J Thorac Cardiovasc Surg:房颤患者手术治疗的预后,男女有别吗?

2016-01-24 phylis 译 MedSci原创

背景:房颤患者(AF),药物治疗的预后存在性别差异。这篇研究评估,房颤患者进行手术治疗,预后是否存在性别差异。方法:2004年4月到2012年12月,共有936名房颤患者进行手术治疗。采用倾向评分匹配方法按照性别进行预后分析。结果:936例患者中,,571(61%)为男性;女性年龄较大(68.6±11.3岁vs 66.9±11.9岁),心衰发生较多(44% vs 37%;P = 024),二尖瓣手

背景:房颤患者(AF),药物治疗的预后存在性别差异。这篇研究评估了,房颤患者进行手术治疗的预后是否存在性别差异。

方法:2004年4月到2012年12月,共有936名房颤患者进行手术治疗。采用倾向评分匹配方法按照性别进行预后分析。

结果:936例患者中,571例(61%)为男性;女性年龄较大(68.6±11.3岁vs 66.9±11.9岁),心衰发生较多(44% vs 37%;P = 024),二尖瓣手术较多(72% vs 50%;P<001)及三尖瓣瓣膜手术(41% vs 18%;P<001)。男性患者进行冠状动脉搭桥术(19%比37%)和主动脉瓣膜手术(31%比38%)较多。女性后期卒中率较高(0.15 vs 0.07),导管消融术较少(6% vs 9.8%),再发AF的心脏复律较少(15.7% vs 19.2%)。倾向性评分配对后,女性后期卒中率较高(0.12 vs 0.04)。整体生存率(5年生存率:78.8%男性和81%女性),AF发生或抗心律失常药物(71.8%的男性和73.6%的女性)之间无性别差异。

结论:老年女性手术治疗房颤后,心衰发生较多。倾向得分匹配后,卒中发生,整体生存或手术成功间没有性别差异。

原文出处:

Shah SV, Kruse J, et al. Gender differences in outcomes after surgical ablation of atrial fibrillation. J Thorac Cardiovasc Surg. 2015 Sep 28.

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    2016-09-22 yyj062
  2. [GetPortalCommentsPageByObjectIdResponse(id=2056989, encodeId=80a82056989ca, content=<a href='/topic/show?id=a19b1e4042f' target=_blank style='color:#2F92EE;'>#THORAC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=17404, encryptionId=a19b1e4042f, topicName=THORAC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=052a130, createdName=yyj062, createdTime=Thu Sep 22 01:44:00 CST 2016, time=2016-09-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1938531, encodeId=465e1938531cc, content=<a href='/topic/show?id=1c292818fd' target=_blank style='color:#2F92EE;'>#ASC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2818, encryptionId=1c292818fd, topicName=ASC)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=74808, createdName=quxin068, createdTime=Sat Apr 23 13:44:00 CST 2016, time=2016-04-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=65516, encodeId=49706551685, content=值得学习。, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=cfb791835, createdName=CHBLY, createdTime=Wed Feb 24 23:52:00 CST 2016, time=2016-02-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=61033, encodeId=bff96103360, content=心血管研究中请大家一定要注意性别,在其中可能起,中了,因此我们在做心血管研究室,要特别注意,对于性别的亚组分析, beContent=null, objectType=article, channel=null, level=null, likeNumber=137, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c4a5105539, createdName=lovetcm, createdTime=Wed Jan 27 18:15:00 CST 2016, time=2016-01-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1290575, encodeId=c25912905e586, content=<a href='/topic/show?id=e86454454ea' target=_blank style='color:#2F92EE;'>#手术治疗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=54454, encryptionId=e86454454ea, topicName=手术治疗)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=920c231, createdName=lixiaol, createdTime=Tue Jan 26 06:44:00 CST 2016, time=2016-01-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1614291, encodeId=6b7e16142912a, content=<a href='/topic/show?id=64f95426122' target=_blank style='color:#2F92EE;'>#房颤患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=54261, encryptionId=64f95426122, topicName=房颤患者)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=937e19519012, createdName=hittouch, createdTime=Tue Jan 26 06:44:00 CST 2016, time=2016-01-26, status=1, ipAttribution=)]
    2016-04-23 quxin068
  3. [GetPortalCommentsPageByObjectIdResponse(id=2056989, encodeId=80a82056989ca, content=<a href='/topic/show?id=a19b1e4042f' target=_blank style='color:#2F92EE;'>#THORAC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=17404, encryptionId=a19b1e4042f, topicName=THORAC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=052a130, createdName=yyj062, createdTime=Thu Sep 22 01:44:00 CST 2016, time=2016-09-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1938531, encodeId=465e1938531cc, content=<a href='/topic/show?id=1c292818fd' target=_blank style='color:#2F92EE;'>#ASC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2818, encryptionId=1c292818fd, topicName=ASC)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=74808, createdName=quxin068, createdTime=Sat Apr 23 13:44:00 CST 2016, time=2016-04-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=65516, encodeId=49706551685, content=值得学习。, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=cfb791835, createdName=CHBLY, createdTime=Wed Feb 24 23:52:00 CST 2016, time=2016-02-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=61033, encodeId=bff96103360, content=心血管研究中请大家一定要注意性别,在其中可能起,中了,因此我们在做心血管研究室,要特别注意,对于性别的亚组分析, beContent=null, objectType=article, channel=null, level=null, likeNumber=137, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c4a5105539, createdName=lovetcm, createdTime=Wed Jan 27 18:15:00 CST 2016, time=2016-01-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1290575, encodeId=c25912905e586, content=<a href='/topic/show?id=e86454454ea' target=_blank style='color:#2F92EE;'>#手术治疗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=54454, encryptionId=e86454454ea, topicName=手术治疗)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=920c231, createdName=lixiaol, createdTime=Tue Jan 26 06:44:00 CST 2016, time=2016-01-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1614291, encodeId=6b7e16142912a, content=<a href='/topic/show?id=64f95426122' target=_blank style='color:#2F92EE;'>#房颤患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=54261, encryptionId=64f95426122, topicName=房颤患者)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=937e19519012, createdName=hittouch, createdTime=Tue Jan 26 06:44:00 CST 2016, time=2016-01-26, status=1, ipAttribution=)]
    2016-02-24 CHBLY

