e929ad' target=_blank style='color:#2F92EE;'>#Gene#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7929, encryptionId=4363e929ad, topicName=Gene)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=63a4277, createdName=cy0324, createdTime=Thu Feb 28 15:56:00 CST 2019, time=2019-02-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1269610, encodeId=8fac12696107e, content=<a href='/topic/show?id=ca6952e52f' target=_blank style='color:#2F92EE;'>#CRP#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5275, encryptionId=ca6952e52f, topicName=CRP)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e1cc90, createdName=rebeccajiejie, createdTime=Wed Feb 20 07:56:00 CST 2019, time=2019-02-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1313733, encodeId=ffdd1313e3359, content=<a href='/topic/show?id=d4cc80e128f' target=_blank style='color:#2F92EE;'>#联合治疗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=80712, encryptionId=d4cc80e128f, topicName=联合治疗)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=263b421, createdName=zhaozuguo, createdTime=Wed Feb 20 07:56:00 CST 2019, time=2019-02-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1466230, encodeId=f85a146623001, content=<a href='/topic/show?id=56fb19113a3' target=_blank style='color:#2F92EE;'>#Zytiga#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=19113, encryptionId=56fb19113a3, topicName=Zytiga)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=82186780852, createdName=lqrandywkz, createdTime=Wed Feb 20 07:56:00 CST 2019, time=2019-02-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1503921, encodeId=cf6e1503921f2, content=<a href='/topic/show?id=641d94e7eb' target=_blank style='color:#2F92EE;'>#IgA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=9477, encryptionId=641d94e7eb, topicName=IgA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c23f9697922, createdName=yibei, createdTime=Wed Feb 20 07:56:00 CST 2019, time=2019-02-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1555938, encodeId=2bb415559389b, content=<a href='/topic/show?id=641e1139ea8' target=_blank style='color:#2F92EE;'>#mCRPC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11397, encryptionId=641e1139ea8, topicName=mCRPC)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d48314676153, createdName=liuquanmn, createdTime=Wed Feb 20 07:56:00 CST 2019, time=2019-02-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1569855, encodeId=69d615698558e, content=<a href='/topic/show?id=bc1352e951' target=_blank style='color:#2F92EE;'>#CRPC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5279, encryptionId=bc1352e951, topicName=CRPC)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=5daa15584462, createdName=flyingeagle82, createdTime=Wed Feb 20 07:56:00 CST 2019, time=2019-02-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=360949, encodeId=9f2d360949fb, content=真不错，连生物标志物的检测阀值都给出来了, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/02/18/81ff04c53a66053ece2d1fb796d2dac0.jpg, createdBy=cc1c2549075, createdName=maomao2019, createdTime=Mon Feb 18 17:13:25 CST 2019, time=2019-02-18, status=1, ipAttribution=)]
    2019-02-20 lqrandywkz

