JACC:子代四种先心病发病率随着孕母BMI增高而增高

2019-01-10 MedSci MedSci原创

孕妇超重或者肥胖生患有先天性心脏病的子代概率更高,本研究的目的旨在评估孕妇超重或肥胖与复杂先心或各先心亚型发病风险的相关性。本研究纳入了瑞典国家数据库1992-2012年出生的2050491名婴儿,孕母根据BMI分为低体重组(BMI<18.5kg/m2)、正常体重组(BMI 18.5至<25kg/m2)、超重组(BMI 25至<30kg/m2)、一级肥胖组(BMI 30至<

孕妇超重或者肥胖生患有先天性心脏病的子代概率更高,本研究的目的旨在评估孕妇超重或肥胖与复杂先心或各先心亚型发病风险的相关性。

本研究纳入了瑞典国家数据库1992-2012年出生的2050491名婴儿,孕母根据BMI分为低体重组(BMI<18.5kg/m2)、正常体重组(BMI 18.5至<25kg/m2)、超重组(BMI 25至<30kg/m2)、一级肥胖组(BMI 30至<35kg/m2)、二级肥胖组(BMI 35至<40kg/m2)和三级肥胖组(BMI≥40kg/m2),临床结局包括复杂先心(法四、大动脉转位、主动脉弓异常和单心室)和一些具体的先心亚型。分析结果显示,有28628名(1.4%)儿童至少患有一种先心病,主动脉弓异常的发病率随着孕母肥胖程度增高而增加,与体重正常的孕母相比,严重肥胖孕母子代的主动脉弓异常和大动脉转位的发病率翻了一倍。另外,足月产婴儿的房间隔缺损和动脉导管未闭发病率随着孕母的BMI增加而增高。

研究结果显示,主动脉弓异常、大动脉转位、房间隔缺损和动脉导管未闭的发病率随着孕母的BMI增高而增高。

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    2019-10-06 楚钟
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    2019-08-30 hbwxf
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    2019-01-12 ssnine
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  6. [GetPortalCommentsPageByObjectIdResponse(id=1736264, encodeId=293a1e362640d, content=<a href='/topic/show?id=fd874512592' target=_blank style='color:#2F92EE;'>#子代#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=45125, encryptionId=fd874512592, topicName=子代)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e32134104358, createdName=楚钟, createdTime=Sun Oct 06 09:32:00 CST 2019, time=2019-10-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1823523, encodeId=93ec18235234c, content=<a href='/topic/show?id=b2873e9220e' target=_blank style='color:#2F92EE;'>#发病率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37922, encryptionId=b2873e9220e, topicName=发病率)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=aa0e14, createdName=lifestar, createdTime=Mon Jul 01 22:32:00 CST 2019, time=2019-07-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1854282, encodeId=3b471854282b7, content=<a href='/topic/show?id=48351020537' target=_blank style='color:#2F92EE;'>#JACC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10205, encryptionId=48351020537, topicName=JACC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=55ce62, createdName=hbwxf, createdTime=Fri Aug 30 06:32:00 CST 2019, time=2019-08-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1311487, encodeId=e051131148e3e, content=<a href='/topic/show?id=a12628e0852' target=_blank style='color:#2F92EE;'>#先心病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=28708, encryptionId=a12628e0852, topicName=先心病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=25c8396, createdName=ssnine, createdTime=Sat Jan 12 10:32:00 CST 2019, time=2019-01-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1326096, encodeId=f0981326096ff, content=<a href='/topic/show?id=96c71804b7' target=_blank style='color:#2F92EE;'>#ACC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1804, encryptionId=96c71804b7, topicName=ACC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1e452500029, createdName=12498568m50暂无昵称, createdTime=Sat Jan 12 10:32:00 CST 2019, time=2019-01-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1561617, encodeId=d5da156161eeb, content=<a href='/topic/show?id=118142341b1' target=_blank style='color:#2F92EE;'>#增高#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=20, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=42341, encryptionId=118142341b1, topicName=增高)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=af9415191444, createdName=liuxiaona, createdTime=Sat Jan 12 10:32:00 CST 2019, time=2019-01-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1567626, encodeId=7868156e626f8, content=<a href='/topic/show?id=118142341b1' target=_blank style='color:#2F92EE;'>#增高#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=42341, encryptionId=118142341b1, topicName=增高)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=af9415191444, createdName=liuxiaona, createdTime=Sat Jan 12 10:32:00 CST 2019, time=2019-01-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=357772, encodeId=8a6435e77203, content=谢谢分享,学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6Nx0VGA4QMDzOP8oAgnV4h51EjSfehJ9QxyiaSmw8PB56BhY8KXFSxHCibXrzcy4abrzSibXQPxJ9kzrLcJyhhB8a/0, createdBy=1d3b1672603, createdName=明月清辉, createdTime=Thu Jan 10 21:01:53 CST 2019, time=2019-01-10, status=1, ipAttribution=)]
    2019-01-12 liuxiaona
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    2019-01-12 liuxiaona
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    2019-01-10 明月清辉

    谢谢分享,学习了

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