JAHA:急性A型主动脉夹层再次手术后的结局

2017-10-26 xiangting MedSci原创

急性A型主动脉夹层修复后的再次手术与死亡率和发病率较低相关。

治疗急性A型主动脉夹层的最佳手术方法仍存在争议。这项研究旨在评估急性A型夹层修复后再次手术的结局,为指导手术提供决策。

对2005年8月至2016年4月单个转诊机构中的急性A型夹层修复术后的所有主动脉再次手术(n=129)进行了回顾。主要结局是30天或院内死亡率。次要结局包括器官特异性发病率和使用Kaplan-Meier方法估计的1年和5年结局。大多数的再手术是近端主动脉(主动脉瓣,主动脉根部或升部)或主动脉弓手术(62.5%,n = 55); 大多数的再次手术是择期进行的(83.1%,n = 74)。21例患者(23.6%)在初次再次手术后2.5年的中位随访期间,需要进行额外的第二次或更多次的再手术。再次手术的30天或院内死亡率为7.0%(择期:6.3%;非择期:11.1%)。考虑到手术的复杂性,器官特异性发病率在可接受范围内。初次再手术后1年和5年总生存率分别为85.9%和64.9%,5年时主动脉特异性生存率为88%。

急性A型主动脉夹层修复后的再次手术与死亡率和发病率较低相关。这些数据支持对急性A型夹层进行更局限的指标修复,特别是对在低容量没有广泛修复经验的医疗中心进行指标修复的患者,因为如果需要,可以在转诊至主动脉病中心安全进行再次手术。

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