    #Zytiga#

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=1938922, encodeId=96741938922e9, content=<a href='/topic/show?id=1c292818fd' target=_blank style='color:#2F92EE;'>#ASC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2818, encryptionId=1c292818fd, topicName=ASC)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=74808, createdName=quxin068, createdTime=Mon Feb 03 02:56:00 CST 2020, time=2020-02-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2049789, encodeId=870f2049e89fc, content=<a href='/topic/show?id=05ea1e8500a' target=_blank style='color:#2F92EE;'>#Trovagene#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=17850, encryptionId=05ea1e8500a, topicName=Trovagene)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=da20314, createdName=lfcmxl, createdTime=Thu May 16 17:56:00 CST 2019, time=2019-05-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2049149, encodeId=182120491490c, content=<a href='/topic/show?id=4363e929ad' target=_blank style='color:#2F92EE;'>#Gene#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7929, encryptionId=4363e929ad, topicName=Gene)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=63a4277, createdName=cy0324, createdTime=Thu Feb 28 15:56:00 CST 2019, time=2019-02-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1269610, encodeId=8fac12696107e, content=<a href='/topic/show?id=ca6952e52f' target=_blank style='color:#2F92EE;'>#CRP#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5275, encryptionId=ca6952e52f, topicName=CRP)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e1cc90, createdName=rebeccajiejie, createdTime=Wed Feb 20 07:56:00 CST 2019, time=2019-02-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1313733, encodeId=ffdd1313e3359, content=<a href='/topic/show?id=d4cc80e128f' target=_blank style='color:#2F92EE;'>#联合治疗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=80712, encryptionId=d4cc80e128f, topicName=联合治疗)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=263b421, createdName=zhaozuguo, createdTime=Wed Feb 20 07:56:00 CST 2019, time=2019-02-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1466230, encodeId=f85a146623001, content=<a href='/topic/show?id=56fb19113a3' target=_blank style='color:#2F92EE;'>#Zytiga#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=19113, encryptionId=56fb19113a3, topicName=Zytiga)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=82186780852, createdName=lqrandywkz, createdTime=Wed Feb 20 07:56:00 CST 2019, time=2019-02-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1503921, encodeId=cf6e1503921f2, content=<a href='/topic/show?id=641d94e7eb' target=_blank style='color:#2F92EE;'>#IgA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=9477, encryptionId=641d94e7eb, topicName=IgA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c23f9697922, createdName=yibei, createdTime=Wed Feb 20 07:56:00 CST 2019, time=2019-02-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1555938, encodeId=2bb415559389b, content=<a href='/topic/show?id=641e1139ea8' target=_blank style='color:#2F92EE;'>#mCRPC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11397, encryptionId=641e1139ea8, topicName=mCRPC)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d48314676153, createdName=liuquanmn, createdTime=Wed Feb 20 07:56:00 CST 2019, time=2019-02-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1569855, encodeId=69d615698558e, content=<a href='/topic/show?id=bc1352e951' target=_blank style='color:#2F92EE;'>#CRPC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5279, encryptionId=bc1352e951, topicName=CRPC)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=5daa15584462, createdName=flyingeagle82, createdTime=Wed Feb 20 07:56:00 CST 2019, time=2019-02-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=360949, encodeId=9f2d360949fb, content=真不错，连生物标志物的检测阀值都给出来了, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/02/18/81ff04c53a66053ece2d1fb796d2dac0.jpg, createdBy=cc1c2549075, createdName=maomao2019, createdTime=Mon Feb 18 17:13:25 CST 2019, time=2019-02-18, status=1, ipAttribution=)]
    2019-02-20 yibei

    #IgA#

    0

  8. [GetPortalCommentsPageByObjectIdResponse(id=1938922, encodeId=96741938922e9, content=<a href='/topic/show?id=1c292818fd' target=_blank style='color:#2F92EE;'>#ASC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2818, encryptionId=1c292818fd, topicName=ASC)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=74808, createdName=quxin068, createdTime=Mon Feb 03 02:56:00 CST 2020, time=2020-02-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2049789, encodeId=870f2049e89fc, content=<a href='/topic/show?id=05ea1e8500a' target=_blank style='color:#2F92EE;'>#Trovagene#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=17850, encryptionId=05ea1e8500a, topicName=Trovagene)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=da20314, createdName=lfcmxl, createdTime=Thu May 16 17:56:00 CST 2019, time=2019-05-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2049149, encodeId=182120491490c, content=<a href='/topic/show?id=4363e929ad' target=_blank style='color:#2F92EE;'>#Gene#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7929, encryptionId=4363e929ad, topicName=Gene)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=63a4277, createdName=cy0324, createdTime=Thu Feb 28 15:56:00 CST 2019, time=2019-02-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1269610, encodeId=8fac12696107e, content=<a href='/topic/show?id=ca6952e52f' target=_blank style='color:#2F92EE;'>#CRP#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5275, encryptionId=ca6952e52f, topicName=CRP)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e1cc90, createdName=rebeccajiejie, createdTime=Wed Feb 20 07:56:00 CST 2019, time=2019-02-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1313733, encodeId=ffdd1313e3359, content=<a href='/topic/show?id=d4cc80e128f' target=_blank style='color:#2F92EE;'>#联合治疗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=80712, encryptionId=d4cc80e128f, topicName=联合治疗)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=263b421, createdName=zhaozuguo, createdTime=Wed Feb 20 07:56:00 CST 2019, time=2019-02-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1466230, encodeId=f85a146623001, content=<a href='/topic/show?id=56fb19113a3' target=_blank style='color:#2F92EE;'>#Zytiga#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=19113, encryptionId=56fb19113a3, topicName=Zytiga)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=82186780852, createdName=lqrandywkz, createdTime=Wed Feb 20 07:56:00 CST 2019, time=2019-02-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1503921, encodeId=cf6e1503921f2, content=<a href='/topic/show?id=641d94e7eb' target=_blank style='color:#2F92EE;'>#IgA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=9477, encryptionId=641d94e7eb, topicName=IgA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c23f9697922, createdName=yibei, createdTime=Wed Feb 20 07:56:00 CST 2019, time=2019-02-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1555938, encodeId=2bb415559389b, content=<a href='/topic/show?id=641e1139ea8' target=_blank style='color:#2F92EE;'>#mCRPC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11397, encryptionId=641e1139ea8, topicName=mCRPC)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d48314676153, createdName=liuquanmn, createdTime=Wed Feb 20 07:56:00 CST 2019, time=2019-02-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1569855, encodeId=69d615698558e, content=<a href='/topic/show?id=bc1352e951' target=_blank style='color:#2F92EE;'>#CRPC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5279, encryptionId=bc1352e951, topicName=CRPC)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=5daa15584462, createdName=flyingeagle82, createdTime=Wed Feb 20 07:56:00 CST 2019, time=2019-02-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=360949, encodeId=9f2d360949fb, content=真不错，连生物标志物的检测阀值都给出来了, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/02/18/81ff04c53a66053ece2d1fb796d2dac0.jpg, createdBy=cc1c2549075, createdName=maomao2019, createdTime=Mon Feb 18 17:13:25 CST 2019, time=2019-02-18, status=1, ipAttribution=)]
    2019-02-20 liuquanmn

