PLoS One:卒中后吞咽困难发生的现状及对临床预后的影响

2016-03-14 MedSci MedSci原创

背景:文献中有关卒中后吞咽障碍的频率不一致。随着卒中管理的进展,研究者旨在评估急性缺血性卒中患者吞咽困难的现状。方法:研究者研究了570名患者。应用Gugging吞咽扫描(GUSS)评估吞咽困难的发生。研究者调查了吞咽困难和肺炎,住院时间,出院目的地之间的关系,并且比较了吞咽困难患者和非吞咽困难患者3个月临床良好预后和死亡率之间的关系。结果:118/570例(20.7%)患者确诊为吞咽困难,60例

背景:文献中有关卒中后吞咽障碍的频率不一致。随着卒中管理的进展,研究者旨在评估急性缺血性卒中患者吞咽困难的现状。

方法:研究者研究了570名患者。应用Gugging吞咽扫描(GUSS)评估吞咽困难的发生。研究者调查了吞咽困难和肺炎,住院时间,出院目的地之间的关系,并且比较了吞咽困难患者和非吞咽困难患者3个月临床良好预后和死亡率之间的关系。

结果:118/570例(20.7%)患者确诊为吞咽困难,60例(50.9%)患者持续到出院。36(30.5%)例患者因为严重的吞咽困难需插鼻胃管。卒中的严重程度,而不是梗死部位与吞咽困难相关。与无吞咽困难者相比,吞咽障碍患者肺炎发生率较高(23.1%比1.1%,P<0.001),监测脑卒中单元停留时间较长(4.4±2.8 vs. 2.7±2.4天;P<0.001)和出院回家者较少(19.5% vs 63.7%,P = 0.001)。3个月,吞咽困难的患者良好预后者较少(35.7%比69.7%;P<0.001),住在家里患者较少(38.8%比76.5%;P<0.001),死亡患者较多(13.6%比1.6%;P<0.001)。多因素分析确定吞咽困难是3个月出院目的地的独立预测因子,而严重的吞咽困难,需要放置导管与死亡率较高密切相关。

结论:吞咽困难仍然影响相当一部分脑卒中患者,并可能对临床预后、死亡率和出院去处有很大的影响。


原文出处:

Arnold M, Liesirova K, et al. Dysphagia in Acute Stroke: Incidence, Burden and Impact on Clinical Outcome. PLoS One. 2016 Feb 10

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    2017-06-26 151****6665

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