Radiology:预测心血管事件:左室肥厚优于冠状动脉钙化评分

2019-08-30 XUJING 中国循环杂志

根据发表在《Radiology》杂志上的一项新研究,左心室质量升高,即左心室肥大,比冠状动脉钙化评分更能预测不良心血管事件。

根据发表在《Radiology》杂志上的一项新研究,左心室质量升高,即左心室肥大,比冠状动脉钙化评分更能预测不良心血管事件。

研究使用了核磁共振(MRI),这是量化左心室质量的金标准。

多民族动脉粥样硬化研究(MESA)中,2000年至2002年间, 4988名受试者接受了基线心脏MRI检查,均接受了长达15年的随访。所有参与者在基线时的平均年龄是62岁,基线无心血管疾病

在15年的随访中,290例患者发生了严重冠心病事件,包括207例心肌梗死或心脏病发作,95例冠心病死亡。57例患者发生心血管疾病相关死亡,215例患者发生心力衰竭。

进一步分析表明,对于冠心病死亡、其他心血管死亡和心衰,左心室肥大是比冠状动脉钙化更强的预测因子。

根据分析,患有左心室肥大受试者中,有22%发生了不良心血管事件,没有左心室肥大的受试者中,仅有6%发生了不良心血管事件。

与无左室肥大的受试者相比,左室肥大患者的冠状动脉疾病相关死亡风险增加3.3倍。

Kaplan-Meier分析显示,左心室肥大5年后不良心血管事件风险开始增加。

原始出处:Kawel-Boehm N1, Kronmal R1, Eng J1, et al. Left Ventricular Mass at MRI and Long-Term Risk of Cardiovascular Events: The Multi-Ethnic Study of Atherosclerosis (MESA). Radiology. 2019 Aug 27

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    2019-08-31 130****4638

    学习了,谢谢分享

    0

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    2019-08-30 飛歌

    学习了很有用不錯

    0

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