Invest Ophthalmol Vis Sci.:动脉供血与人视网膜、脉络膜和视神经结的相互联系!

2017-07-23 cuiguizhong MedSci原创

西澳大利亚大学眼科与视觉科学中心的Yu DY团队近日在Invest Ophthalmol Vis Sci.杂志上发表了他们的一项重要工作,发现在人眼中,动脉供血与视网膜、脉络膜和ONH之间存在相互联系。

西澳大利亚大学眼科与视觉科学中心的Yu DY团队近日在Invest Ophthalmol Vis Sci.杂志上发表了他们的一项重要工作,发现在人眼中,动脉供血与视网膜、脉络膜和ONH之间存在相互联系。

目前,普遍的观点认为,人视网膜由中央视网膜动脉(CRA)和后部短的睫状动脉(SPCAs)供养支持的脉络膜,并且CRA和SPCAs都是所谓的"末端动脉"系统。在这发表的研究中,他们使用选择性插管和微灌注标记技术,研究是否存在视网膜,脉络膜和视神经结(ONH)之间的血管连接。

具体研究方法如下,在18例志愿者的眼中,他们选择CRA和SPCAs进行插管。在同一只眼睛上,为了区分不同血管网络的供应来源,他们将不同激发波长的荧光探针对不同的动脉进行灌注。经过标记和固定后,采用共焦显微镜,将ONH区域纵向或横向进行光切片。视网膜,脉络膜和ONH均采用光切片的方法。

他们发现,CRA或SPCA单独灌注的探针,被发现标记在视网膜,脉络膜和ONH区域中的微血管上。通过SPCA进行灌注时,椎板和视神经干的血管被标记。通过CRA和SPCA进行灌注,发现在视网膜,脉络膜和ONH中的血管中存在双重标记。

因此,他们认为,在人眼中,动脉供血与视网膜,脉络膜和ONH之间存在相互联系。这项工作,对于深入了解临床症状和发病机制,如青光眼和缺血性视神经疾病等,具有重要意义。

原文出处:

Yu, P.K., et al., Inter-Relationship of Arterial Supply to Human Retina, Choroid, and Optic Nerve Head Using Micro Perfusion and Labeling. Invest Ophthalmol Vis Sci, 2017. 58(9): p. 3565-3574.

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    2017-07-25 zutt
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    2017-07-23 天涯183

    非常好的文章,学习了,很受益

    0

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    2017-07-23 1ddf0692m34(暂无匿称)

    学习了,好文章

    0

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    2017-07-23 明月清辉

    谢谢分享,学习了

    0

  9. [GetPortalCommentsPageByObjectIdResponse(id=1666944, encodeId=793b16669441a, content=<a href='/topic/show?id=5fda90e061e' target=_blank style='color:#2F92EE;'>#视神经#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=90706, encryptionId=5fda90e061e, topicName=视神经)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=14db26078051, createdName=gj0740, createdTime=Thu Jan 11 23:36:00 CST 2018, time=2018-01-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1686999, encodeId=e22716869993e, content=<a href='/topic/show?id=5f688449023' target=_blank style='color:#2F92EE;'>#脉络膜#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=84490, encryptionId=5f688449023, topicName=脉络膜)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a15828309522, createdName=12498568m59暂无昵称, createdTime=Sat Nov 04 01:36:00 CST 2017, time=2017-11-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2050786, encodeId=fc9d2050e86b1, content=<a href='/topic/show?id=95f8e042dd' target=_blank style='color:#2F92EE;'>#EST#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7042, encryptionId=95f8e042dd, topicName=EST)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e9a6357, createdName=xiangyuzhou971, createdTime=Mon Aug 14 02:36:00 CST 2017, time=2017-08-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1269915, encodeId=d9741269915df, content=<a href='/topic/show?id=979690e33bd' target=_blank style='color:#2F92EE;'>#视网膜#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=90733, encryptionId=979690e33bd, topicName=视网膜)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=742793, createdName=zutt, createdTime=Tue Jul 25 09:36:00 CST 2017, time=2017-07-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1541248, encodeId=c8b1154124856, content=<a href='/topic/show?id=5c961e37307' target=_blank style='color:#2F92EE;'>#THA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=17373, encryptionId=5c961e37307, topicName=THA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=615b13300589, createdName=1249842em13(暂无昵称), createdTime=Tue Jul 25 09:36:00 CST 2017, time=2017-07-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=225579, encodeId=79212255e95e, content=非常好的文章,学习了,很受益, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7LIiaRZTzJ3SEfiauCzTMPW7YvPPYLNJBXG9oh6Al1icq2VQQkIHWxqXehcicTS62YKJVBhxeth3wggw/0, createdBy=7ce01621306, createdName=天涯183, createdTime=Sun Jul 23 23:32:57 CST 2017, time=2017-07-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=225551, encodeId=fb00225551e6, content=学习了,好文章, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220115/46bcf39c32de4aa6b45c5f9d66c8ee77/6cb4a20c55bb4b7691122f47747bfca2.jpg, createdBy=9dad1662329, createdName=1ddf0692m34(暂无匿称), createdTime=Sun Jul 23 21:08:06 CST 2017, time=2017-07-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=225540, encodeId=1d52225540cf, content=谢谢分享,学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6Nx0VGA4QMDzOP8oAgnV4h51EjSfehJ9QxyiaSmw8PB56BhY8KXFSxHCibXrzcy4abrzSibXQPxJ9kzrLcJyhhB8a/0, createdBy=1d3b1672603, createdName=明月清辉, createdTime=Sun Jul 23 19:08:05 CST 2017, time=2017-07-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=225539, encodeId=1a7722553940, content=感谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/07/17/0ed05bbc4eb124766d2a39104932ec4e.jpg, createdBy=5afd2091871, createdName=情途末路, createdTime=Sun Jul 23 19:07:34 CST 2017, time=2017-07-23, status=1, ipAttribution=)]
    2017-07-23 情途末路

    感谢分享

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