    #mCRPC#

    0

  9. [GetPortalCommentsPageByObjectIdResponse(id=1938922, encodeId=96741938922e9, content=<a href='/topic/show?id=1c292818fd' target=_blank style='color:#2F92EE;'>#ASC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2818, encryptionId=1c292818fd, topicName=ASC)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=74808, createdName=quxin068, createdTime=Mon Feb 03 02:56:00 CST 2020, time=2020-02-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2049789, encodeId=870f2049e89fc, content=<a href='/topic/show?id=05ea1e8500a' target=_blank style='color:#2F92EE;'>#Trovagene#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=17850, encryptionId=05ea1e8500a, topicName=Trovagene)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=da20314, createdName=lfcmxl, createdTime=Thu May 16 17:56:00 CST 2019, time=2019-05-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2049149, encodeId=182120491490c, content=<a href='/topic/show?id=4363e929ad' target=_blank style='color:#2F92EE;'>#Gene#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7929, encryptionId=4363e929ad, topicName=Gene)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=63a4277, createdName=cy0324, createdTime=Thu Feb 28 15:56:00 CST 2019, time=2019-02-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1269610, encodeId=8fac12696107e, content=<a href='/topic/show?id=ca6952e52f' target=_blank style='color:#2F92EE;'>#CRP#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5275, encryptionId=ca6952e52f, topicName=CRP)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e1cc90, createdName=rebeccajiejie, createdTime=Wed Feb 20 07:56:00 CST 2019, time=2019-02-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1313733, encodeId=ffdd1313e3359, content=<a href='/topic/show?id=d4cc80e128f' target=_blank style='color:#2F92EE;'>#联合治疗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=80712, encryptionId=d4cc80e128f, topicName=联合治疗)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=263b421, createdName=zhaozuguo, createdTime=Wed Feb 20 07:56:00 CST 2019, time=2019-02-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1466230, encodeId=f85a146623001, content=<a href='/topic/show?id=56fb19113a3' target=_blank style='color:#2F92EE;'>#Zytiga#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=19113, encryptionId=56fb19113a3, topicName=Zytiga)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=82186780852, createdName=lqrandywkz, createdTime=Wed Feb 20 07:56:00 CST 2019, time=2019-02-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1503921, encodeId=cf6e1503921f2, content=<a href='/topic/show?id=641d94e7eb' target=_blank style='color:#2F92EE;'>#IgA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=9477, encryptionId=641d94e7eb, topicName=IgA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c23f9697922, createdName=yibei, createdTime=Wed Feb 20 07:56:00 CST 2019, time=2019-02-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1555938, encodeId=2bb415559389b, content=<a href='/topic/show?id=641e1139ea8' target=_blank style='color:#2F92EE;'>#mCRPC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11397, encryptionId=641e1139ea8, topicName=mCRPC)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d48314676153, createdName=liuquanmn, createdTime=Wed Feb 20 07:56:00 CST 2019, time=2019-02-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1569855, encodeId=69d615698558e, content=<a href='/topic/show?id=bc1352e951' target=_blank style='color:#2F92EE;'>#CRPC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5279, encryptionId=bc1352e951, topicName=CRPC)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=5daa15584462, createdName=flyingeagle82, createdTime=Wed Feb 20 07:56:00 CST 2019, time=2019-02-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=360949, encodeId=9f2d360949fb, content=真不错，连生物标志物的检测阀值都给出来了, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/02/18/81ff04c53a66053ece2d1fb796d2dac0.jpg, createdBy=cc1c2549075, createdName=maomao2019, createdTime=Mon Feb 18 17:13:25 CST 2019, time=2019-02-18, status=1, ipAttribution=)]
    2019-02-20 flyingeagle82