    值得学习。

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=2056989, encodeId=80a82056989ca, content=<a href='/topic/show?id=a19b1e4042f' target=_blank style='color:#2F92EE;'>#THORAC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=17404, encryptionId=a19b1e4042f, topicName=THORAC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=052a130, createdName=yyj062, createdTime=Thu Sep 22 01:44:00 CST 2016, time=2016-09-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1938531, encodeId=465e1938531cc, content=<a href='/topic/show?id=1c292818fd' target=_blank style='color:#2F92EE;'>#ASC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2818, encryptionId=1c292818fd, topicName=ASC)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=74808, createdName=quxin068, createdTime=Sat Apr 23 13:44:00 CST 2016, time=2016-04-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=65516, encodeId=49706551685, content=值得学习。, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=cfb791835, createdName=CHBLY, createdTime=Wed Feb 24 23:52:00 CST 2016, time=2016-02-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=61033, encodeId=bff96103360, content=心血管研究中请大家一定要注意性别,在其中可能起,中了,因此我们在做心血管研究室,要特别注意,对于性别的亚组分析, beContent=null, objectType=article, channel=null, level=null, likeNumber=137, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c4a5105539, createdName=lovetcm, createdTime=Wed Jan 27 18:15:00 CST 2016, time=2016-01-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1290575, encodeId=c25912905e586, content=<a href='/topic/show?id=e86454454ea' target=_blank style='color:#2F92EE;'>#手术治疗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=54454, encryptionId=e86454454ea, topicName=手术治疗)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=920c231, createdName=lixiaol, createdTime=Tue Jan 26 06:44:00 CST 2016, time=2016-01-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1614291, encodeId=6b7e16142912a, content=<a href='/topic/show?id=64f95426122' target=_blank style='color:#2F92EE;'>#房颤患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=54261, encryptionId=64f95426122, topicName=房颤患者)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=937e19519012, createdName=hittouch, createdTime=Tue Jan 26 06:44:00 CST 2016, time=2016-01-26, status=1, ipAttribution=)]
    2016-01-27 lovetcm

    心血管研究中请大家一定要注意性别,在其中可能起,中了,因此我们在做心血管研究室,要特别注意,对于性别的亚组分析

    0

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