Clin Sci:三手烟的危害

2017-09-16 Darren 来宝网

加利福尼亚大学河滨分校的研究人员发现,接触三手烟(THS)即便一个月后对人们的健康仍有有重要影响,并且随着时间的推移,这种影响越来越严重。



[三手烟的危害你知道吗]加利福尼亚大学河滨分校的研究人员发现,接触三手烟(THS)即便一个月后对人们的健康仍有有重要影响,并且随着时间的推移,这种影响越来越严重。

当燃烧的香烟尖端发出的烟雾附着在衣服,头发,家里和汽车等表面上时,即形成三手烟。三手烟已经在动物实验中观察到能够引起2型糖尿病,多动症,肝和肺损伤以及其他并发症。

研究人员对保留在三手烟环境中的生物分子标志物或血清中发现的“生物标志物”,以及三手烟对肝脏和脑组织的影响进行了研究。分子生物学教授Manuela Martins-Green说:“我们的目标是确定当暴露在三手烟环境中时,小鼠的生理变化情况。结果发现暴露在三手烟环境中的小鼠在第一个月就出现了肝损伤,暴露两个月后导致了进一步的细胞水平损伤,四至六个月后引起更多的损伤,我们还发现暴露在三手烟环境中的小鼠长时间显示胰岛素抵抗。”

三手烟对肝脏的伤害可能会阻碍其对体内毒素的解毒作用,导致毒素损伤更多。Martins-Green和她的团队检查了暴露在三手烟环境中的小鼠大脑,发现应激激素(如肾上腺素)在一个月的暴露中呈增加趋势。在两个月,四个月,六个月时间内出现额外的应激激素,最终导致小鼠出现免疫疲劳。

这项研究结果发表在波兰的医学期刊《临床科学》杂志上。

Martins-Green说:“三手烟是一种隐形毒素,一个无声的杀手。三手烟污染物可以通过皮肤和呼吸吸收,虽然我们的研究并不是针对人类进行的,但人们应该意识到吸烟者所在的酒店房间,车内或者家庭中很可能被三手烟污染。大多数人都不知道他们正在暴露于三手烟环境,或者不相信衣服上沾点烟味可以对我们的健康有伤害。不可见但可闻到的三手烟毒素保留在我们接触的物体表面多年,并且耐强力清洁剂。此外,它们通过与环境空气反应而积累和老化,并最终变成致癌化学物质。

由于三手烟容易被皮肤吸收,而儿童特别喜欢与家里的物品接触,因此显得特别脆弱。孩子们经常把手放在嘴里,不知不觉就会摄入这些毒素。儿童还可以通过皮肤来吸收它们。家长在家中吸烟的话,儿童在其尿液中可以检测出烟草代谢物,以及来源这些烟草的特异性亚硝胺的衍生致癌物质。

医学研究委员会免疫药理学临床教授Stephen T. Holgate说:“暴露在家庭和室内灰尘中沉积的烟草烟雾是一类全新认可的毒性物质。一旦沉积在烟草烟雾中的有毒化学物质变的毒性和致癌性更大,对我们所有人的健康,特别是我们的孩子来说,是非常重要的威胁。”加利福尼亚研究团队将进一步研究如何从家具及其他物体中除掉三手烟危害物的办法。

Martins-Green和她的团队将小鼠暴露于三手烟环境中长达6个月,在发现它们激素改变,胰岛素抵抗,代谢综合征等后1个月,2个月,4个月和6个月时收集大脑、肝脏和血清样本以供研究。实验时为了创造三手烟环境,研究人员将常见的家用织物如窗帘材料,室内装潢和地毯暴露在吸烟机上产生的二手烟以及香烟燃烧烟雾中,然后将这些材料放置在小鼠生活的笼中。研究人员随后以时间依赖的方式测试了小鼠暴露于三手烟环境与它们健康的关系,主要对小鼠肝脏和脑组织中9种生物标志物相关的15种标志物质进行了测定。

Martins-Green 说:“我们发现这些生物标志物与小鼠在三手烟中暴露时间呈时间依赖性显着相关。这些生物标志物一旦在人体中被验证,那么可以被用作暴露于THS的关键指标,以及预测这种暴露发生的时间。”

在其他初步实验中,Martins-Green和她的研究小组发现暴露于三手烟环境的小鼠比未暴露在此环境的小鼠社会性较差。由于三手烟带来的物质引起的胰岛素抵抗问题被视为与西方饮食相关。此外,研究人员发现,随着时间的推移,老鼠沉迷于三手烟环境。

显然,三手烟环境正在影响小鼠的行为。研究专家计划撰写关于三手烟对健康影响的综合报告。 不难想象,虽然科研工作是以研究小鼠为主要工作,但是可以推测出三手烟的巨大危害。成年人应避免在公共场合乃至家中吸烟,因为我们日常接触到物品所接触到这些烟雾后会产生大量有害物质,威胁我们自身以及后代的健康。