    #CRPC#

    0

  10. [GetPortalCommentsPageByObjectIdResponse(id=1938922, encodeId=96741938922e9, content=<a href='/topic/show?id=1c292818fd' target=_blank style='color:#2F92EE;'>#ASC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2818, encryptionId=1c292818fd, topicName=ASC)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=74808, createdName=quxin068, createdTime=Mon Feb 03 02:56:00 CST 2020, time=2020-02-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2049789, encodeId=870f2049e89fc, content=<a href='/topic/show?id=05ea1e8500a' target=_blank style='color:#2F92EE;'>#Trovagene#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=17850, encryptionId=05ea1e8500a, topicName=Trovagene)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=da20314, createdName=lfcmxl, createdTime=Thu May 16 17:56:00 CST 2019, time=2019-05-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2049149, encodeId=182120491490c, content=<a href='/topic/show?id=4363e929ad' target=_blank style='color:#2F92EE;'>#Gene#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7929, encryptionId=4363e929ad, topicName=Gene)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=63a4277, createdName=cy0324, createdTime=Thu Feb 28 15:56:00 CST 2019, time=2019-02-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1269610, encodeId=8fac12696107e, content=<a href='/topic/show?id=ca6952e52f' target=_blank style='color:#2F92EE;'>#CRP#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5275, encryptionId=ca6952e52f, topicName=CRP)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e1cc90, createdName=rebeccajiejie, createdTime=Wed Feb 20 07:56:00 CST 2019, time=2019-02-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1313733, encodeId=ffdd1313e3359, content=<a href='/topic/show?id=d4cc80e128f' target=_blank style='color:#2F92EE;'>#联合治疗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=80712, encryptionId=d4cc80e128f, topicName=联合治疗)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=263b421, createdName=zhaozuguo, createdTime=Wed Feb 20 07:56:00 CST 2019, time=2019-02-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1466230, encodeId=f85a146623001, content=<a href='/topic/show?id=56fb19113a3' target=_blank style='color:#2F92EE;'>#Zytiga#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=19113, encryptionId=56fb19113a3, topicName=Zytiga)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=82186780852, createdName=lqrandywkz, createdTime=Wed Feb 20 07:56:00 CST 2019, time=2019-02-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1503921, encodeId=cf6e1503921f2, content=<a href='/topic/show?id=641d94e7eb' target=_blank style='color:#2F92EE;'>#IgA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=9477, encryptionId=641d94e7eb, topicName=IgA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c23f9697922, createdName=yibei, createdTime=Wed Feb 20 07:56:00 CST 2019, time=2019-02-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1555938, encodeId=2bb415559389b, content=<a href='/topic/show?id=641e1139ea8' target=_blank style='color:#2F92EE;'>#mCRPC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11397, encryptionId=641e1139ea8, topicName=mCRPC)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d48314676153, createdName=liuquanmn, createdTime=Wed Feb 20 07:56:00 CST 2019, time=2019-02-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1569855, encodeId=69d615698558e, content=<a href='/topic/show?id=bc1352e951' target=_blank style='color:#2F92EE;'>#CRPC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5279, encryptionId=bc1352e951, topicName=CRPC)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=5daa15584462, createdName=flyingeagle82, createdTime=Wed Feb 20 07:56:00 CST 2019, time=2019-02-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=360949, encodeId=9f2d360949fb, content=真不错，连生物标志物的检测阀值都给出来了, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/02/18/81ff04c53a66053ece2d1fb796d2dac0.jpg, createdBy=cc1c2549075, createdName=maomao2019, createdTime=Mon Feb 18 17:13:25 CST 2019, time=2019-02-18, status=1, ipAttribution=)]
    2019-02-18 maomao2019

    真不错，连生物标志物的检测阀值都给出来了

    0

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