Stroke:如何快速识别前循环颅内大血管闭塞的缺血性卒中患者?

2017-03-15 CSA&TISC 天坛会

来自德国柏林卒中研究中心Scheitz JF等开展的一项前瞻性研究表明,通过简单改良的面-臂-语言-时间评分或评估NIHSS的症状表现可能有助于对前循环颅内大血管闭塞(LAVO)患者进行危险分层,并快速识别需要转移到综合卒中中心的患者。院前进行前瞻性测评是很有必要的。该项研究发表在Stroke杂志上。美国国立卫生研究院卒中量表(NIHSS)与前循环颅内大血管闭塞(LAVO)密切相关。因此,NIHS



来自德国柏林卒中研究中心Scheitz JF等开展的一项前瞻性研究表明,通过简单改良的面-臂-语言-时间评分或评估NIHSS的症状表现可能有助于对前循环颅内大血管闭塞(LAVO)患者进行危险分层,并快速识别需要转移到综合卒中中心的患者。院前进行前瞻性测评是很有必要的。该项研究发表在Stroke杂志上。

美国国立卫生研究院卒中量表(NIHSS)与前循环颅内大血管闭塞(LAVO)密切相关。因此,NIHSS常被推荐用于评估患者是否需要血管内治疗。然而,在院前准备中根据完整的NIHSS来选择符合血栓切除术治疗患者是有限的。因此,本研究旨在评估简化临床策略的预后价值。

研究纳入SITS-ISTR(2012年1月-2014年5月)中NIHSS评分完全分解并记录血管状态的3505例患者进行回顾性分析。研究员评估了LAVO(颈内动脉、颈动脉末端或大脑中动脉M1段)院前卒中量表和NIHSS症状谱的相关性。

研究显示23.6%的患者(n=827)患有LAVO,基线NIHSS与LAVO密切相关(调整OR,1.15;95%CI,1.13-1.16),病理学发现NIHSS中凝视项目与LAVO强烈相关(调整OR,4.5;95%CI,3.8-5.3)。所有3项面-臂-语言-时间测试(FAST)能高灵敏识别LAVO(OR,7.9;95%CI,5.2-11.9)。与原始FAST量表相比,将凝视项目添加到原始FAST评分(G-FAST)或其他简化的高分数卒中量表上的特异性上升(P<0.001)。代表全部前循环特征的NIHSS与非特异性临床图谱相比,LAVO的可能性增加了10倍。与NIHSS评分≥6(AUC,0.60;95%CI,0.58-0.62)相比,院前卒中量表G-FAST≥3(AUC,0.64;95%CI,0.62-0.66)和C-STAT≥1(AUC,0.63;95%CI,0.61-0.65)的表现相近或更好(P<0.001),并且不会损失灵敏度(89%-91%)。

该研究表明简单改良的面-臂-语言-时间评分或评估NIHSS症状表现可能有助于对LAVO患者危险分层并快速识别需要转移到综合卒中中心的患者。院前进行前瞻性测评是很有必要的。

