Lancet Oncol:世界范围内青年肿瘤发病及死亡率调查

2018-01-05 马钊 “医海拾贝微转化”微信号

位于法国里昂的世界卫生组织国际癌症研究机构(IARC)的 Freddie Bray团队分析了2012年IARC收录的共计184个国家或地区的975,396例青年(20-39岁)新发肿瘤病例及358,392例肿瘤相关死亡病例情况,其结果发表在上2017年12月的《Lancet Oncology》。

位于法国里昂的世界卫生组织国际癌症研究机构(IARC)的 Freddie Bray团队分析了2012年IARC收录的共计184个国家或地区的975,396例青年(20-39岁)新发肿瘤病例及358,392例肿瘤相关死亡病例情况,其结果发表在上2017年12月的《Lancet Oncology》。

此研究病例数据中共包含27种肿瘤类型,并使用年龄标准化的率(Age-standardizedRate,ASR)作为研究指标。每年全球发病ASR为43.3人/10万,肿瘤相关病死ASR为15.9人/10万。青年女性发病率是男性的2倍,肿瘤相关死亡率是男性的1.25倍。乳腺癌(8.4人/10万)、宫颈癌、甲状腺癌、白血病结直肠癌是发病率前几位的癌种,而肿瘤相关死亡率最高的为乳腺癌(2.1人/10万)、肝癌、白血病及宫颈癌。

青年肿瘤发病谱与儿童(包含青少年,0-19岁)及老年肿瘤发病谱不同,在0-19岁年龄段中常见的白血病及脑和中枢神经系统肿瘤在青年中也常见,一些常见的上皮来源的肿瘤(例如乳腺癌、宫颈癌和结直肠癌)在青年中更多,但仍少于高年龄阶层。

Fidler等人同时分析了地区及经济发展因素在癌症谱中的影响。感染相关肿瘤在发展水平低地区所占比例更大,大约有33.2%的肿瘤与感染因素有关,而在经济水平高的地区,感染相关肿瘤发病仅占11.3%。另外,相关数据显示,在经济水平高的地区,肿瘤发病率要高于经济水平低的地区(ASR64.5 VS 46.2),但是肿瘤相关死亡率却3倍低于经济水平低的地区(ASR 25.4 VS9.2)。

总之,全球青年人(20-39岁)的肿瘤谱与更年轻和更老人群的肿瘤谱均不同,与具体年龄段、性别、经济发展水平和地域有关。在经济水平低的地区,肿瘤的预防与治疗应进一步加强以降低死亡率。

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    2018-10-30 howi
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    2018-11-23 minlingfeng
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    2018-01-21 天地飞扬

    了解了.谢谢分享!

    0

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    2018-01-09 1209e435m98(暂无昵称)

    学习了.谢谢分享

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=1829411, encodeId=7190182941187, content=<a href='/topic/show?id=1b6210686b2' target=_blank style='color:#2F92EE;'>#Lancet#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10686, encryptionId=1b6210686b2, topicName=Lancet)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3f0227, createdName=howi, createdTime=Tue Oct 30 10:31:00 CST 2018, time=2018-10-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1865261, encodeId=a50f18652615e, content=<a href='/topic/show?id=16ce133504e' target=_blank style='color:#2F92EE;'>#Oncol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13350, encryptionId=16ce133504e, topicName=Oncol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b63894, createdName=minlingfeng, createdTime=Fri Nov 23 19:31:00 CST 2018, time=2018-11-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=280759, encodeId=7da7280e5989, content=了解了.谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/12/23/2f51002e1349ccda5be11c1eea1e1e60.jpg, createdBy=a22097948, createdName=天地飞扬, createdTime=Sun Jan 21 20:13:09 CST 2018, time=2018-01-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=276774, encodeId=17992e6774c4, content=学习了.谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7c592194322, createdName=1209e435m98(暂无昵称), createdTime=Tue Jan 09 06:49:53 CST 2018, time=2018-01-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=276542, encodeId=f0c32e654223, content=世界范围内青年肿瘤发病及死亡率调查., beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Mon Jan 08 07:23:29 CST 2018, time=2018-01-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=276291, encodeId=e32a2e62917f, content=学习了.涨知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220115/46bcf39c32de4aa6b45c5f9d66c8ee77/6cb4a20c55bb4b7691122f47747bfca2.jpg, createdBy=9dad1662329, createdName=1ddf0692m34(暂无匿称), createdTime=Sun Jan 07 09:08:09 CST 2018, time=2018-01-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=276053, encodeId=4e222e605372, content=^_^^_^^_^^_^, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/Swp2ehfHpiciczeTntUyQOlIGMzQ705ic67sdMTVMbwTv7KbmlUvxrGvRSvQZjPkz7ib5tEDfIaORgczPtmHDpwojg/0, createdBy=c54b2163125, createdName=wqkm, createdTime=Sat Jan 06 16:41:24 CST 2018, time=2018-01-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=275855, encodeId=4e422e585583, content=厉害了我的哥, beContent=null, objectType=article, channel=null, level=null, likeNumber=18, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib3IzoRn621JdKCFUI4XvNELcibocrAVU6aUzEVDSaf3rYH08PUYUiagGqxAEhj8g9WqqNvD1CupIpCrmnR2OrqHZh/0, createdBy=7f181365728, createdName=飛歌, createdTime=Sat Jan 06 00:07:54 CST 2018, time=2018-01-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=275821, encodeId=26822e5821aa, content=赞, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/PiajxSqBRaEL1lbeB4KXPkoejHWBRHudEaddxiaBQDGcgEsNibh974wniaAEJAYLAC6fddUD5MmvECdAOmMjNWbPibg/132, createdBy=57332207937, createdName=Fiona_rj, createdTime=Fri Jan 05 22:44:31 CST 2018, time=2018-01-05, status=1, ipAttribution=)]
    2018-01-08 jyzxjiangqin

    世界范围内青年肿瘤发病及死亡率调查.

    0

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    2018-01-07 1ddf0692m34(暂无匿称)

    学习了.涨知识

    0

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    2018-01-06 wqkm

    ^_^^_^^_^^_^

    0

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    2018-01-06 飛歌

    厉害了我的哥

    0

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    2018-01-05 Fiona_rj

    0

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