Sci Rep:骨钙素在患有勃起功能障碍的中年男性中的潜在保护性作用研究

2018-05-09 AlexYang MedSci原创

与勃起功能障碍(ED)相似,骨钙素(OC)同样被认为与心血管疾病(CVD)相关;然而,OC在ED中的作用仍旧不清楚。最近,有研究人员基于2009年9月到12月之间的防城港地区的男性健康调查(FAMHES)计划数据进行了相关的研究。研究人员利用国际勃起功能指数(IIEF-5)评估了ED情况。研究发现,OC与轻度(未调整: OR=0.647; P=0.016)或者中度(未调整:OR=0.453; P=

与勃起功能障碍(ED)相似,骨钙素(OC)同样被认为与心血管疾病(CVD)相关;然而,OC在ED中的作用仍旧不清楚。

最近,有研究人员基于2009年9月到12月之间的防城港地区的男性健康调查(FAMHES)计划数据进行了相关的研究。研究人员利用国际勃起功能指数(IIEF-5)评估了ED情况。研究发现,OC与轻度(未调整: OR=0.647; P=0.016)或者中度(未调整:OR=0.453; P=0.007)ED相关。同时,更高水平的OC与ED更加明显的相关(未调整: OR=0.702; P=0.014)。当研究人员将参与者按照年龄分组,OC与ED的相关性只在那些40-49岁之间的人群中出现,甚至在多重调整后模型且患有中度(OR=0.255, P=0.044)或者重度(OR=0.065, P=0.005)ED的患者中同样有上述现象。另外,OC与ED的关系同时也与高水平的睾丸素水平、非肥胖、饮酒和非代谢综合症相关。

最后,研究人员指出,OC也许在患有中度到重度ED的中年(40-49岁)男性中具有保护性作用,尤其是在那些具有高水平睾丸素、非肥胖、饮酒和非代谢综合症的男性中。

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    2018-12-10 habb
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    2018-05-10 1de11f7fm56(暂无匿称)

    学习了.谢谢分享

    0

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