JACC:吸烟与戒烟时间与3种心血管疾病的相关性研究

2019-07-29 不详 MedSci原创

既往研究抽烟对心血管疾病的影响主要是基于对于冠心病和卒中的影响,本研究的目的旨在量化吸烟及戒烟与3种心血管结局(冠心病、卒中和外周动脉疾病)发生率的长期关联性。本研究纳入了ARIC临床研究中13355名45-64岁基线水平无冠心病、卒中和外周动脉疾病的参与者。经过平均26年时间的随访,共有492例外周动脉疾病事件发生,1798例冠心病事件发生和1106例卒中事件发生。吸烟与3种心血管疾病结局呈剂量

既往研究抽烟对心血管疾病的影响主要是基于对于冠心病和卒中的影响,本研究的目的旨在量化吸烟及戒烟与3种心血管结局(冠心病、卒中和外周动脉疾病)发生率的长期关联性。

本研究纳入了ARIC临床研究中13355名45-64岁基线水平无冠心病、卒中和外周动脉疾病的参与者。经过平均26年时间的随访,共有492例外周动脉疾病事件发生,1798例冠心病事件发生和1106例卒中事件发生。吸烟与3种心血管疾病结局呈剂量相关性,其中外周动脉疾病最强。戒烟时间越长,3种心血挂疾病发生风险越低,但是,戒烟后30年的外周动脉疾病和戒烟后20年的冠心病风险明显增高。

研究结果显示,吸烟与3种心血管疾病结局均呈明显相关性,其中外周动脉疾病最强。外周动脉疾病的吸烟风险和冠心病的吸烟风险分别持续了30年和20年。

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    2020-06-12 hbwxf
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