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  5. [GetPortalCommentsPageByObjectIdResponse(id=1892839, encodeId=d0f4189283941, content=<a href='/topic/show?id=c738e93521f' target=_blank style='color:#2F92EE;'>#缺血性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79352, encryptionId=c738e93521f, topicName=缺血性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=66ec123, createdName=guihongzh, createdTime=Mon Feb 12 14:51:00 CST 2018, time=2018-02-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2010360, encodeId=4d2820103600c, content=<a href='/topic/show?id=9cf7e9360d2' target=_blank style='color:#2F92EE;'>#缺血性卒中患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79360, encryptionId=9cf7e9360d2, topicName=缺血性卒中患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1072181, createdName=wjywjy, createdTime=Tue Sep 05 16:51:00 CST 2017, time=2017-09-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1806131, encodeId=9ada180613158, content=<a href='/topic/show?id=b649e9358fa' target=_blank style='color:#2F92EE;'>#缺血性卒#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79358, encryptionId=b649e9358fa, topicName=缺血性卒)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=636e2500187, createdName=12498da4m32(暂无昵称), createdTime=Fri Mar 17 02:51:00 CST 2017, time=2017-03-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2009834, encodeId=c3e22009834dd, content=<a href='/topic/show?id=467789803a9' target=_blank style='color:#2F92EE;'>#血管闭塞#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89803, encryptionId=467789803a9, topicName=血管闭塞)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=827b160, createdName=cnxcy, createdTime=Sat May 06 23:51:00 CST 2017, time=2017-05-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1720155, encodeId=bd341e2015584, content=<a href='/topic/show?id=915c3604e6b' target=_blank style='color:#2F92EE;'>#卒中患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=36047, encryptionId=915c3604e6b, topicName=卒中患者)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=940232842333, createdName=wangyang7969, createdTime=Tue May 16 06:51:00 CST 2017, time=2017-05-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1706108, encodeId=ee541e061081d, content=<a href='/topic/show?id=7f6443986ec' target=_blank style='color:#2F92EE;'>#大血管#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=43986, encryptionId=7f6443986ec, topicName=大血管)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=caff31165455, createdName=kkunny, createdTime=Sat Sep 09 02:51:00 CST 2017, time=2017-09-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=180285, encodeId=c67f180285ef, content=凝视项很有提示意义, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e4cd1660740, createdName=dachengl, createdTime=Thu Mar 16 09:11:19 CST 2017, time=2017-03-16, status=1, ipAttribution=)]
  6. [GetPortalCommentsPageByObjectIdResponse(id=1892839, encodeId=d0f4189283941, content=<a href='/topic/show?id=c738e93521f' target=_blank style='color:#2F92EE;'>#缺血性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79352, encryptionId=c738e93521f, topicName=缺血性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=66ec123, createdName=guihongzh, createdTime=Mon Feb 12 14:51:00 CST 2018, time=2018-02-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2010360, encodeId=4d2820103600c, content=<a href='/topic/show?id=9cf7e9360d2' target=_blank style='color:#2F92EE;'>#缺血性卒中患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79360, encryptionId=9cf7e9360d2, topicName=缺血性卒中患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1072181, createdName=wjywjy, createdTime=Tue Sep 05 16:51:00 CST 2017, time=2017-09-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1806131, encodeId=9ada180613158, content=<a href='/topic/show?id=b649e9358fa' target=_blank style='color:#2F92EE;'>#缺血性卒#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79358, encryptionId=b649e9358fa, topicName=缺血性卒)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=636e2500187, createdName=12498da4m32(暂无昵称), createdTime=Fri Mar 17 02:51:00 CST 2017, time=2017-03-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2009834, encodeId=c3e22009834dd, content=<a href='/topic/show?id=467789803a9' target=_blank style='color:#2F92EE;'>#血管闭塞#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89803, encryptionId=467789803a9, topicName=血管闭塞)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=827b160, createdName=cnxcy, createdTime=Sat May 06 23:51:00 CST 2017, time=2017-05-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1720155, encodeId=bd341e2015584, content=<a href='/topic/show?id=915c3604e6b' target=_blank style='color:#2F92EE;'>#卒中患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=36047, encryptionId=915c3604e6b, topicName=卒中患者)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=940232842333, createdName=wangyang7969, createdTime=Tue May 16 06:51:00 CST 2017, time=2017-05-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1706108, encodeId=ee541e061081d, content=<a href='/topic/show?id=7f6443986ec' target=_blank style='color:#2F92EE;'>#大血管#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=43986, encryptionId=7f6443986ec, topicName=大血管)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=caff31165455, createdName=kkunny, createdTime=Sat Sep 09 02:51:00 CST 2017, time=2017-09-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=180285, encodeId=c67f180285ef, content=凝视项很有提示意义, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e4cd1660740, createdName=dachengl, createdTime=Thu Mar 16 09:11:19 CST 2017, time=2017-03-16, status=1, ipAttribution=)]
    2017-09-09 kkunny
  7. [GetPortalCommentsPageByObjectIdResponse(id=1892839, encodeId=d0f4189283941, content=<a href='/topic/show?id=c738e93521f' target=_blank style='color:#2F92EE;'>#缺血性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79352, encryptionId=c738e93521f, topicName=缺血性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=66ec123, createdName=guihongzh, createdTime=Mon Feb 12 14:51:00 CST 2018, time=2018-02-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2010360, encodeId=4d2820103600c, content=<a href='/topic/show?id=9cf7e9360d2' target=_blank style='color:#2F92EE;'>#缺血性卒中患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79360, encryptionId=9cf7e9360d2, topicName=缺血性卒中患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1072181, createdName=wjywjy, createdTime=Tue Sep 05 16:51:00 CST 2017, time=2017-09-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1806131, encodeId=9ada180613158, content=<a href='/topic/show?id=b649e9358fa' target=_blank style='color:#2F92EE;'>#缺血性卒#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79358, encryptionId=b649e9358fa, topicName=缺血性卒)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=636e2500187, createdName=12498da4m32(暂无昵称), createdTime=Fri Mar 17 02:51:00 CST 2017, time=2017-03-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2009834, encodeId=c3e22009834dd, content=<a href='/topic/show?id=467789803a9' target=_blank style='color:#2F92EE;'>#血管闭塞#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89803, encryptionId=467789803a9, topicName=血管闭塞)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=827b160, createdName=cnxcy, createdTime=Sat May 06 23:51:00 CST 2017, time=2017-05-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1720155, encodeId=bd341e2015584, content=<a href='/topic/show?id=915c3604e6b' target=_blank style='color:#2F92EE;'>#卒中患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=36047, encryptionId=915c3604e6b, topicName=卒中患者)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=940232842333, createdName=wangyang7969, createdTime=Tue May 16 06:51:00 CST 2017, time=2017-05-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1706108, encodeId=ee541e061081d, content=<a href='/topic/show?id=7f6443986ec' target=_blank style='color:#2F92EE;'>#大血管#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=43986, encryptionId=7f6443986ec, topicName=大血管)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=caff31165455, createdName=kkunny, createdTime=Sat Sep 09 02:51:00 CST 2017, time=2017-09-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=180285, encodeId=c67f180285ef, content=凝视项很有提示意义, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e4cd1660740, createdName=dachengl, createdTime=Thu Mar 16 09:11:19 CST 2017, time=2017-03-16, status=1, ipAttribution=)]
    2017-03-16 dachengl

    凝视项很有提示意义

    0

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健康的北欧饮食可能被推荐用于卒中预防。

BMJ:偏头痛患者围手术期卒中风险增加

已知偏头痛是缺血性卒中的一个危险因素,尤其是有先兆偏头痛。每年有约6000万次手术,基线卒中风险为1/1,000,如果有先兆偏头痛可使这一风险增加近2倍,那么每年会有数以千计的相关卒中发生。研究者报告称,偏头痛患者手术后第一个月发生缺血性卒中的风险是无头痛患者的近两倍。来自麻省综合医院(MGH)的Matthias Eikermann及其同事在BMJ杂志上在线报告,有先兆偏头痛患者的这一风险更高,不