Chest:急性呼吸衰竭间质性肺疾病危重成年人的预后及死亡预测模型!

2018-01-16 xing.T MedSci原创

由此可见,研究人员创建了一个风险评分,将急性呼吸衰竭的ILD患者的院内死亡风险从低到高进行分类。该评分可以为这些患者及其家属提供咨询。

近日,呼吸领域权威杂志chest上发表了一篇研究文章,研究人员旨在评估急性呼吸衰竭的间质性肺疾病(ILD)患者的短期和长期死亡率,并确定住院死亡风险较低或较高的患者。

研究人员对126名连续就诊的成年ILD患者进行了一项回顾性队列研究,这些住院期间未接受肺移植的患者在2010至2014年间因呼吸衰竭入住三级医疗机构的重症监护病房(ICU)。研究人员使用泊松回归评估了入住ICU第1天时的特征与院内和1年死亡率之间的相关性,并使用Kaplan Meier曲线评估了生存期。研究人员使用惩罚性回归模型创建了院内死亡风险评分。

院内死亡率为66%,1年死亡率为80%。那些与ILD相关的结缔组织病患者与不可分类的ILD患者相比,具有更低的短期和长期死亡率(校正RR分别为0.6,95%可信区间为0.3-0.9和RR为0.6,95%可信区间为0.4-0.9)。研究人员创建的预测模型包括男性、间质性肺纤维化诊断、有创机械通气和/或体外生命支持的使用、入住ICU24小时内未移动、体重指数和简化的急性生理评分-II。乐观校正的c统计量为0.73,并且模型校准较优越(P=0.99)。低、中,高危人群的院内死亡率分别为33%、65%和96%。

由此可见,研究人员创建了一个风险评分,将急性呼吸衰竭的ILD患者的院内死亡风险从低到高进行分类。该评分可以为这些患者及其家属提供咨询。

原始出处:

Whitney Gannon,et al.Outcomes and mortality prediction model of critically ill adults with acute respiratory failure and interstitial lung disease.chest.2018.http://dx.doi.org/10.1016/j.chest.2018.01.006

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    2018-10-31 Smile2680
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    2018-01-16 thlabcde

    好资料学习了!

    0

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    2018-01-16 红木中餐

    henhao

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    2018-01-16 131****1460

    学习了受益匪浅

    0

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