JAMA SURG:择期手术患者吸烟情况、术前呼出一氧化碳水平与术后手术部位感染之间的关系

2017-05-23 MedSci MedSci原创

吸烟是许多围手术期并发症的危险因素,包括手术部位感染(SSI)。JAMA SURG上近期发表了一篇文章,研究吸烟患者手术当天戒烟与SSI发病率降低之间的关系,研究经过变量(如BMI)调整后吸烟是否与SSI显着相关。

吸烟是许多围手术期并发症的危险因素,包括手术部位感染(SSI)。JAMA SURG上近期发表了一篇文章,研究吸烟患者手术当天戒烟与SSI发病率降低之间的关系,研究经过变量(如BMI)调整后吸烟是否与SSI显着相关。

研究的主要暴露因素为吸烟情况及术前呼出一氧化碳水平,一氧化碳水平有护士测量。如果患者在手术当天自述吸烟或术前呼出一氧化碳水平高于10ppm则认为患者手术当天吸烟。主要的研究结果为术后手术部位感染情况。在第一项研究的6919例患者中,3282例为男性,3637例为女性。对照组及SSI组的平均年龄为60岁。第二项研究的392例患者中,182例为男性,210例为女性。对照组平均年龄53岁,SSI组平均年龄51岁。在研究期间,每年约2%的患者出现出现SSI。2452例SSI患者及相匹配的4467例对照患者进行第一项研究,评估吸烟的影响。吸烟与SSI的OR值为1.51,经过变量调整后依然有统计学意义。共137例SSI患者及相匹配的255例对照患者进行第二项研究,评估手术当天吸烟的影响。手术当天吸烟与SSI的OR值为1.96,经过变量调整后仍然具有统计学意义。术前呼出一氧化碳水平与SSI发病率无关,表明手术当天吸烟与SSI之间的联系与术前一氧化碳水平无关。

文章最后认为,吸烟与SSI发病有关,手术当天吸烟与SSI发病独立相关。这些数据并不能区分是戒烟降低了风险还是与其他可能的协变量有关。

原始出处:

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  2. [GetPortalCommentsPageByObjectIdResponse(id=1632297, encodeId=4906163229e20, content=<a href='/topic/show?id=10e7562854e' target=_blank style='color:#2F92EE;'>#择期手术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=56285, encryptionId=10e7562854e, topicName=择期手术)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=7db421894590, createdName=longerg, createdTime=Thu Sep 21 20:29:00 CST 2017, time=2017-09-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=208732, encodeId=1c39208e32e7, content=学习了,长知识了, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=84e21956153, createdName=1e1263e3m20(暂无匿称), createdTime=Fri Jun 09 23:21:19 CST 2017, time=2017-06-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1370530, encodeId=32ed13e0530bf, content=<a href='/topic/show?id=00505450e5f' target=_blank style='color:#2F92EE;'>#手术部位感染#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=54507, encryptionId=00505450e5f, topicName=手术部位感染)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4cce318, createdName=wleon8895, createdTime=Wed May 24 23:29:00 CST 2017, time=2017-05-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=201613, encodeId=75052016139b, content=学习一下谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzaiabIFicf63hKvVMjL6aJlx4yX4UcXmzX9DyibCRcicq0QtCRWMaQKh8MYjE1D3EKUBopgiaGWYuqbeR/0, createdBy=0c2b1999806, createdName=三生有幸9135, createdTime=Tue May 23 09:26:19 CST 2017, time=2017-05-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=201606, encodeId=40882016067f, content=很好!不错的,学习了!谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NdqKgfW3nMpOkC3jXxiaW2po0PtglY5ZuVjERqKADW4HyMI8bcZXWlKgH7tEP9ULBoBzuQMibia4pr1s9rQPqLvqQJ/0, createdBy=e8c02060444, createdName=中医痴, createdTime=Tue May 23 09:22:48 CST 2017, time=2017-05-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=201595, encodeId=a8bd2015953f, content=吸烟有害健康,珍爱生命,远离香烟。, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20170701/IMG595791009FB761316.jpg, createdBy=abd01695121, createdName=吴教授, createdTime=Tue May 23 08:59:54 CST 2017, time=2017-05-23, status=1, ipAttribution=)]
    2017-06-09 1e1263e3m20(暂无匿称)

    学习了,长知识了

    0

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    2017-05-23 三生有幸9135

    学习一下谢谢分享

    0

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    2017-05-23 中医痴

    很好!不错的,学习了!谢谢分享!

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1632297, encodeId=4906163229e20, content=<a href='/topic/show?id=10e7562854e' target=_blank style='color:#2F92EE;'>#择期手术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=56285, encryptionId=10e7562854e, topicName=择期手术)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=7db421894590, createdName=longerg, createdTime=Thu Sep 21 20:29:00 CST 2017, time=2017-09-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=208732, encodeId=1c39208e32e7, content=学习了,长知识了, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=84e21956153, createdName=1e1263e3m20(暂无匿称), createdTime=Fri Jun 09 23:21:19 CST 2017, time=2017-06-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1370530, encodeId=32ed13e0530bf, content=<a href='/topic/show?id=00505450e5f' target=_blank style='color:#2F92EE;'>#手术部位感染#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=54507, encryptionId=00505450e5f, topicName=手术部位感染)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4cce318, createdName=wleon8895, createdTime=Wed May 24 23:29:00 CST 2017, time=2017-05-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=201613, encodeId=75052016139b, content=学习一下谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzaiabIFicf63hKvVMjL6aJlx4yX4UcXmzX9DyibCRcicq0QtCRWMaQKh8MYjE1D3EKUBopgiaGWYuqbeR/0, createdBy=0c2b1999806, createdName=三生有幸9135, createdTime=Tue May 23 09:26:19 CST 2017, time=2017-05-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=201606, encodeId=40882016067f, content=很好!不错的,学习了!谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NdqKgfW3nMpOkC3jXxiaW2po0PtglY5ZuVjERqKADW4HyMI8bcZXWlKgH7tEP9ULBoBzuQMibia4pr1s9rQPqLvqQJ/0, createdBy=e8c02060444, createdName=中医痴, createdTime=Tue May 23 09:22:48 CST 2017, time=2017-05-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=201595, encodeId=a8bd2015953f, content=吸烟有害健康,珍爱生命,远离香烟。, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20170701/IMG595791009FB761316.jpg, createdBy=abd01695121, createdName=吴教授, createdTime=Tue May 23 08:59:54 CST 2017, time=2017-05-23, status=1, ipAttribution=)]
    2017-05-23 吴教授

    吸烟有害健康,珍爱生命,远离香烟。

    0

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