LANCET INFECT DIS:乳头蠕形螨病

2019-01-24 MedSci MedSci原创

一位40岁的妇女因其乳头有七个月的瘙痒史转诊至本诊所。一年前,她接受了舌鳞状细胞癌的完全切除。体格检查无明显异常,乳头区域无皮疹或退缩迹象。乳头皮肤镜检查和随后的活检显示存在大量蠕形螨(图A、B)。 毛囊蠕形螨属和短蠕形螨属两种蠕形螨属。毛囊中发现D卵泡,而短卵泡主要见于皮脂腺和睑板腺。虽然在乳头乳晕复合体中很常见,但蠕形螨通常无症状。1946年,加文在《柳叶刀》杂志上首次提出了蠕形螨与乳头

一位40岁的妇女因其乳头有七个月的瘙痒史转诊至本诊所。一年前,她接受了舌鳞状细胞癌的完全切除。体格检查无明显异常,乳头区域无皮疹或退缩迹象。乳头皮肤镜检查和随后的活检显示存在大量蠕形螨(图AB)。


毛囊蠕形螨属和短蠕形螨属两种蠕形螨属。毛囊中发现D卵泡,而短卵泡主要见于皮脂腺和睑板腺。虽然在乳头乳晕复合体中很常见,但蠕形螨通常无症状。1946年,加文在《柳叶刀》杂志上首次提出了蠕形螨与乳头疼痛的发病机制有关。其他原因乳头瘙痒还包括继发于接触或接触的湿疹特应性皮炎,慢性黏膜皮肤念珠菌病,达里尔氏病、淀粉样变、良性肿瘤等平滑肌瘤,恶性肿瘤(如Paget氏病)(由乳腺癌引起的),以及蠕形螨病。这些诊断通常会伴有皮疹提示其原因,而我们的病人没有任何皮肤症状。使用皮肤镜活检后,我们能够在没有其他病理变化证据的情况下确认蠕形螨。病人接受1%的局部治疗伊维菌素,每天两次,坚持一个月症状和彻底根,并且进一步由皮肤镜确认。乳头瘙痒提醒临床医生对蠕形螨病的怀疑,尽管该疾病是容易治疗和通常会被忽视的一种疾病。

原始出处:

Tal Zeeli, MD Prof Eli Sprecher, MD PhD, Demodicidosis of the nipple, CLINICAL PICTURE| VOLUME 19, ISSUE 1, P112, JANUARY 01, 2019

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    2019-02-23 howi
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    2019-03-05 wxl882001

    了解一下

    0

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    2019-02-09 wxl882001

    了解一下

    0

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