J Glaucoma. :饮水测试的眼内压峰值可以预测青光眼视觉发展情况!

2017-07-24 cuiguizhong MedSci原创

哥伦比亚大学医学中心眼科的De Moraes CG在J Glaucoma.发表了一项工作,他们这项工作的目的是测试他们提出的一个假设:在压力测试时[饮水测试(WDT)],眼内压(IOP)峰值可以用来预测经过治疗的原发性开角型青光眼(POAG)患者未来视野恢复过程中的风险。

哥伦比亚大学医学中心眼科的De Moraes CG在J Glaucoma.发表了一项工作,他们这项工作的目的是测试他们提出的一个假设:在压力测试时[饮水测试(WDT)],眼内压(IOP)峰值可以用来预测经过治疗的原发性开角型青光眼(POAG)患者未来视野恢复过程中的风险。

他们采用前瞻性、纵向研究的方法,设置临床实践,对经过治疗的POAG患者进行研究,这项患者都是眼压低于18毫米汞柱,在WDT测试和符合条件的视野最近的日期之间没有进行过IOP降低干预的。在基准检查时,患者进行WDT测试,然后按照标准的IOP测量和视野测试进行定期的跟踪。他们主要观察指标是,危险生存分析测试的比值,即WDT测试时IOP峰值的预测值/视觉恢复期间工作时间时IOP测量值的比值,

他们分析了96例视野损伤患者的144例眼睛,从轻度至重度,平均跟踪研究时间为28个月。排除潜在的混杂因素,在多变量分析中他们发现,WDT测试时IOP峰值更好的预测了未来视野发展情况(风险比= 1.11; 95%置信区间,1.02至1.21; P = 0.013)。在同一随访时间,IOP工作时间内平均值和峰值与视觉进展无显着相关性(P = 0.651和0.569)。

因此,他们认为,用WDT测试的眼内压(IOP)峰值可以很好的预测经治疗的原发性开角型青光眼(POAG)群体未来视觉的进展。这种压力测试有可能成为日常实践中风险评估的有力工具。

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    2018-06-06 aliceclz
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    2017-07-26 zywlvao
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    2017-07-25 changjiu

    学习了,谢谢

    0

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    2017-07-24 189****7206

    学习了谢谢分享

    0

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    2017-07-24 131****1460

    学习了受益匪浅。

    0

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