JAHA:年轻女性血红蛋白浓度变化与心血管风险和全因死亡率的关系

2018-08-16 xing.T MedSci原创

由此可见,这些研究结果表明定期进行Hb检查可能有助于识别有AMI、卒中、脑血管疾病和全因死亡风险的年轻女性。

贫血被认为会增加高危人群的死亡风险,但其影响尚未在年轻人群中进行检验。近日,血管疾病领域权威杂志JAHA上发表了一篇研究文章,该研究旨在确定血红蛋白(Hb)浓度及其变化对年轻女性急性心肌梗死(AMI)、卒中、脑血管疾病和全因死亡风险的影响。

研究人员分析了韩国国家健康信息数据库中808143名年龄在20至39岁但没有任何心脑血管疾病女性的数据。2年内Hb浓度增加一倍和Hb的变化作为研究暴露量。参与者的中位随访时间为10年,以确定AMI、卒中、脑血管疾病和全因死亡的风险。

通过分析,研究人员发现Hb浓度或Hb变化与AMI、卒中、脑血管疾病和全因死亡之间存在U形或J形关联。将Hb浓度从正常浓度增加至高浓度会增加了AMI的风险(风险比[95%置信区间]为1.49 [1.08-2.04])。对于卒中风险,将Hb浓度从正常浓度增加到高浓度会增加卒中的风险(风险比[95%置信区间]为1.10 [1.02-1.35]),并将Hb浓度从高浓度降低到正常范围会降低卒中的风险(风险比[95%置信区间]为0.80 [0.60-0.97])。将贫血症状改善,使Hb恢复至正常范围可降低全因死亡率(风险比[95%置信区间]为0.81 [0.69-0.94]); 然而,Hb浓度过度校正(Hb≥14.0g/dL)并不能显著降低全因死亡率。

由此可见,这些研究结果表明定期进行Hb检查可能有助于识别有AMI、卒中、脑血管疾病和全因死亡风险的年轻女性。

原始出处:


Gyeongsil Lee.et al. Association Between Changes in Hemoglobin Concentration and Cardiovascular Risks and All‐Cause Mortality Among Young Women.JAHA.2018. https://www.ahajournals.org/doi/full/10.1161/JAHA.117.008147

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    2018-10-07 秀红

    学习了

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    2018-08-18 zhaohui6731
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  6. [GetPortalCommentsPageByObjectIdResponse(id=2082469, encodeId=1559208246905, content=<a href='/topic/show?id=56658981223' target=_blank style='color:#2F92EE;'>#血管风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89812, encryptionId=56658981223, topicName=血管风险)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdqq.qlogo.cn/qqapp/101296147/78FA0899509C358B01B975E8EAC1F88A/100, createdBy=7d822500145, createdName=ms5353107019656438, createdTime=Wed Dec 19 20:39:00 CST 2018, time=2018-12-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=348268, encodeId=5f4e34826874, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2018/01/15/8213228fe923915543544ad3da7e1c64.jpg, createdBy=6bd82014262, createdName=秀红, createdTime=Sun Oct 07 04:33:58 CST 2018, time=2018-10-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1251500, encodeId=c26d12515002a, content=<a href='/topic/show?id=874529332ba' target=_blank style='color:#2F92EE;'>#全因死亡率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=29332, encryptionId=874529332ba, topicName=全因死亡率)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=796422, createdName=lvliquan, createdTime=Sat Aug 18 11:39:00 CST 2018, time=2018-08-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1267892, encodeId=474e126e892a6, content=<a href='/topic/show?id=922f21183d' target=_blank style='color:#2F92EE;'>#AHA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2118, encryptionId=922f21183d, topicName=AHA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bf3d82, createdName=zhaohui6731, createdTime=Sat Aug 18 11:39:00 CST 2018, time=2018-08-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1514987, encodeId=5139151498ee4, content=<a href='/topic/show?id=b593489e75b' target=_blank style='color:#2F92EE;'>#年轻女性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=48977, encryptionId=b593489e75b, topicName=年轻女性)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a0b410702302, createdName=thinkibmz_44722597, createdTime=Sat Aug 18 11:39:00 CST 2018, time=2018-08-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1544540, encodeId=ffde1544540c7, content=<a href='/topic/show?id=ac3d6549e75' target=_blank style='color:#2F92EE;'>#浓度#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=65497, encryptionId=ac3d6549e75, topicName=浓度)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=16b213663040, createdName=12498974m55暂无昵称, createdTime=Sat Aug 18 11:39:00 CST 2018, time=2018-08-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=339131, encodeId=7af733913120, content=学习!, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9b2e1935437, createdName=AlexYang, createdTime=Fri Aug 17 10:56:28 CST 2018, time=2018-08-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=339017, encodeId=a36a33901e71, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=82311653708, createdName=医者仁心5538, createdTime=Thu Aug 16 20:56:54 CST 2018, time=2018-08-16, status=1, ipAttribution=)]
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    2018-08-17 AlexYang

    学习!

    0

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    2018-08-16 医者仁心5538

    学习了

    0

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