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    2017-09-17 ffffffffff

    谢谢分享谢谢分享

    0

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content=学习了.谢谢., beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/xkvRjYnJzzRJ2R0y7VhicibvkjPWHjIMmu4ZpKnE9cWAu4lVicS3uDUCfF4M4JWvrkrYfpb2KehPV0Ee29tPqyPEebBUibiaKhnvD/0, createdBy=f8412001184, createdName=惠映实验室, createdTime=Sat Sep 16 08:55:22 CST 2017, time=2017-09-16, status=1, ipAttribution=)]
    2017-09-17 1e1a50a1m36(暂无匿称)

    谢谢分享知识

    0

  4. 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encodeId=761624458655, content=三手烟.无形中的危害因子., beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=60791943465, createdName=1e0f8808m18(暂无匿称), createdTime=Sat Sep 16 09:55:38 CST 2017, time=2017-09-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=244576, encodeId=9e542445e623, content=阅读了.谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=16, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo5nmIH5IQqCKjJgSCuicPWUWOUcdqt1ROPnEiaOYN4pSHibDv8la3OxNLalvuvUXn8clpJlrpuyTpckgt9OPkeSSdT/0, createdBy=8fd71930726, createdName=半夏微凉, createdTime=Sat Sep 16 09:29:53 CST 2017, time=2017-09-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=244555, encodeId=2f9b24455564, content=学习了.谢谢., beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/xkvRjYnJzzRJ2R0y7VhicibvkjPWHjIMmu4ZpKnE9cWAu4lVicS3uDUCfF4M4JWvrkrYfpb2KehPV0Ee29tPqyPEebBUibiaKhnvD/0, createdBy=f8412001184, createdName=惠映实验室, createdTime=Sat Sep 16 08:55:22 CST 2017, time=2017-09-16, status=1, ipAttribution=)]
    2017-09-17 李东泽

    很好.学习了.很有帮助.

    0

  5. 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content=学习了.谢谢., beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/xkvRjYnJzzRJ2R0y7VhicibvkjPWHjIMmu4ZpKnE9cWAu4lVicS3uDUCfF4M4JWvrkrYfpb2KehPV0Ee29tPqyPEebBUibiaKhnvD/0, createdBy=f8412001184, createdName=惠映实验室, createdTime=Sat Sep 16 08:55:22 CST 2017, time=2017-09-16, status=1, ipAttribution=)]
    2017-09-16 尹玉伟

    厉害厉害--学习了--

    0

  6. 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replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRoMjVmFh7PMNtxpIv1A1s9EVvpF69WTWibNMGTTTozRQx7icIcicROpyS6OSKw9lHxDLFLOdfezCIibp/0, createdBy=fe331939879, createdName=1e0ebf30m03(暂无匿称), createdTime=Sat Sep 16 17:10:22 CST 2017, time=2017-09-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=244659, encodeId=bb3a2446591c, content=二手烟.三手烟.让那些不吸烟者同样处于危险因素之中.罪魁祸首还是吸烟者.害了自己.害了别人.还造成环境的不可逆损害., beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/08/04/0723196b0475bd13fcb558f0517dbad7.jpg, createdBy=44622104218, createdName=apan小潘潘, createdTime=Sat Sep 16 15:35:02 CST 2017, time=2017-09-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=244586, encodeId=761624458655, content=三手烟.无形中的危害因子., beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=60791943465, createdName=1e0f8808m18(暂无匿称), createdTime=Sat Sep 16 09:55:38 CST 2017, time=2017-09-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=244576, encodeId=9e542445e623, content=阅读了.谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=16, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo5nmIH5IQqCKjJgSCuicPWUWOUcdqt1ROPnEiaOYN4pSHibDv8la3OxNLalvuvUXn8clpJlrpuyTpckgt9OPkeSSdT/0, createdBy=8fd71930726, createdName=半夏微凉, createdTime=Sat Sep 16 09:29:53 CST 2017, time=2017-09-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=244555, encodeId=2f9b24455564, content=学习了.谢谢., beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/xkvRjYnJzzRJ2R0y7VhicibvkjPWHjIMmu4ZpKnE9cWAu4lVicS3uDUCfF4M4JWvrkrYfpb2KehPV0Ee29tPqyPEebBUibiaKhnvD/0, createdBy=f8412001184, createdName=惠映实验室, createdTime=Sat Sep 16 08:55:22 CST 2017, time=2017-09-16, status=1, ipAttribution=)]
    2017-09-16 1e0ebf30m03(暂无匿称)

    已阅读

    0

  7. 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content=学习了.谢谢., beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/xkvRjYnJzzRJ2R0y7VhicibvkjPWHjIMmu4ZpKnE9cWAu4lVicS3uDUCfF4M4JWvrkrYfpb2KehPV0Ee29tPqyPEebBUibiaKhnvD/0, createdBy=f8412001184, createdName=惠映实验室, createdTime=Sat Sep 16 08:55:22 CST 2017, time=2017-09-16, status=1, ipAttribution=)]
    2017-09-16 apan小潘潘

    二手烟.三手烟.让那些不吸烟者同样处于危险因素之中.罪魁祸首还是吸烟者.害了自己.害了别人.还造成环境的不可逆损害.

