Obstet Gynecol:慢性高血压孕妇分娩时机

2018-08-11 xing.T MedSci原创

由此可见,该研究结果表明,在患有孤立性慢性高血压的女性中,妊娠38或39周引产可以预防严重的高血压并发症,而不会增加剖宫产的风险。

近日,妇产科权威杂志Obstetrics and Gynecology上发表了一研究文章,研究人员旨在评估慢性高血压妇女在妊娠38或39周时常规引产是否与先兆子痫或剖宫产的风险相关。

研究人员对2012年至2016年期间在加拿大安大略省妊娠38周0/7天的单胎医院分娩的慢性高血压妇女进行了一项基于人群的回顾性研究。在妊娠38周0天至6/7天进行引产的妊娠期慢性高血压患者(n=281)与那些在相应妊娠期间进行待产的孕妇进行比较,并在妊娠39周0/7天时仍未分娩(n=1606)。另外,研究人员将在妊娠39周0/7天至39周6/7天对慢性高血压患者(n=259)进行分娩引产的女性与在妊娠40周0/7天时仍未分娩的孕妇(n=801)进行比较。

在研究期间,534529名孕妇进行了分娩,6054名(1.1%)孕妇患有慢性高血压,2420名孕妇符合入选标准。妊娠38或39周的待产孕妇新发先兆子痫的风险(分别为19.2%[308/1606]和19.0%[152/801])和子痫的风险(分别为0.6%[10/1606]和0.7%[6/801]),超过一半的孕妇在妊娠后期分别进行分娩(分别为56.8%和57.8%)。在引产组中剖宫产的风险较低(妊娠38周)或相应的妊娠时间的待产孕妇类似(妊娠39周)(妊娠38周时为17.1% vs. 34%,相对调整后的风险为0.74 [95%CI为0.57-0.95];妊娠39周:20.1% vs. 26.0%,调整相对风险为0.90 [95%CI为0.69-1.17])。

由此可见,该研究结果表明,在患有孤立性慢性高血压的女性中,妊娠38或39周引产可以预防严重的高血压并发症,而不会增加剖宫产的风险。

原始出处:

Ram, Maya,et al. Timing of Delivery in Women With Chronic Hypertension.Obstetrics & Gynecology.2018.https://journals.lww.com/greenjournal/Abstract/publishahead/Timing_of_Delivery_in_Women_With_Chronic.97991.aspx

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    2019-07-03 yhy100200
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    2018-08-13 linlin2312
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