    0

  8. 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content=学习了.谢谢., beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/xkvRjYnJzzRJ2R0y7VhicibvkjPWHjIMmu4ZpKnE9cWAu4lVicS3uDUCfF4M4JWvrkrYfpb2KehPV0Ee29tPqyPEebBUibiaKhnvD/0, createdBy=f8412001184, createdName=惠映实验室, createdTime=Sat Sep 16 08:55:22 CST 2017, time=2017-09-16, status=1, ipAttribution=)]
    2017-09-16 1e0f8808m18(暂无匿称)

    三手烟.无形中的危害因子.

    0

  9. 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createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzUn81b5CF5ibVPib8jWI92iciaxmqGHlwruOnK4SVZykd4iahqo1hicklIibyZoxm55X7EM8BW9eX1h1hQ2/0, createdBy=8aa81937526, createdName=李东泽, createdTime=Sun Sep 17 00:23:01 CST 2017, time=2017-09-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=244744, encodeId=2314244e44db, content=厉害厉害--学习了--, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLCSvgHPvuQp0g9YLQuk8Dv2tO2J8cA1nBOPWOR46Rv1IMw309iaVI4zibSE52MibbXtA54h46besGYv6vpQfsUHpY9TaCKOVRmm2A/0, createdBy=14511949364, createdName=尹玉伟, createdTime=Sat Sep 16 22:28:54 CST 2017, time=2017-09-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=244672, encodeId=d72c2446e2a7, content=已阅读, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRoMjVmFh7PMNtxpIv1A1s9EVvpF69WTWibNMGTTTozRQx7icIcicROpyS6OSKw9lHxDLFLOdfezCIibp/0, createdBy=fe331939879, createdName=1e0ebf30m03(暂无匿称), createdTime=Sat Sep 16 17:10:22 CST 2017, time=2017-09-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=244659, encodeId=bb3a2446591c, content=二手烟.三手烟.让那些不吸烟者同样处于危险因素之中.罪魁祸首还是吸烟者.害了自己.害了别人.还造成环境的不可逆损害., beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/08/04/0723196b0475bd13fcb558f0517dbad7.jpg, createdBy=44622104218, createdName=apan小潘潘, createdTime=Sat Sep 16 15:35:02 CST 2017, time=2017-09-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=244586, encodeId=761624458655, content=三手烟.无形中的危害因子., beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=60791943465, createdName=1e0f8808m18(暂无匿称), createdTime=Sat Sep 16 09:55:38 CST 2017, time=2017-09-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=244576, encodeId=9e542445e623, content=阅读了.谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=16, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo5nmIH5IQqCKjJgSCuicPWUWOUcdqt1ROPnEiaOYN4pSHibDv8la3OxNLalvuvUXn8clpJlrpuyTpckgt9OPkeSSdT/0, createdBy=8fd71930726, createdName=半夏微凉, createdTime=Sat Sep 16 09:29:53 CST 2017, time=2017-09-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=244555, encodeId=2f9b24455564, content=学习了.谢谢., beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/xkvRjYnJzzRJ2R0y7VhicibvkjPWHjIMmu4ZpKnE9cWAu4lVicS3uDUCfF4M4JWvrkrYfpb2KehPV0Ee29tPqyPEebBUibiaKhnvD/0, createdBy=f8412001184, createdName=惠映实验室, createdTime=Sat Sep 16 08:55:22 CST 2017, time=2017-09-16, status=1, ipAttribution=)]
    2017-09-16 半夏微凉

    阅读了.谢谢分享

    0

  10. 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replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRoMjVmFh7PMNtxpIv1A1s9EVvpF69WTWibNMGTTTozRQx7icIcicROpyS6OSKw9lHxDLFLOdfezCIibp/0, createdBy=fe331939879, createdName=1e0ebf30m03(暂无匿称), createdTime=Sat Sep 16 17:10:22 CST 2017, time=2017-09-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=244659, encodeId=bb3a2446591c, content=二手烟.三手烟.让那些不吸烟者同样处于危险因素之中.罪魁祸首还是吸烟者.害了自己.害了别人.还造成环境的不可逆损害., beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/08/04/0723196b0475bd13fcb558f0517dbad7.jpg, createdBy=44622104218, createdName=apan小潘潘, createdTime=Sat Sep 16 15:35:02 CST 2017, time=2017-09-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=244586, 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content=学习了.谢谢., beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/xkvRjYnJzzRJ2R0y7VhicibvkjPWHjIMmu4ZpKnE9cWAu4lVicS3uDUCfF4M4JWvrkrYfpb2KehPV0Ee29tPqyPEebBUibiaKhnvD/0, createdBy=f8412001184, createdName=惠映实验室, createdTime=Sat Sep 16 08:55:22 CST 2017, time=2017-09-16, status=1, ipAttribution=)]
    2017-09-16 惠映实验室

    学习了.谢谢.

    0

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